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ClinicalTrials.gov 24,857 recruiting now free trial finder

Find a clinical trial that's recruiting now

Search 24,857 actively recruiting US clinical trials by condition, drug, or state, each entry links straight to its NIH ClinicalTrials.gov record so you can check eligibility and contact the study team.

24,857
trials recruiting now
14%
of all US trials open to enrollment
52
states with recruiting sites

A trial is listed as recruiting when its sponsor has marked it open to new participants on the public registry. Type a condition or drug name (for example, "breast cancer" or "pembrolizumab") to narrow the list, and add a state to find studies with a site near you. Results are ordered with the most relevant recruiting studies first; each card shows the study phase and enrollment target, and opens the full record, including eligibility criteria and contact details, on ClinicalTrials.gov.

Showing the 40 largest recruiting trials by target enrollment in South Carolina. Use the search field to focus on a condition or drug.

Recruiting 2,000,000 participants

Helix Research Network

Helix

NCT06057181

Recruiting NA 21,350 participants

Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students

University of Virginia

NCT06047041

Recruiting 20,000 participants

Exactech Shoulder Post Market Clinical Follow-up Study

Exactech

NCT05603728

Recruiting Phase 3 7,600 participants

Preventing Alzheimer's With Cognitive Training

University of South Florida

NCT03848312

Recruiting 7,000 participants

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

Adela

NCT05366881

Recruiting Phase 4 6,000 participants

PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

Brigham and Women's Hospital

NCT05390892

Recruiting 5,000 participants

Collection of Tissue Samples for Cancer Research

National Cancer Institute (NCI)

NCT00900198

Recruiting 4,400 participants

Blue Light Cystoscopy With Cysview® Registry

Photocure

NCT02660645

Recruiting Phase 3 4,390 participants

A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)

Merck Sharp & Dohme

NCT07044297

Recruiting NA 4,000 participants

Pragmatic Trial to Enhance Quality Safety, and Patient Experience in COPD

Seattle Institute for Biomedical and Clinical Research

NCT05718102

Recruiting 3,000 participants

Rett Syndrome Registry

International Rett Syndrome Foundation

NCT05432349

Recruiting NA 2,894 participants

Healing, Equity, Advocacy and Respect for Mamas

Medical University of South Carolina

NCT06273436

Recruiting 2,500 participants

Total Shoulder Arthroplasty Multi-Center Registry

Arthrex

NCT03511586

Recruiting 2,000 participants

HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

University of Kansas Medical Center

NCT06425848

Recruiting 2,000 participants

Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

Arkansas Children's Hospital Research Institute

NCT05550298

Recruiting 2,000 participants

A Prospective Real World Evidence Study (PROWES) for Concordance Rate of Blood-based 3D Genome Conformation Mapping (Episwitch CiRT®) to Identify Likelihood of Response and Actual Response Rates to PD-(L)-1 Checkpoint Inhibitors Across Multiple Oncological Indications.

Oxford Biodynamics

NCT06635954

Recruiting 2,000 participants

Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

Michael J. Fox Foundation for Parkinson's Research

NCT06719583

Recruiting 2,000 participants

Pancreatic Cancer Detection Consortium

City of Hope Medical Center

NCT06388967

Recruiting NA 2,000 participants

VALOR: Vaginal Atrophy & Long-term Observation of Recovery

Stratpharma

NCT05953090

Recruiting 2,000 participants

Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy

Sequenom

NCT01429389

Recruiting Phase 3 1,900 participants

REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

Senseye

NCT07280065

Recruiting Phase 3 1,800 participants

Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

Kailera

NCT07284875

Recruiting Phase 3 1,700 participants

Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

Kailera

NCT07284901

Recruiting Phase 4 1,572 participants

DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

Ohio State University

NCT06445946

Recruiting 1,500 participants

Pulmonary Hemodynamics During Exercise - Research Network

Medical University of Graz

NCT03954574

Recruiting NA 1,316 participants

The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)

MeMed Diagnostics

NCT05762302

Recruiting NA 1,305 participants

The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia

University of Alabama at Birmingham

NCT04171323

Recruiting Phase 3 1,300 participants

A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 With Influenza Vaccine in Adults ≥ 50 Years of Age

Vaxcyte

NCT07365826

Recruiting Phase 3 1,200 participants

Efficacy and Safety of KAI-9531 Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes

Kailera

NCT07284979

Recruiting NA 1,200 participants

Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure

Analog Device

NCT05650541

Recruiting Phase 1 1,200 participants

Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)

Merck Sharp & Dohme

NCT02861573

Recruiting Phase 3 1,150 participants

AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

Novo Nordisk A/S

NCT07339423

Recruiting 1,051 participants

A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development

Ipsen

NCT06055725

Recruiting NA 1,040 participants

Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

University of Calgary

NCT05219110

Recruiting NA 1,024 participants

iAmHealthy Clinical Practice Guideline (CPG)

University of Kansas Medical Center

NCT06888011

Recruiting 1,000 participants

Testing Tumor Tissue and Blood to Help Select Personalized Treatments for Patients With Suspected Lung Cancers

Lung Cancer Mutation Consortium

NCT04712877

Recruiting 1,000 participants

Beat Childhood Cancer Specimen Banking and Data Registry

Giselle Sholler

NCT04715178

Recruiting 1,000 participants

Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure

Semmelweis University

NCT07016477

Recruiting 1,000 participants

Pivotal Study for the Cardiac Performance System (CPS)

Sensydia Corporation

NCT06870591

Recruiting 1,000 participants

A Post-Market Domestic (US) and International Data Collection to Assess the Truliant Knee System

Exactech

NCT05653102

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Recruiting status is reported by each study's sponsor and mirrored from the public registry. Always confirm current eligibility and status on ClinicalTrials.gov before contacting a study.

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