University of North Carolina, Chapel Hill

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of North Carolina, Chapel Hill sits in the top decile of US sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count).

1,109 total trials 108 currently recruiting 881 completed early-phase tilt top decile by trial count

University of North Carolina, Chapel Hill: 1,109 sponsored US clinical trials, 108 recruiting.

University of North Carolina, Chapel Hill sponsors 1,109 registered US clinical trials on ClinicalTrials.gov, 108 of them currently recruiting, and 881 completed. 69 of these trials are in Phase 3-4 (later-stage) and 203 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.

Top-decile sponsor footprint

University of North Carolina, Chapel Hill ranks in the top decile of sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 69/100

881 of 962 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,109 total, page 16 of 23

COMPLETED Phase 2

An Open Label Demonstration Project and Phase II Safety Study of Pre-Exposure Prophylaxis

NCT01772823

TERMINATED Phase 1

Platelet Rich Plasma vs. Corticosteroid Injection in the Treatment of Partial Rotator Cuff Tears

NCT01688362

TERMINATED Phase 1

Partner-Assisted Interpersonal Psychotherapy or Antidepressant Medication for Antenatal Depression

NCT01732055

COMPLETED NA

Internet-Based Osteoarthritis Pain Coping Skills Intervention

NCT01638871

COMPLETED

A Prospective Pharmacodynamic Study of Rivaroxaban

NCT01743898

COMPLETED NA

A Pilot Study of Plasma Renin Activity Guided vs Generic Combination Therapy for Hypertension

NCT01658657

COMPLETED NA

Dental Implant Study Comparing Two Types of Metals Used for Dental Implants

NCT01714024

COMPLETED NA

Vitamin D Absorption in HIV Infected Young Adults Being Treated With Tenofovir Containing cART

NCT01751646

COMPLETED NA

Plasma and Urine TMAO Formation and Changes to Oxidized LDL After Ingestion of Different Amounts of Egg

NCT01906554

COMPLETED NA

Does First Oral Intake After Emergence Predict the Incidence of Post-operative Vomiting in Children?

NCT01725399

COMPLETED NA

Auditory Brainstem Implantation in Young Children

NCT01904448

COMPLETED Phase 1

Intrauterine Lidocaine for Laminaria

NCT01541293

COMPLETED NA

Understanding and Discouraging Overuse of Potentially Harmful Screening Tests

NCT01694784

COMPLETED

Clinician Attitudes and Behaviors Regarding Use of Pre-Exposure Prophylaxis (PrEP) for Primary HIV Prevention

NCT01751659

COMPLETED NA

Cognitive De-Biasing and the Assessment of Pediatric Bipolar Disorder

NCT01799291

COMPLETED Phase 3

Understanding the Response to Fesoterodine Through Genetic Evaluation in the Elderly (URGE)

NCT01786967

COMPLETED NA

NCGENES: North Carolina Clinical Genomic Evaluation by NextGen Exome Sequencing

NCT01969370

COMPLETED Phase 4

Postpartum Etonogestrel Implant for Adolescents

NCT01666912

COMPLETED NA

Lung Cancer Surgery: Decisions Against Life Saving Care - The Intervention

NCT01687738

COMPLETED NA

FITShop: Promoting Physical Activity in Black Barbershops

NCT01699321

COMPLETED NA

ENLaCE Pilot Study

NCT01641211

COMPLETED NA

UCAN2: Uniting Couples in the Treatment of Anorexia Nervosa

NCT01740752

COMPLETED NA

Lose Now North Carolina Community Weight Loss Program

NCT01615471

COMPLETED NA

Examining The Role of CGM in T2DM

NCT01614262

COMPLETED NA

Study to Characterize the Durability of Hypertonic Saline to Enhance Mucociliary Clearance in Healthy Subjects

NCT01617369

COMPLETED

Persistent Pain Among Elderly Experiencing Motor Vehicle Collision

NCT02054962

COMPLETED NA

Study of Anesthesia Techniques to Reduce Nausea and Vomiting After Jaw Corrective Surgery

NCT01592708

COMPLETED NA

Goals of Care: A Nursing Home Trial of Decision Support for Advanced Dementia

NCT01565642

COMPLETED

Facilitating Completion of HPV Vaccination

NCT01600560

COMPLETED NA

Energy Expenditure and Substrate Utilization During Acute Under- and Over-feeding

NCT01740765

COMPLETED NA

Optimizing Outcomes in Women With Gestational Diabetes Mellitus and Their Infants

NCT01809431

COMPLETED

Reliability of Hertel Exophthalmometer Measurements

NCT01691183

COMPLETED NA

GooDMoMS: A Multimodel Pregnancy and Postpartum Intervention for Gestational Diabetics

NCT01600534

COMPLETED NA

Interactive Web-Based Tool for Pelvic Organ Prolapse: Impact on Patient Understanding and Provider Counseling

NCT01864408

COMPLETED Phase 1

Lipid Lowering Agents to Limit Lipid Oxidation and Activation of Clotting System in Nephrotic Syndrome

NCT01845428

COMPLETED

Acoustic Radiation Force Impulse (ARFI) Ultrasound for Noninvasive, Diagnostic Atherosclerosis Imaging

NCT01581385

COMPLETED NA

Testing a Secondary Prevention Intervention for HIV-Positive Black Young Men Who Have Sex With Men

NCT01751594

COMPLETED NA

Effects of Salpingectomy During Laparoscopic Hysterectomy on Ovarian Function

NCT01578759

COMPLETED NA

Mechanical Bowel Preparation Before Laparoscopic Hysterectomy and Laparoscopic Sacrocolpopexy: a Randomized Controlled Trial

NCT01576965

COMPLETED NA

Immediate Postplacental Insertion of IUDs at Time of Cesarean Delivery: A Randomized Clinical Trial

NCT01539759

COMPLETED NA

Evaluation of Behavioral Intervention for HIV Positive Prisoners in NC and TX

NCT01629316

COMPLETED Phase 4

Postpartum Levonorgestrel-releasing Intrauterine System and Breastfeeding

NCT01555931

COMPLETED

Mapping Multidimensional Illness Trajectories of Patients With End-stage Kidney Disease

NCT01530945

COMPLETED NA

Elders Preferences in Care Decisions

NCT01575990

COMPLETED NA

Dental Plaque Removal Study

NCT01559987

COMPLETED Phase 1

Pharmacokinetics of Tenofovir, Emtricitabine, Maraviroc, and Raltegravir in Cervical, Vaginal, and Rectal Tissues and Secretions

NCT01330199

COMPLETED Phase 2

Methotrexate in Induction and Maintenance of Steroid Free Remission in Ulcerative Colitis

NCT01393405

COMPLETED NA

Effect of Blueberries on Cognition and Body Composition in Elderly With Mild Cognitive Decline

NCT01515098

COMPLETED NA

Neural Markers and Rehabilitation of Executive Functioning in Veterans With Traumatic Brain Injury and Posttraumatic Stress Disorder

NCT01410721

COMPLETED

Double Push Acoustic Radiation Force (DP ARF) Ultrasound for Monitoring Degeneration in Duchenne Muscular Dystrophy

NCT01506518

← Previous Page 16 of 23 Next →

Phase Distribution

PhaseTrial count
Phase 1 111
Phase 2 92
Phase 3 13
Phase 4 56

What is open in the University of North Carolina, Chapel Hill pipeline

108 recruiting of 1,109 indexed (10% open); 881 completed (79%).

Phase mix: 69 late (III/IV) vs 203 early (I/II) (early-phase heavy).

Top condition: Obesity (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of North Carolina, Chapel Hill: open-pipeline peers nationwide

Peers matched on 1,109 registered trials and 10% open enrollment, not the therapeutic-area sidebar.

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share University of North Carolina, Chapel HillUniversity of FloridaWake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthChildren's Hospitals and Clinics of MinnesotaCytokineticsSanofiOhio University
University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,109 trials (± recruiting share)

Sponsors near 10% open enrollment (± trial volume)

What to do with this University of North Carolina, Chapel Hill page

1,109 registered trials is a research-attention snapshot, not an endorsement of University of North Carolina, Chapel Hill or any single study.

  • 108 of University of North Carolina, Chapel Hill's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition University of North Carolina, Chapel Hill studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of North Carolina, Chapel Hill pipeline card: 1,109 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.