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NCT01714024 · ClinicalTrials.gov registry record · NA
Dental Implant Study Comparing Two Types of Metals Used for Dental Implants
A NA study, sponsored by University of North Carolina, Chapel Hill.
- Completed
- Registry status
- NA
- Development phase
- 42
- Enrollment target
NCT01714024: Completed NA study, sponsored by University of North Carolina, Chapel Hill.
NCT01714024 is a NA study that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 42 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01714024, a NA study, has completed, sponsored by University of North Carolina, Chapel Hill.
- COMPLETED
- Registry status
- NA
- Development phase
- 42 participants
- Enrollment target
Study Summary
The purpose of this research study is to compare the healing differences of two metals (trabecular vs. standard titanium) that are used for dental implants. In addition; investigators will be examine these differences in the gene expression profiles in subjects with three conditions associated with delayed healing: diabetes and osteoporosis. The study will last at least 11 weeks consisting of 6 appointments. All visits will be carried out at the GO Health Center within the UNC School of Dentistry. Visits will last between 30 minutes to 3 hours depending on the particular visit. The visits will consist of: Obtaining consent, doing a health history, measuring vital signs, doing dental exams of the teeth and gums, collecting samples of saliva dental radiographs (X-rays), a teeth cleaning, having 4 temporary mini test cylinders placed in areas of the lower jaw where teeth are missing and implant surgery to place up to four permanent implants.
Primary Outcome
Samples were analyzed comparing the osteogenic potential associated with titanium and porous tantalum dental implants (cylinders) at 2 and 4 weeks using transcriptome analyses. The primary outcome data are displayed showing the Average Delta ∆ (Ct) for osteogenic genes relative to the housekeeping markers. The numerical value of the CT is inversely related to the amount of amplicon in the reaction (i.e., the lower the CT, the greater the amount of amplicon).
Interventions
- DEVICE Zimmer Trabecular Metal Test Cylinder
- DEVICE Zimmer Titanium Test Cylinder
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2012-10 |
| Est. Completion | 2015-05 |
| Phase | NA |
What the finished NCT01714024 record still lists
NCT01714024 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Zimmer Trabecular Metal Test Cylinder is the first listed.
NCT01714024 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01714024 about?
NCT01714024 is a clinical study titled "Dental Implant Study Comparing Two Types of Metals Used for Dental Implants". The purpose of this research study is to compare the healing differences of two metals (trabecular vs. standard titanium) that are used for dental implants. In addition; investigators will be examine these differences in the gene expression profiles in subjects with three conditions associated with ...
What is the current status of trial NCT01714024?
This trial is currently completed. It is a NA study. The enrollment target is 42 participants. The study started on 2012-10. Estimated completion is 2015-05.
What interventions are being tested in trial NCT01714024?
The interventions under investigation include: Zimmer Trabecular Metal Test Cylinder (DEVICE), Zimmer Titanium Test Cylinder (DEVICE).
Who is sponsoring clinical trial NCT01714024?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01714024's enrollment target sits among peer trials
42 1436th of 2000 higher than 555 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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