University of North Carolina, Chapel Hill

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of North Carolina, Chapel Hill sits in the top decile of US sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count).

1,109 total trials 108 currently recruiting 881 completed early-phase tilt top decile by trial count

University of North Carolina, Chapel Hill: 1,109 sponsored US clinical trials, 108 recruiting.

University of North Carolina, Chapel Hill sponsors 1,109 registered US clinical trials on ClinicalTrials.gov, 108 of them currently recruiting, and 881 completed. 69 of these trials are in Phase 3-4 (later-stage) and 203 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.

Top-decile sponsor footprint

University of North Carolina, Chapel Hill ranks in the top decile of sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 69/100

881 of 962 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,109 total, page 17 of 23

COMPLETED NA

Mindfulness: a Novel Approach for the Management of Diabetes-related Distress

NCT01805245

COMPLETED NA

Error Based Learning for Restoring Gait Symmetry Post-Stroke

NCT01598675

COMPLETED NA

Evaluation of a Dry Powder Aerosol Dispersion Mechanism by Radiolabeling Techniques

NCT01495442

COMPLETED Phase 1

Implementation of a Personalized Medicine (Pharmacogenomics) Service in a Community Pharmacy

NCT01495845

COMPLETED NA

Clinical Evaluation Of A New Two-Component Self-Etch Universal Adhesive

NCT01464996

COMPLETED

Evaluation of Allergenicity of Hypoallergenic Peanut Product in Peanut Allergic Subjects

NCT01489514

TERMINATED NA

Neurostimulation in Temporomandibular Disorders (TMD) Patients

NCT01502709

COMPLETED

HCV-TARGET- Hepatitis C Therapeutic Registry and Research Network

NCT01474811

COMPLETED NA

Connect to Protect (C2P): Building a Community-Based Infrastructure for HIV Prevention

NCT01752504

COMPLETED Phase 1

GSK1349572 Exposure in Blood, Seminal Fluid, and Rectal Fluid and Tissue in Healthy Male Subjects

NCT01459315

COMPLETED NA

Trial of Two Techniques to Assess Postoperative Voiding Function

NCT02150083

COMPLETED

Comparing Cardiac Output Measurements in Critically Ill Children Using USCOM and Transthoracic ECHO

NCT01460329

COMPLETED NA

Heart-Healthy Lenoir Lifestyle Study

NCT01433484

COMPLETED NA

Improving Care for Patients With High Blood Pressure

NCT01425515

COMPLETED NA

A School Health Center Intervention to Increase Adolescent Vaccination

NCT01595542

COMPLETED NA

Training Dual-Task Walking After Stroke

NCT01568957

COMPLETED

Correlates of Oral Human Papillomavirus Infection in Adolescents and Young Adults With Behaviorally Acquired HIV

NCT01492842

COMPLETED

Brain Connectivity in Neurodevelopmental Disorders in Response to Treatment

NCT01364818

TERMINATED Phase 1

Safety and Pharmacokinetics of Single and Multiple Dose Rifampin in Infants

NCT01441206

COMPLETED NA

Enhancement of Connect to Protect® (C2P)

NCT01492816

COMPLETED Phase 1

GSK1349572 Exposure in Blood, Cervicovaginal Fluid, and Cervical and Vaginal Tissue in Healthy Female Subjects

NCT01404806

COMPLETED

Families and Pediatric Cardiac Surgery Multidisciplinary Teams: How Well Do We Communicate

NCT01371864

COMPLETED NA

Online Study of Colorectal Cancer and Prostate Cancer Screening Decision Making

NCT01558583

COMPLETED Phase 1

Oxytocin Treatment of Social Cognitive and Functional Deficits in Schizophrenia

NCT01394471

COMPLETED

Is the Neosquamous Epithelium "Normal" Following Endoscopic Ablation of Dysplastic Barrett's Esophagus?

NCT01373125

COMPLETED Phase 1

Sublingual Immunotherapy for Peanut Allergy and Induction of Tolerance

NCT01373242

COMPLETED

Managerial Database II

NCT01322217

COMPLETED Phase 4

Short-Term Effects & Safety of an Accelerated Intravenous Iron Regimen in Patients With Heart Failure

NCT01925703

COMPLETED Phase 4

Pilot Study of Using Copeptin to Predict Response to Tolvaptan

NCT01346072

COMPLETED NA

Improving Money Management Skills for Veterans With Psychiatric Disabilities

NCT01352624

COMPLETED NA

Impact of Black Pepper on Energy Expenditure and Substrate Utilization

NCT01729143

COMPLETED NA

Examining Adolescent Assessment, Feedback, Incentive, and Exchange (AFIX) in North Carolina

NCT01544764

COMPLETED

Functional Modeling of the Pediatric Airway

NCT01690078

COMPLETED Early Phase 1

Facebook-based Physical Activity Intervention for Young Adult Cancer Survivors: the FITNET Randomized Pilot Study

NCT01349153

TERMINATED Phase 2

Early Methicillin-resistant Staphylococcus Aureus (MRSA) Therapy in Cystic Fibrosis (CF)

NCT01349192

COMPLETED NA

Cardiovascular Effects in Psoriasis Patients Treated With Adalimumab.

NCT01320293

COMPLETED

Racial Disparity in Barrett's Esophagus

NCT01374074

COMPLETED Phase 2

Tadalafil for Sarcoidosis Associated Pulmonary Hypertension

NCT01324999

COMPLETED Phase 2

A Study of Oxytocin in Children and Adolescents With Autistic Disorder

NCT01308749

COMPLETED Phase 1

Curcumin Pharmacokinetics

NCT01330810

COMPLETED NA

Study of A Cell-Phone System to Improve Health of Youth With Diabetes

NCT02280564

COMPLETED Phase 1

The Effect of Vorinostat on HIV RNA Expression in the Resting CD4+ T Cells of HIV+ Pts on Stable ART

NCT01319383

COMPLETED NA

Heart to Health: A Combined Lifestyle and Medication Intervention to Reduce Cardiovascular Disease (CVD) Risk

NCT01245686

COMPLETED NA

A Study Comparing the Interproximal Plaque and Gingivitis Effects of Three Interdental Cleaning Modalities

NCT01307358

COMPLETED NA

The WEIGH Study: Weighing to Improve and Gain Health

NCT01369004

TERMINATED NA

Home Hypnotherapy for Refractory Functional Chest Pain: A Pilot Study

NCT01284179

COMPLETED NA

Family PALS (PArtners in Lifestyle Support)

NCT01324011

COMPLETED NA

Decision Support Interventions (DESI) for Prostate Cancer Screening - Study 1

NCT01241656

COMPLETED Phase 1

Bioavailability Study Comparing Tolvaptan Administered Via Nasogastric Tube to Tolvaptan Tablets Swallowed Intact

NCT01261481

COMPLETED NA

Effects of Sulforaphane (SFN) on Immune Response to Live Attenuated Influenza Virus in Smokers and Nonsmokers

NCT01269723

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Phase Distribution

PhaseTrial count
Phase 1 111
Phase 2 92
Phase 3 13
Phase 4 56

What is open in the University of North Carolina, Chapel Hill pipeline

108 recruiting of 1,109 indexed (10% open); 881 completed (79%).

Phase mix: 69 late (III/IV) vs 203 early (I/II) (early-phase heavy).

Top condition: Obesity (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of North Carolina, Chapel Hill: open-pipeline peers nationwide

Peers matched on 1,109 registered trials and 10% open enrollment, not the therapeutic-area sidebar.

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share University of North Carolina, Chapel HillUniversity of FloridaWake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthChildren's Hospitals and Clinics of MinnesotaCytokineticsSanofiOhio University
University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,109 trials (± recruiting share)

Sponsors near 10% open enrollment (± trial volume)

What to do with this University of North Carolina, Chapel Hill page

1,109 registered trials is a research-attention snapshot, not an endorsement of University of North Carolina, Chapel Hill or any single study.

  • 108 of University of North Carolina, Chapel Hill's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition University of North Carolina, Chapel Hill studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of North Carolina, Chapel Hill pipeline card: 1,109 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.