University of North Carolina, Chapel Hill

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of North Carolina, Chapel Hill sits in the top decile of US sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count).

1,109 total trials 108 currently recruiting 881 completed early-phase tilt top decile by trial count

University of North Carolina, Chapel Hill: 1,109 sponsored US clinical trials, 108 recruiting.

University of North Carolina, Chapel Hill sponsors 1,109 registered US clinical trials on ClinicalTrials.gov, 108 of them currently recruiting, and 881 completed. 69 of these trials are in Phase 3-4 (later-stage) and 203 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.

Top-decile sponsor footprint

University of North Carolina, Chapel Hill ranks in the top decile of sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 69/100

881 of 962 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,109 total, page 15 of 23

COMPLETED NA

Mothers and Others: Family-based Obesity Prevention for Infants and Toddlers

NCT01938118

COMPLETED NA

Effect of Sulforaphane-rich Broccoli Sprout Homogenate on Ozone Induced Inflammation Through Modulation of NRF2

NCT01625130

COMPLETED NA

Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability

NCT01615484

COMPLETED Phase 1

Study of Wellness Behaviors as a Function of Oxytocin vs Placebo

NCT01929161

COMPLETED NA

A Transgenerational e-Intervention for Gestational Diabetics and Their Offspring

NCT01931280

COMPLETED Phase 2

Effect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell Disease

NCT01732718

COMPLETED NA

Wellness Intervention for Menstrual Mood Disorders

NCT01995916

COMPLETED NA

Can a Rapid 2 Day Followup After Discharge From the ED Reduce Readmissions and Death for Patients 75 Years and Older?

NCT01769495

COMPLETED NA

Diffusion Weighted MR Imaging of the Breasts in Women at High Risk of Breast Cancer: A Pilot Study

NCT01938157

COMPLETED NA

Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and Parturition

NCT01762943

COMPLETED NA

Use of a Brief Phone Call After ED Discharge

NCT01893931

COMPLETED NA

Physical Activity to Reduce Joint Pain During Aromatase Inhibitor Therapy

NCT01900418

COMPLETED

Study of Exposure to Stress, Postpartum Mood, Adverse Life Events, and Hormonal Function Among Latinas (SEPAH Latina)

NCT01912833

COMPLETED NA

Padres Efectivos (Parent Activation): Skills Latina Mothers Use to Get Healthcare for Their Children

NCT02329431

COMPLETED

Determining the Barriers and Motivations to Clinical Trial Participation

NCT01937091

TERMINATED Early Phase 1

Nutritional Supplementation Effects on Rehabilitation Outcomes in Rotator Cuff Pathology

NCT01798693

COMPLETED NA

Microfinance and Health Intervention Trial for Youth in Dar es Salaam, Tanzania

NCT01865383

COMPLETED

Observational Assessment of Baseline Asthma Control in African-American Children

NCT01891630

COMPLETED NA

Pilot Study on Ambulatory Intraocular Pressure and Blood Pressure Monitoring in Glaucoma

NCT01912599

COMPLETED NA

Shoe Lifts for Leg Length Inequality in Adults With Knee or Hip Symptoms

NCT01894100

COMPLETED

Fluid Intake Application to Reduce Kidney Stone Risks

NCT01928108

COMPLETED NA

Rethinking Eating and FITness for Men

NCT01843595

COMPLETED

Anorexia Nervosa Genetics Initiative

NCT01916538

COMPLETED Phase 4

The Effect of Anticholinergics on Cognitive Function in the Elderly

NCT01922115

COMPLETED

Factors Affecting PrEP Adherence

NCT02411630

COMPLETED NA

Brief Intervention to Create Smoke-Free Homes Policies in Low-Income Households: North Carolina Effectiveness Trial

NCT01868672

COMPLETED

chemQbiosciences:Manual Liquid Based Cytology

NCT01837303

COMPLETED NA

Prophylactic Modified McCall Culdoplasty During Total Laparoscopic Hysterectomy

NCT01840176

COMPLETED Phase 4

Control of Tourniquet Pain With an Axillary Ring of Subcutaneous Local Anesthetic

NCT01829399

COMPLETED Phase 1

Sulforaphane Supplementation in Atopic Asthmatics

NCT01845493

COMPLETED NA

Keys to Healthy Family Child Care Homes

NCT01814215

COMPLETED Phase 2

Mechanisms of Desensitization During Peanut Oral Immunotherapy

NCT01814241

COMPLETED NA

Accountability for Cancer Care Through Undoing Racism and Equity

NCT01954641

COMPLETED NA

Technology to Enhance Treatment for Early Conduct Problems in Low Income Families

NCT02191956

COMPLETED Phase 2

An Open Label Demonstration Project and Phase II Safety Study of Pre-Exposure Prophylaxis Use Among 15 to 17 Year Old Young Men Who Have Sex With Men (YMSM)

NCT01769456

COMPLETED NA

Feasibility of Using a Structured Daily Diary

NCT01953653

COMPLETED Phase 1

Pharmacokinetics of Sildenafil in Premature Infants

NCT01670136

COMPLETED Phase 4

Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis

NCT01825408

COMPLETED NA

Sustained Effects of Hypertonic Saline on Mucociliary Clearance in Subjects With Chronic Bronchitis

NCT01792271

COMPLETED

Prevalence of Dysplasia of the Gastric Cardia

NCT01787864

COMPLETED NA

Effect of Beta-Alanine on Heart Rate Response

NCT01745016

COMPLETED NA

Project ACCEPT: Engaging Newly Diagnosed HIV+ Youth in Care

NCT01751620

COMPLETED

The Pathogenesis of Hepatitis C Virus Vertical Transmission

NCT01921400

COMPLETED

Comparing Validity of Non-Invasive Hemoglobin Monitoring to Laboratory Results in Critically Ill Children

NCT01750463

TERMINATED NA

Educational-Medical-Behavioral Treatment of Fecal Incontinence

NCT01717456

COMPLETED Phase 2

Study of Lurasidone in Treating Antipsychotic Naive or Quasi-Naive Children and Adolescents

NCT01731119

COMPLETED

Renal, Endocrine, and Bone Changes in Response to FTC/TDF in Uninfected Young Men Who Have Sex With Men (YMSM).

NCT01769469

COMPLETED NA

Nutritional Prevention of Exertional Muscle Dysfunction

NCT01722448

COMPLETED NA

Effect of ASEA on Energy Expenditure and Fat Oxidation in Humans

NCT01884727

COMPLETED Phase 1

Altered Drug Disposition and Biomarkers for Diagnosis of Chronic Inflammatory Liver Disease

NCT01766960

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Phase Distribution

PhaseTrial count
Phase 1 111
Phase 2 92
Phase 3 13
Phase 4 56

What is open in the University of North Carolina, Chapel Hill pipeline

108 recruiting of 1,109 indexed (10% open); 881 completed (79%).

Phase mix: 69 late (III/IV) vs 203 early (I/II) (early-phase heavy).

Top condition: Obesity (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of North Carolina, Chapel Hill: open-pipeline peers nationwide

Peers matched on 1,109 registered trials and 10% open enrollment, not the therapeutic-area sidebar.

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share University of North Carolina, Chapel HillUniversity of FloridaWake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthChildren's Hospitals and Clinics of MinnesotaCytokineticsSanofiOhio University
University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,109 trials (± recruiting share)

Sponsors near 10% open enrollment (± trial volume)

What to do with this University of North Carolina, Chapel Hill page

1,109 registered trials is a research-attention snapshot, not an endorsement of University of North Carolina, Chapel Hill or any single study.

  • 108 of University of North Carolina, Chapel Hill's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition University of North Carolina, Chapel Hill studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of North Carolina, Chapel Hill pipeline card: 1,109 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.