University of Michigan

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of Michigan sits in the top decile of US sponsors by registered trial count (#19 of 15,742 sponsors by registered trial count).

1,327 total trials 179 currently recruiting 971 completed early-phase tilt top decile by trial count

University of Michigan: 1,327 sponsored US clinical trials, 179 recruiting.

University of Michigan sponsors 1,327 registered US clinical trials on ClinicalTrials.gov, 179 of them currently recruiting, and 971 completed. 94 of these trials are in Phase 3-4 (later-stage) and 159 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Depression, with 15 trials.

Top-decile sponsor footprint

University of Michigan ranks in the top decile of sponsors by registered trial count (#19 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 64/100

971 of 1,083 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,327 total, page 10 of 27

COMPLETED Early Phase 1

Effect of Chewing a Calcium Supplement Before Fluoride Rinse on Salivary Fluoride

NCT04620252

COMPLETED NA

Improving Depression Via E-Health Access (IDEA) Study

NCT04689568

COMPLETED NA

How do the Neck Muscles Influence Head Acceleration During Sport-associated Impact Events in High School Athletes?

NCT03883165

COMPLETED NA

The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy.

NCT04675775

COMPLETED Phase 4

Metformin as an Adjunctive Therapy to Catheter Ablation in Atrial Fibrillation

NCT04625946

COMPLETED NA

Previously Implanted Pudendal Nerve Stimulation

NCT04473469

COMPLETED NA

Non-Pharmaceutical Intervention for Cirrhotic Cramps Reduction: The NICCles Trial

NCT04650295

COMPLETED NA

Targeting Normoxia in Neonates With Cyanotic Congenital Heart Disease in the Intra-operative and Immediate Post-operative Period

NCT04452188

COMPLETED NA

Addressing Violence and HIV Care Among Transgender Women

NCT04813484

COMPLETED

Utilizing CT Based Imaging Parameters of Body Composition to Understand Heterogeneity of Response to Biologic Therapies in Severe Asthma Cohorts

NCT06922760

COMPLETED NA

Prevention Interventions for Opioid Misuse

NCT04550715

COMPLETED

Psychological and Clinical Factors That Predict Intent to Deprescribe Medications Among Older Adults

NCT04676282

COMPLETED NA

Pilot Testing a New Pregnancy Decision Making Tool for Women With Physical Disabilities

NCT04651114

COMPLETED NA

STIM+: PET Biomarker Education & Disclosure

NCT04818255

COMPLETED NA

Improving Outcomes for Care Partners of Persons With Traumatic Brain Injury

NCT04570930

COMPLETED

Incidence and Predictors of Acute and Chronic Complications in Patients With Diabetes and Severe COVID-19

NCT05200819

COMPLETED NA

MOMSonLINE2 ; A Pilot Study Testing Recruitment and Retention of Women of Color to an Online Support Group for Bereaved Mothers

NCT04600076

COMPLETED NA

Effect of Peripheral Neuromodulation on Vaginal Blood Flow

NCT04384172

COMPLETED NA

Mobile Technology and Data Analytics to Identify Real-time Predictors of Caregiver Well-Being

NCT04556591

COMPLETED NA

Feasibility and Preliminary Effects of the Resilience-based, Energy Management to Enhance Wellbeing in Systemic Sclerosis (RENEW) Intervention

NCT04588714

COMPLETED NA

Virtual AppLication-supported ENvironment To INcrease Exercise During Cardiac Rehabilitation Study

NCT04587882

COMPLETED Phase 1

WeCareAdvisor: A Web-Based Tool to Improve Quality of Life for Military Veterans With Dementia and Their Caregivers

NCT04587583

COMPLETED NA

My MS Toolkit + Coaching: A Guided Web-based Symptom Self-Management Program for People With MS

NCT04552561

COMPLETED NA

Brief Intervention Combined With Health Coaching Via Social Media for Cannabis Use

NCT04316741

COMPLETED NA

Facilitating Use of the National Suicide Prevention Lifeline in Alcohol Patients (Reach Out)

NCT04488055

TERMINATED NA

Light at Night Study

NCT04251234

COMPLETED

C-myc Biomarker Study for Diabetic Foot Ulcers

NCT04591691

TERMINATED NA

The Optimization of Medications in Chronic Heart Failure Using a Website

NCT04580004

COMPLETED NA

Michigan Alcohol Improvement Network- Alcohol Reduction and Treatment Trial

NCT04473482

COMPLETED NA

A Systems-Level Intervention for Rural Adults With Depression

NCT04502186

COMPLETED NA

Pudendal Nerve Mapping Towards Improved Neuromodulation for Urinary Retention

NCT04236596

COMPLETED NA

Recombinant Human Platelet-derived Growth Factor in Combination With Collagen Matrix

NCT04462237

COMPLETED

Studying Students at Risk for COVID-19

NCT04766788

COMPLETED NA

No Power Bionic Lower Extremity Prosthesis

NCT04070105

COMPLETED NA

Psychosocial Pain Management to Improve Opioid Use Disorder Treatment Outcomes

NCT04433975

COMPLETED NA

Effects of Low FODMAP Diet on Colonic Epithelial Physiology in Diarrhea-predominant Irritable Bowel Syndrome

NCT04542018

COMPLETED NA

Screening and Intervention for Glaucoma and Eye Health Through Telemedicine

NCT04274764

COMPLETED

Automated Quantitative Ulcer Analysis Study

NCT04420962

COMPLETED NA

HealthyLifetime: Health Coaching for Older Adults

NCT05070923

COMPLETED

Mechanistic Study of Ocrevus

NCT04459988

COMPLETED

TEWL Biomarker Study for Diabetic Foot Ulcer Recurrence

NCT04558775

COMPLETED

Ultrasound Crestal Bone Topography of Edentulous Ridges

NCT04487379

COMPLETED NA

Comparing the Effects of Exercise on the Structure and Function of Fat Tissue

NCT05328570

COMPLETED Phase 2

Dipyridamole to Prevent Coronavirus Exacerbation of Respiratory Status (DICER) in COVID-19

NCT04391179

COMPLETED NA

Project IntERact Study

NCT03940716

COMPLETED NA

Positive Psychology for Chronic Pain Self-management

NCT04321239

COMPLETED NA

Providing Mental Health Precision Treatment

NCT04342494

COMPLETED NA

Effect of Academic Detailing to Reduce Opioid Prescribing in Dentistry

NCT04425668

COMPLETED

Monitoring Health Care Workers at Risk for COVID-19 Using Wearable Sensors and Smartphone Technology

NCT04756869

COMPLETED NA

Intern Health Study: 2020 Cohort Micro-Randomized Trial

NCT05106439

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Phase Distribution

PhaseTrial count
Phase 1 79
Phase 2 80
Phase 3 25
Phase 4 69

What is open in the University of Michigan pipeline

179 recruiting of 1,327 indexed (13% open); 971 completed (73%).

Phase mix: 94 late (III/IV) vs 159 early (I/II) (early-phase heavy).

Top condition: Depression (15 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of Michigan: open-pipeline peers nationwide

Peers matched on 1,327 registered trials and 13% open enrollment, not the therapeutic-area sidebar.

University of Michigan sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 0%5%10%15%20%25% Total trials Recruiting share University of MichiganEli Lilly and CompanyGlaxoSmithKlineAstraZenecaUniversity of Colorado, DenverWayne State UniversityCase Comprehensive Cancer CenterAlbany Medical CollegeTaiho Oncology
University of Michigan sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of Michigan sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,327 trials (± recruiting share)

Sponsors near 13% open enrollment (± trial volume)

What to do with this University of Michigan page

1,327 registered trials is a research-attention snapshot, not an endorsement of University of Michigan or any single study.

  • 179 of University of Michigan's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Depression is the condition University of Michigan studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Depression trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of Michigan pipeline card: 1,327 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.