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NCT06922760 · ClinicalTrials.gov registry record
Utilizing CT Based Imaging Parameters of Body Composition to Understand Heterogeneity of Response to Biologic Therapies in Severe Asthma Cohorts
A clinical trial, sponsored by University of Michigan.
- Completed
- Registry status
- 233
- Enrollment target
NCT06922760: Completed study, sponsored by University of Michigan.
NCT06922760 is a clinical trial that has completed, run by University of Michigan. The registered enrollment target is 233 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06922760 has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- 233 participants
- Enrollment target
Study Summary
This study will utilize University of Michigan EMR data to form a retrospective cohort of severe asthma patients on biologic therapies for asthma with computed tomography (CT) imaging and known outcomes on therapy. These images will then be analyzed using morphomics, a combination of high-throughput image analysis and deep learning techniques, to derive imaging biomarkers that will be able to predict therapeutic response to biologics. These biomarkers will then be tested in a second cohort from the National Jewish Health to assess for validity.
Primary Outcome
Muscle size was measured as the skeletal muscle cross-sectional area in centimeters squared (cm2) measured at the level of the T10 vertebra to determine the cutoff value in chest wall muscle size that optimally classified patients that had and did not have any reduction in pre-treatment baseline exacerbation frequency (binary).
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 233 participants |
| Start Date | 2021-01-15 |
| Est. Completion | 2024-07-31 |
What the finished NCT06922760 record still lists
NCT06922760 is an observational study that tracks outcomes without assigning an intervention. The registered 233 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT06922760 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06922760 about?
NCT06922760 is a clinical study titled "Utilizing CT Based Imaging Parameters of Body Composition to Understand Heterogeneity of Response to Biologic Therapies in Severe Asthma Cohorts". This study will utilize University of Michigan EMR data to form a retrospective cohort of severe asthma patients on biologic therapies for asthma with computed tomography (CT) imaging and known outcomes on therapy. These images will then be analyzed using morphomics, a combination of high-throughput...
What is the current status of trial NCT06922760?
This trial is currently completed. The enrollment target is 233 participants. The study started on 2021-01-15. Estimated completion is 2024-07-31.
Who is sponsoring clinical trial NCT06922760?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
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