UNC Lineberger Comprehensive Cancer Center

366 total trials 79 currently recruiting 209 completed

UNC Lineberger Comprehensive Cancer Center sponsors 366 registered US clinical trials on ClinicalTrials.gov, 79 of them currently recruiting, and 209 completed. 2 of these trials are in Phase 3-4 (later-stage) and 157 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 29 trials.

Trial Pipeline

366 total, page 2 of 8

RECRUITING NA

The Care Tracker Study: Using Patient-Reported Data to Address Racial Disparity in Cancer Treatment

NCT06096623

RECRUITING Phase 1

ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer

NCT05542407

RECRUITING

Brain Slice Explants to Predict Drug Response in Brain Tumors

NCT05978557

RECRUITING Early Phase 1

Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer

NCT05620342

RECRUITING

Disease Outcomes and Toxicities in Patients With Gastrointestinal and Sarcomatous Malignancies

NCT05743426

RECRUITING Early Phase 1

Comparison of CE-DBT and MRI in Patients With Known Breast Lesions

NCT05754749

RECRUITING

Young Adult Infusion Space Experience Satisfaction Survey

NCT05720546

RECRUITING NA

Evaluation of Child Care Staff Weight Management Program

NCT05656807

RECRUITING NA

Adaptation of a Values Assessment Tool

NCT07068477

RECRUITING Phase 2

Study of Trilaciclib and Lurbinectidin

NCT05578326

RECRUITING Phase 1

Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc

NCT05366179

RECRUITING

Evaluation of the Acceptability, Appropriateness, and Feasibility/Usability of a Metastatic Breast-cancer Specific Prognostic Calculator Among Clinicians

NCT05440929

RECRUITING Phase 2

Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy

NCT05472792

RECRUITING Phase 2

Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

NCT05145400

RECRUITING

UNC Childhood, Adolescent, and Young Adult Cancer Cohort

NCT05096923

RECRUITING

Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC

NCT04564989

RECRUITING Phase 1

Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.

NCT04223765

RECRUITING

Circulating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell Carcinoma

NCT04099290

RECRUITING

MRI Biomarkers for Radiation-Induced Neurocognitive Decline Following SRS of Newly Diagnosed Brain Mets

NCT04073966

RECRUITING Phase 2

CD30 CAR for Relapsed/Refractory CD30+ T Cell Lymphoma

NCT04083495

RECRUITING Phase 2

Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer

NCT03977233

RECRUITING Phase 1

Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma

NCT03721068

RECRUITING NA

Harnessing Analysis RNA Expression and Molecular Subtype to Optimize Novel TherapY MBCA

NCT03769415

RECRUITING

Registry for Adults With Plasma Cell Disorders (PCD's)

NCT03717844

RECRUITING Phase 1

Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors

NCT03454035

RECRUITING

UNC Pleural Fluid Registry

NCT05620329

RECRUITING

Registry of Older Patients With Cancer

NCT01137825

RECRUITING

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

NCT01137643

RECRUITING

Correlation of Molecular Markers With Response to Therapy and Breast Cancer Behavior

NCT01000883

ACTIVE NOT RECRUITING NA

Physical Activity Centers Empowerment

NCT06411756

ACTIVE NOT RECRUITING Phase 2

Isa-Pom-Dex in Elderly/Frail Subjects With RRMM

NCT05911321

ACTIVE NOT RECRUITING NA

Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers

NCT05823740

ACTIVE NOT RECRUITING NA

Impact of Financial Incentives

NCT05744960

ACTIVE NOT RECRUITING NA

Impact of Standing Orders Optimization

NCT05742386

ACTIVE NOT RECRUITING Phase 2

Polatuzumab Vedotin With R-GDP in Relapsed/Refractory Diffuse Large B-cell Lymphoma

NCT05498220

ACTIVE NOT RECRUITING

Long-Term Follow-Up in Women With Early Breast Cancer Three Years of More Post Primary Treatment

NCT05926024

ACTIVE NOT RECRUITING Phase 2

Pembrolizumab Plus Olaparib in LA-HNSCC

NCT05366166

ACTIVE NOT RECRUITING

Patient Related Outcomes for Gynecologic Radiation Oncology

NCT04753086

ACTIVE NOT RECRUITING NA

PRO-VISION: Patient Reported Outcomes-Based Monitoring of VEGF-Inhibitor Side Effects in ONcology

NCT05592665

ACTIVE NOT RECRUITING

Immuno-Oncology Database and Bioregistry

NCT04656873

ACTIVE NOT RECRUITING Phase 1

Phase I Study of Autologous CAR T-Cells Targeting the B7-H3 Antigen in Recurrent Epithelial Ovarian

NCT04670068

ACTIVE NOT RECRUITING Phase 2

A Pilot Study of Acalabrutinib in Relapsed/Refractory Primary and Secondary CNS Lymphomas

NCT04548648

ACTIVE NOT RECRUITING Phase 2

Window of Opportunity Study of Pembrolizumab Alone and in Combinations in Bladder Cancer

NCT03978624

ACTIVE NOT RECRUITING Phase 2

Durvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN

NCT03529422

ACTIVE NOT RECRUITING Early Phase 1

Study of PD-1 Inhibitors After CD30.CAR T Cell Therapy in Relapsed/Refractory Hodgkin Lymphoma

NCT04134325

ACTIVE NOT RECRUITING Phase 1

Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma

NCT03696784

ACTIVE NOT RECRUITING Phase 1

Study of ATLCAR.CD138 Cells for Relapsed/Refractory Multiple Myeloma

NCT03672318

ACTIVE NOT RECRUITING Phase 1

Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL

NCT03602157

ACTIVE NOT RECRUITING Phase 2

BV-CHEP Chemotherapy for Adult T-cell Leukemia or Lymphoma

NCT03264131

ACTIVE NOT RECRUITING Phase 2

Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Carcinoma

NCT03174275

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Phase Distribution

PhaseTrial count
Phase 1 71
Phase 2 86
Phase 3 1
Phase 4 1

What the Pipeline for UNC Lineberger Comprehensive Cancer Center Shows

According to the ClinicalTrials.gov registry, UNC Lineberger Comprehensive Cancer Center is linked to 366 US clinical trials across every stage of research activity. Of those, 79 studies are currently recruiting, about 22% of the sponsor's indexed portfolio, and 209 are already marked complete, representing roughly 57% of the total.

The phase mix for UNC Lineberger Comprehensive Cancer Center reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 157 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for UNC Lineberger Comprehensive Cancer Center is Breast Cancer with 29 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.