UNC Lineberger Comprehensive Cancer Center
UNC Lineberger Comprehensive Cancer Center sponsors 366 registered US clinical trials on ClinicalTrials.gov, 79 of them currently recruiting, and 209 completed. 2 of these trials are in Phase 3-4 (later-stage) and 157 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 29 trials.
Trial Pipeline
366 total, page 2 of 8
The Care Tracker Study: Using Patient-Reported Data to Address Racial Disparity in Cancer Treatment
NCT06096623
ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer
NCT05542407
Brain Slice Explants to Predict Drug Response in Brain Tumors
NCT05978557
Autologous CAR T-Cells Targeting the GD2 Antigen for Lung Cancer
NCT05620342
Disease Outcomes and Toxicities in Patients With Gastrointestinal and Sarcomatous Malignancies
NCT05743426
Comparison of CE-DBT and MRI in Patients With Known Breast Lesions
NCT05754749
Young Adult Infusion Space Experience Satisfaction Survey
NCT05720546
Evaluation of Child Care Staff Weight Management Program
NCT05656807
Adaptation of a Values Assessment Tool
NCT07068477
Study of Trilaciclib and Lurbinectidin
NCT05578326
Autologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc
NCT05366179
Evaluation of the Acceptability, Appropriateness, and Feasibility/Usability of a Metastatic Breast-cancer Specific Prognostic Calculator Among Clinicians
NCT05440929
Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy
NCT05472792
Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma
NCT05145400
UNC Childhood, Adolescent, and Young Adult Cancer Cohort
NCT05096923
Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC
NCT04564989
Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
NCT04223765
Circulating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell Carcinoma
NCT04099290
MRI Biomarkers for Radiation-Induced Neurocognitive Decline Following SRS of Newly Diagnosed Brain Mets
NCT04073966
CD30 CAR for Relapsed/Refractory CD30+ T Cell Lymphoma
NCT04083495
Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer
NCT03977233
Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma
NCT03721068
Harnessing Analysis RNA Expression and Molecular Subtype to Optimize Novel TherapY MBCA
NCT03769415
Registry for Adults With Plasma Cell Disorders (PCD's)
NCT03717844
Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors
NCT03454035
UNC Pleural Fluid Registry
NCT05620329
Registry of Older Patients With Cancer
NCT01137825
Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
NCT01137643
Correlation of Molecular Markers With Response to Therapy and Breast Cancer Behavior
NCT01000883
Physical Activity Centers Empowerment
NCT06411756
Isa-Pom-Dex in Elderly/Frail Subjects With RRMM
NCT05911321
Measuring Changes in Body Composition and Physical Function in Patients With Childhood Cancers
NCT05823740
Impact of Financial Incentives
NCT05744960
Impact of Standing Orders Optimization
NCT05742386
Polatuzumab Vedotin With R-GDP in Relapsed/Refractory Diffuse Large B-cell Lymphoma
NCT05498220
Long-Term Follow-Up in Women With Early Breast Cancer Three Years of More Post Primary Treatment
NCT05926024
Pembrolizumab Plus Olaparib in LA-HNSCC
NCT05366166
Patient Related Outcomes for Gynecologic Radiation Oncology
NCT04753086
PRO-VISION: Patient Reported Outcomes-Based Monitoring of VEGF-Inhibitor Side Effects in ONcology
NCT05592665
Immuno-Oncology Database and Bioregistry
NCT04656873
Phase I Study of Autologous CAR T-Cells Targeting the B7-H3 Antigen in Recurrent Epithelial Ovarian
NCT04670068
A Pilot Study of Acalabrutinib in Relapsed/Refractory Primary and Secondary CNS Lymphomas
NCT04548648
Window of Opportunity Study of Pembrolizumab Alone and in Combinations in Bladder Cancer
NCT03978624
Durvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN
NCT03529422
Study of PD-1 Inhibitors After CD30.CAR T Cell Therapy in Relapsed/Refractory Hodgkin Lymphoma
NCT04134325
Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma
NCT03696784
Study of ATLCAR.CD138 Cells for Relapsed/Refractory Multiple Myeloma
NCT03672318
Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL
NCT03602157
BV-CHEP Chemotherapy for Adult T-cell Leukemia or Lymphoma
NCT03264131
Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Carcinoma
NCT03174275
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 71 |
| Phase 2 | 86 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Therapeutic Areas
What the Pipeline for UNC Lineberger Comprehensive Cancer Center Shows
According to the ClinicalTrials.gov registry, UNC Lineberger Comprehensive Cancer Center is linked to 366 US clinical trials across every stage of research activity. Of those, 79 studies are currently recruiting, about 22% of the sponsor's indexed portfolio, and 209 are already marked complete, representing roughly 57% of the total.
The phase mix for UNC Lineberger Comprehensive Cancer Center reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 157 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for UNC Lineberger Comprehensive Cancer Center is Breast Cancer with 29 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.