UNC Lineberger Comprehensive Cancer Center

366 total trials 79 currently recruiting 209 completed

UNC Lineberger Comprehensive Cancer Center sponsors 366 registered US clinical trials on ClinicalTrials.gov, 79 of them currently recruiting, and 209 completed. 2 of these trials are in Phase 3-4 (later-stage) and 157 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 29 trials.

Trial Pipeline

366 total, page 3 of 8

ACTIVE NOT RECRUITING Phase 1

Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL

NCT02690545

ACTIVE NOT RECRUITING Phase 1

Administration of T Lymphocytes for Prevention of Relapse of Lymphomas

NCT02663297

ACTIVE NOT RECRUITING Phase 1

Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL

NCT03016377

NOT YET RECRUITING NA

Improving Affordability in Cancer Care Through Economic Screening and Support (I-ACCESS)

NCT07664436

NOT YET RECRUITING NA

Optimization of Dietary Adherence in a Mobile Weight Loss Intervention

NCT07582536

NOT YET RECRUITING NA

Evaluation of Impact of AI Assistance on Workload Associated w Preparation of Rare Tumor Case Repts

NCT06026098

NOT YET RECRUITING

Incorporating Biometric Data for Patients Receiving Concurrent Chemotherapy & RT

NCT05937659

NOT YET RECRUITING Phase 2

Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial Cancer

NCT07078838

NOT YET RECRUITING NA

The PharmFIT Study

NCT06656936

NOT YET RECRUITING NA

Overcoming Barriers to Uptake of Cascade Screening

NCT07304063

NOT YET RECRUITING Phase 2

Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease

NCT07685938

NOT YET RECRUITING Phase 2

Study on Treatment Outcome Patterns for Patients With CLL After Discontinuation of BTK Inhibitors

NCT07526597

NOT YET RECRUITING NA

Virtual Testis Cancer Lay Support and Survivorship Aim 2

NCT06702592

NOT YET RECRUITING NA

SURGIMEDIA: Utilization of Multimedia for Enhanced Surgical Consent

NCT07494994

NOT YET RECRUITING Phase 2

Revumenib, Azacitidine, and VENetoclax in Newly Diagnosed KMT2A-Rearranged AML

NCT07605949

NOT YET RECRUITING NA

Strength Training Exercise in Pediatric Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (STEP-ALL)

NCT07634653

NOT YET RECRUITING Phase 2

Effects of Infusion Timing on Treatment Response in Solid Tumors

NCT07630168

NOT YET RECRUITING

C-3002: Enhancing Cervical Cancer Screening Access and Follow-up Care at 'CASCADE' Clinical Sites in the United States

NCT07520188

NOT YET RECRUITING Phase 2

Olomorasib + Pembrolizumab KRAS G12C Mutant, PD-L1 TPS 1-49% Locally Advanced or Metastatic NSCLC

NCT07639242

NOT YET RECRUITING Phase 2

H&N NEO-COMBAT XL: Neoadjuvant XL-092 (Zanzalintinib) and Pembrolizumab (Keytruda) in Surgically Resectable, HPV Negative Oral Cavity Squamous Cell Carcinoma (OCSCC)

NCT07484139

COMPLETED NA

Piloting a Reinforcement Learning Tool for Individually Tailoring Just-in-time Adaptive Interventions

NCT05751993

COMPLETED NA

Social Media Posts About Cancer: Five Timepoints

NCT07588607

COMPLETED

VisR for Noninvasively Interrogating Stromal Collagen Organization as a Breast Cancer Biomarker: Evaluation of Compression in Control Subjects

NCT06547034

COMPLETED NA

Effective Ads for Quitting Smoking

NCT06485479

COMPLETED NA

Little Cigar and Cigarillo Warnings to Reduce Tobacco-Related Cancers and Disease - Eye Tracking

NCT06546618

COMPLETED NA

Little Cigar and Cigarillo Warnings for Youth

NCT06413797

TERMINATED Phase 1

Abequolixron (RGX-104) and Durvalumab in Lung Cancer

NCT05911308

COMPLETED NA

Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors

NCT06171945

COMPLETED NA

Impact of E-Cigarette Prevention Messages on Adolescents

NCT05985538

COMPLETED NA

Physical Activity and Healthy Eating Among Young Adult Cancer Survivors

NCT05887401

COMPLETED

Physical Therapy in Pre-cystectomy Patients

NCT05978570

COMPLETED NA

Little Cigar and Cigarillo Warnings Among US Adults Who Use LCCs

NCT05849051

COMPLETED NA

enCompass Carolina: A Social Support and Coaching Program for Cancer Caregivers

NCT05828927

TERMINATED NA

Intervention to Address Psychosocial Needs Among Socially Disadvantaged Older Adults With Cancer

NCT05828654

COMPLETED

Assessing Functional Status Needs Via PRO Measures for Pts With Metastatic Breast Cancer

NCT05755347

COMPLETED

Risk Stratification for Patients With Hospital-diagnosed Advanced Lung Cancer

NCT05722847

COMPLETED NA

Engaging Clinical Champions to Improve HPV Vaccination

NCT05736718

COMPLETED NA

Impact of E-cigarette Device Warnings

NCT05714982

COMPLETED

ctDNA in Subjects With Muscle-invasive Bladder Cancer Treated With Trimodality Therapy

NCT05630131

COMPLETED

Impact of Physical and Occupational Therapy in New BMT Patients

NCT05978583

COMPLETED Phase 2

CD30 CAR for CD30+ NSGCT

NCT05634785

COMPLETED

Physical Function During ARSI Treatment

NCT05612880

COMPLETED

Metastatic Breast Cancer-Specific Prognostic Tool

NCT05574478

COMPLETED NA

The Families Addressing Cancer Together Intervention for Parents With Cancer

NCT05377749

TERMINATED Phase 2

3-D Super Resolution Ultrasound Microvascular Imaging

NCT04136912

COMPLETED NA

Mobile Health App to Promote Participation of Black Women in Breast Cancer Clinical Trials

NCT06361056

COMPLETED

Pre-Implementation Study of Improving Thoracic Surgical Care Using Electronic Patient-Reported Outcomes (ePROS)

NCT05311670

COMPLETED

Understanding What Matters Most to Patients: Establishing the Validity of a Best-Worst Scaling Survey

NCT05061095

COMPLETED

Connecting Audio and Radio Sensing Systems to Improve Care at Home

NCT05344950

TERMINATED

Patient and Care Partner Experiences Living With Multiple Myeloma (PaCE-MM)

NCT05276622

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Phase Distribution

PhaseTrial count
Phase 1 71
Phase 2 86
Phase 3 1
Phase 4 1

What the Pipeline for UNC Lineberger Comprehensive Cancer Center Shows

According to the ClinicalTrials.gov registry, UNC Lineberger Comprehensive Cancer Center is linked to 366 US clinical trials across every stage of research activity. Of those, 79 studies are currently recruiting, about 22% of the sponsor's indexed portfolio, and 209 are already marked complete, representing roughly 57% of the total.

The phase mix for UNC Lineberger Comprehensive Cancer Center reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 157 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for UNC Lineberger Comprehensive Cancer Center is Breast Cancer with 29 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.