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ClinicalTrials.gov 6 recruiting now early-phase tilt small index

Immune System Diseases: early-phase trial registry

6 of 19 indexed Immune System Diseases trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #902 of 28,707 conditions by registered trial count.

19 US clinical trials · 6 currently recruiting · #902 of 28,707 conditions by registered trial count

Immune System Diseases: 19 US clinical trials tracked, 6 recruiting.

Immune System Diseases is the subject of 19 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most active sponsor is UNC Lineberger Comprehensive Cancer Center, running 7 of these trials.

Enrollment posture brief

Registry condition immune-system-diseases

OPEN 6 | RECR 32% | LATE 1 | EARLY 13 | RANK #902 | SPON 7

Nearest open-share peer: Back Pain (32% recruiting · 38 trials)

Amyotrophic Lateral Sclerosi52.6%Anesthesia, Local42.1%Alcohol Consumption36.8%Immune System Diseases (this)32%Attention Deficit Hyperactiv26.3%
Open-enrollment share among volume-matched conditions near Immune System Diseases

Immune System Diseases lists 6 open slots (32% of 19 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Immune System Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Immune System Diseases is recruiting below its size-band peers.

    6 of 19 indexed trials (31.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Immune System Diseases research.

    UNC Lineberger Comprehensive Cancer Center accounts for 7 of 19 trials (36.8%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Most Immune System Diseases trials plan to enrol fewer than 100 people.

    Median target enrolment is 43 among the 19 trials that report a genuine target (sentinel values excluded). 15 of those (78.9%) plan for fewer than 100 participants.

  4. Immune System Diseases research is mostly interventional.

    15 interventional and 4 observational studies make up this index (78.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 26Phase 41

Open and recent trials

19 total, page 1 of 1

RECRUITING 800 participants

Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00001406

RECRUITING 600 participants

Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00006150

RECRUITING Phase 2 354 participants

Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

National Cancer Institute (NCI)

NCT02579967

RECRUITING Phase 2 330 participants

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

National Cancer Institute (NCI)

NCT03922724

RECRUITING Phase 2 66 participants

Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity

National Cancer Institute (NCI)

NCT04339777

RECRUITING Phase 2 39 participants

A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition

Memorial Sloan Kettering Cancer Center

NCT05787574

ACTIVE NOT RECRUITING Phase 2 90 participants

A Safety and Efficacy Study of PVX108 in Children and Adolescents With Peanut Allergy

Aravax Pty

NCT05621317

ACTIVE NOT RECRUITING Phase 2 71 participants

Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation

National Cancer Institute (NCI)

NCT03663933

ACTIVE NOT RECRUITING Phase 1 43 participants

Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL

UNC Lineberger Comprehensive Cancer Center

NCT03602157

ACTIVE NOT RECRUITING Phase 1 38 participants

Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL

UNC Lineberger Comprehensive Cancer Center

NCT02690545

ACTIVE NOT RECRUITING 32 participants

Immuno-Oncology Database and Bioregistry

UNC Lineberger Comprehensive Cancer Center

NCT04656873

ACTIVE NOT RECRUITING Phase 1 25 participants

Study of ATLCAR.CD138 Cells for Relapsed/Refractory Multiple Myeloma

UNC Lineberger Comprehensive Cancer Center

NCT03672318

ACTIVE NOT RECRUITING Phase 1 19 participants

Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma

UNC Lineberger Comprehensive Cancer Center

NCT03696784

ACTIVE NOT RECRUITING Phase 1 18 participants

Administration of T Lymphocytes for Prevention of Relapse of Lymphomas

UNC Lineberger Comprehensive Cancer Center

NCT02663297

ACTIVE NOT RECRUITING Phase 1 17 participants

Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL

UNC Lineberger Comprehensive Cancer Center

NCT03016377

COMPLETED NA 95 participants

Asthma Data Innovation Demonstration Project

David Van Sickle

NCT02162576

COMPLETED 48 participants

Humoral and T-Cell Responses to COVID-19 Vaccination in Multiple Sclerosis Patients Treated With Ocrelizumab Treated With Ocrelizumab or Natalizumab

Dragonfly Research

NCT04837651

COMPLETED Phase 4 33 participants

Mesalamine to Reduce T Cell Activation in HIV Infection

University of California, San Francisco

NCT01090102

COMPLETED Phase 1 30 participants

A Study of Safety and Drug Levels of HIB210 in Healthy Volunteers

HI-Bio, A Biogen Company

NCT05928585

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 6
Phase 4 1

Named interventions

Most-linked intervention names on Immune System Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Fludarabine Drug
4 trials
Bendamustine Drug
2 trials
GVHD Prophylaxis Drug
2 trials
Placebo Drug
2 trials
Cyclophosphamide Drug
2 trials
Propeller Health intervention Device
1 trials
T-Detect COVID T-cell blood test Device
1 trials
Elecsys semi-quantitative Anti-SARS-CoV-2 antibody test Device
1 trials

US sites by state

Facility locations filed on Immune System Diseases trials. A trial with sites in several states counts in each.

North Carolina 8 trials
Maryland 7 trials
Minnesota 3 trials
California 3 trials
Massachusetts 2 trials
Georgia 2 trials
Wisconsin 1 trials
Texas 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Immune System Diseases page

19 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Immune System Diseases condition card totals 19 registered trials; most-linked intervention Fludarabine; top US site state North Carolina. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.