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NCT04099290 · ClinicalTrials.gov registry record
Circulating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell Carcinoma
A clinical trial of Carcinoma, Squamous Cell and Head and Neck Neoplasm, sponsored by UNC Lineberger Comprehensive Cancer Center.
- Recruiting
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT04099290: Recruiting study of Carcinoma, Squamous Cell and Head and Neck Neoplasm, sponsored by UNC Lineberger Comprehensive Cancer Center.
NCT04099290 is a study of Carcinoma, Squamous Cell and Head and Neck Neoplasm that is actively recruiting participants, run by UNC Lineberger Comprehensive Cancer Center. The registered enrollment target is 50 participants, below the 257-participant average among 14 other Carcinoma, Squamous Cell trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04099290, a study of Carcinoma, Squamous Cell and Head and Neck Neoplasm, is actively recruiting participants, sponsored by UNC Lineberger Comprehensive Cancer Center.
- RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Circulating tumor DNA (ctDNA) is a blood-based test that measures dying or dead cancer cells that are already circulating in the blood. In this study, the investigators will enroll patients who are planning to receive surgery to remove their head and neck cancer. The investigators are interested to learn how ctDNA levels change with surgery and over the course of time. The investigators also want to determine if there are certain features of the tumor or the patient themselves that might cause ctDNA to be higher than other patients. Also, the investigators want to explore if the detection of ctDNA following surgery is related to cancer recurrence.
Conditions Studied
Interventions
- OTHER Blood and tumor samples
Study Locations (1)
North Carolina
- University of North Carolina at Chapel Hill - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2020-01-14 |
| Est. Completion | 2027-02-01 |
What NCT04099290 shows while recruiting
NCT04099290 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 257-participant average among 14 other Carcinoma, Squamous Cell trials with a reported enrollment target (81% lower).
The record links to 2 conditions, with Carcinoma, Squamous Cell appearing as the primary indexed condition, and to 1 intervention - of which Blood and tumor samples is the first listed.
NCT04099290 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT04099290 about?
NCT04099290 is a clinical study titled "Circulating Tumor DNA (ctDNA) in Locally Advanced Head and Neck Squamous Cell Carcinoma". Circulating tumor DNA (ctDNA) is a blood-based test that measures dying or dead cancer cells that are already circulating in the blood. In this study, the investigators will enroll patients who are planning to receive surgery to remove their head and neck cancer. The investigators are interested to ...
What is the current status of trial NCT04099290?
This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2020-01-14. Estimated completion is 2027-02-01.
What conditions does trial NCT04099290 study?
This clinical trial studies the following conditions: Carcinoma, Squamous Cell, Head and Neck Neoplasm.
What interventions are being tested in trial NCT04099290?
The interventions under investigation include: Blood and tumor samples (OTHER).
Who is sponsoring clinical trial NCT04099290?
This trial is sponsored by UNC Lineberger Comprehensive Cancer Center, which has 366 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04099290 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04099290's enrollment target sits among peer trials
50 9th of 14 higher than 6 of 14 other Carcinoma, Squamous Cell trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Carcinoma, Squamous Cell trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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