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NCT06896162 · ClinicalTrials.gov registry record · NA
PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival
A NA study of Breast Cancer and Lung Cancer, sponsored by UNC Lineberger Comprehensive Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 500
- Enrollment target
- 1
- Study location
NCT06896162: Recruiting NA study of Breast Cancer and Lung Cancer, sponsored by UNC Lineberger Comprehensive Cancer Center.
NCT06896162 is a NA study of Breast Cancer and Lung Cancer that is actively recruiting participants, run by UNC Lineberger Comprehensive Cancer Center. The registered enrollment target is 500 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06896162, a NA study of Breast Cancer and Lung Cancer, is actively recruiting participants, sponsored by UNC Lineberger Comprehensive Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 500 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a hybrid decentralized, single-arm, interventional study designed to evaluate the impact of precision medicine navigation and reflexive expert review of next-generation sequencing (NGS) for patients with stage IV solid tumor malignancies (breast, lung, colorectal, and bladder cancers). The purpose of this study is to investigate whether intervention from a centralized precision oncology navigator and expert review of NGS results by the precision oncology pharmacist will increase ordering of Level 1/2 genome informed therapy (GIT) compared to an estimated historical rate of 15%. Secondary endpoints will assess the impact of a centralized precision oncology navigator and expert review of NGS results on enrollment in biomarker-directed clinical trials and overall survival at 2 years after return of NGS results. The study will take approximately 12 months for enrolment and 2 years of follow-up after the date of NGS results.
Primary Outcome
The rate of genome informed therapy (GIT) orders for Level 1/2 GIT will be compared against an estimated baseline historical GIT order.
Conditions Studied
Interventions
- OTHER Expert Review
- OTHER Blood or tissue samples collection.
- OTHER The Precision Oncology Navigation
Study Locations (1)
North Carolina
- Lineberger Comprehensive Cancer Center, University of North Carolina - Chapel Hill
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 500 participants |
| Start Date | 2025-06-27 |
| Est. Completion | 2028-06 |
| Phase | NA |
What NCT06896162 shows while recruiting
NCT06896162 is an interventional study that assigns participants to a tested intervention. The registered 500 participants enrollment target is mid-sized for trials with a published cap, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (82% lower).
The record links to 6 conditions, with Breast Cancer appearing as the primary indexed condition, and to 3 interventions - of which Expert Review is the first listed.
NCT06896162 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT06896162 about?
NCT06896162 is a clinical study titled "PROGRESS: Precision Oncology Using Genomic Reflexive Evaluations for Study Selection and Survival". This is a hybrid decentralized, single-arm, interventional study designed to evaluate the impact of precision medicine navigation and reflexive expert review of next-generation sequencing (NGS) for patients with stage IV solid tumor malignancies (breast, lung, colorectal, and bladder cancers). The ...
What is the current status of trial NCT06896162?
This trial is currently recruiting. It is a NA study. The enrollment target is 500 participants. The study started on 2025-06-27. Estimated completion is 2028-06.
What conditions does trial NCT06896162 study?
This clinical trial studies the following conditions: Breast Cancer, Lung Cancer, Colorectal Cancer, Bladder Cancer, Metastatic Cancer.
What interventions are being tested in trial NCT06896162?
The interventions under investigation include: Expert Review (OTHER), Blood or tissue samples collection. (OTHER), The Precision Oncology Navigation (OTHER).
Who is sponsoring clinical trial NCT06896162?
This trial is sponsored by UNC Lineberger Comprehensive Cancer Center, which has 366 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06896162 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06896162's enrollment target sits among peer trials
500 193rd of 1224 higher than 1,022 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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