Tufts Medical Center

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Tufts Medical Center sits in the top decile of US sponsors by registered trial count (#171 of 15,742 sponsors by registered trial count).

169 total trials 18 currently recruiting 111 completed early-phase tilt top decile by trial count

Tufts Medical Center: 169 sponsored US clinical trials, 18 recruiting.

Tufts Medical Center sponsors 169 registered US clinical trials on ClinicalTrials.gov, 18 of them currently recruiting, and 111 completed. 27 of these trials are in Phase 3-4 (later-stage) and 44 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Heart Failure, with 5 trials.

Top-decile sponsor footprint

Tufts Medical Center ranks in the top decile of sponsors by registered trial count (#171 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 39/100

111 of 139 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (79.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

169 total, page 2 of 4

COMPLETED

Relationship Between Strain and Stroke Volume in Cardiac Surgery

NCT04694378

COMPLETED Phase 2

Niclosamide for Mild to Moderate COVID-19

NCT04399356

TERMINATED Phase 4

Intracanalicular Dexamethasone Insert for the Treatment of Inflammation and Discomfort in Dry Eye Disease (DEcIDED)

NCT04527887

COMPLETED NA

Mind-body Therapy (Remotely Delivered) for Knee Osteoarthritis

NCT04678999

COMPLETED

Screening to Improve Survival in AL Amyloidosis

NCT04615572

COMPLETED Phase 2

Apremilast 30 mg Twice Daily (BID) Combined With Dupilumab

NCT04306965

COMPLETED Phase 2

A Phase 2 Trial of Infliximab in Coronavirus Disease 2019 (COVID-19).

NCT04425538

TERMINATED Phase 2

Inhaled Nitric Oxide for Preventing Progression in COVID-19

NCT04388683

TERMINATED NA

Effects of High Flow Nasal Cannula on Sputum Clearance in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

NCT04217746

COMPLETED

Cervical Stiffness Measurement in Cervical Insufficiency

NCT04158401

TERMINATED Phase 4

Predicting the Success of Dry Eye Disease Interventions Using Clinical Tests

NCT04125134

COMPLETED NA

Defining the 'Sniffing Position" in Infants and Toddlers - A Pilot Study

NCT04410289

TERMINATED Phase 2

H+ Mobilization With Dialysate Bicarbonate Variation

NCT04020757

COMPLETED NA

Prepared Meals to Prime and Perpetuate Reduced Dietary Sodium Intake in Hemodialysis

NCT03990311

COMPLETED Phase 3

Increased Ketorolac Administration After Cesarean Section and Its Effect on Opioid Use: a Randomized Control Trial

NCT03678675

COMPLETED

Body Composition Ultrasound for Patients With Heart Failure

NCT03948776

COMPLETED NA

Genomic Medicine for Ill Neonates and Infants (The GEMINI Study)

NCT03890679

TERMINATED Phase 1

Treatment of Macular Edema After Cataract Surgery with Subconjunctival Aflibercept

NCT03396861

COMPLETED NA

Audio-Visual Relaxation Technology for Pediatric Amplified Musculoskeletal Pain Syndrome

NCT03762213

TERMINATED NA

Intranasal Neurostimulation in Ameliorating Symptoms of Neuropathic Corneal Pain

NCT03674892

COMPLETED NA

Durapore vs. Hy-Tape to Secure The Endotracheal Tube

NCT03633877

COMPLETED NA

Tegaderm vs. EyeGard for Eye Protection

NCT03549429

COMPLETED NA

Music vs. No Music During Cesarean Delivery on Patient Satisfaction

NCT03412019

COMPLETED Phase 1

Fractionated Docetaxel and Radium 223 in Metastatic Castration-Resistant Prostate Cancer

NCT03737370

COMPLETED Phase 4

Intrathecal Chloroprocaine vs. Bupivacaine for Cervical Cerclage

NCT03305575

TERMINATED Phase 2

Renal AL Amyloid Involvement and NEOD001

NCT03168906

COMPLETED

Incidence and Nature of Respiratory Impairment in Consecutive Patients Undergoing Bronchoscopy Under Conscious Sedation: A Pilot Study

NCT03886454

COMPLETED Phase 2

Dialysate Sodium Lowering Trial

NCT03144817

TERMINATED Early Phase 1

Oral Tofacitinib in Adult Subjects With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE)

NCT03159936

COMPLETED NA

Lifestyle Intervention in Preparation for Pregnancy (LIPP)

NCT03146156

TERMINATED Phase 4

Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids

NCT02977286

COMPLETED NA

Supporting Mothers of Preterm Infants

NCT03013660

TERMINATED Phase 1

Trial of Venetoclax (ABT-199) and Dexamethasone for Relapsed or Refractory Systemic AL Amyloidosis

NCT03000660

COMPLETED Early Phase 1

Exploratory Trial Evaluating Cosentyx (Secukinumab) for Patients With Moderate-to-Severe Hidradenitis Suppurativa

NCT03099980

COMPLETED Phase 3

Preoperative Acetaminophen and Carbohydrate Loading

NCT03131713

COMPLETED Phase 2

Safety of PZ-128 in Subjects Undergoing Non-Emergent Percutaneous Coronary Intervention

NCT02561000

TERMINATED NA

Do Single Use Negative Pressure Dressings Reduce Wound Complications in Obese Women After Cesarean Delivery

NCT02799667

COMPLETED

A Diagnostic Screening Trial Seeking AL Amyloidosis Very Early

NCT02741999

COMPLETED Phase 2

Topical Ruxolitinib for the Treatment of Vitiligo

NCT02809976

COMPLETED

Minimal Residual Disease as a Possible Predictive Factor for Relapse in Patients With AL Amyloidosis

NCT02555969

COMPLETED NA

Effectiveness of the Aeroneb in Acute Severe Asthma

NCT03029156

COMPLETED NA

Pilot Study of Physiological Effect of High-Flow Nasal Cannula on Respiratory Pattern and Work of Breathing

NCT02514798

COMPLETED NA

Tai Chi Intervention and Brain Imaging Study Among Fibromyalgia Patients and Healthy Controls

NCT02407665

COMPLETED

Evaluation of Non-Invasive Respiratory Volume Monitor

NCT03039881

COMPLETED NA

Clinical Hemodynamic Study of Balloon Counterpulsation in Advanced Heart Failure

NCT03001674

COMPLETED NA

A Study of a Technology-enabled Disease Management Program to Reduce Hospitalizations for Heart Failure

NCT02084992

COMPLETED Phase 2

Diet as a Potential Treatment for Autosomal Dominant Polycystic Kidney Disease

NCT02225860

TERMINATED

Treatment of Dyspnea in Do-not-intubate Patients

NCT02114944

COMPLETED Phase 4

The Utility of IVCM to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With DED

NCT02120079

COMPLETED

Ocular Surface Immune Response in Dry Eye Disease

NCT02042820

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What is open in the Tufts Medical Center pipeline

18 recruiting of 169 indexed (11% open); 111 completed (66%).

Phase mix: 27 late (III/IV) vs 44 early (I/II) (early-phase heavy).

Top condition: Heart Failure (5 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Tufts Medical Center: open-pipeline peers nationwide

Peers matched on 169 registered trials and 11% open enrollment, not the therapeutic-area sidebar.

Tufts Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150200 0%5%10%15%20% Total trials Recruiting share Tufts Medical CenterAstellas Pharma Global DevelopmentBausch Health AmericasSeattle Children's HospitalSumitomo Pharma AmericaHartford HospitalUConn HealthCAMC Health SystemBastyr University
Tufts Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Tufts Medical Center sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 169 trials (± recruiting share)

Sponsors near 11% open enrollment (± trial volume)

What to do with this Tufts Medical Center page

169 registered trials is a research-attention snapshot, not an endorsement of Tufts Medical Center or any single study.

  • 18 of Tufts Medical Center's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Heart Failure is the condition Tufts Medical Center studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Heart Failure trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Tufts Medical Center pipeline card: 169 registered trials from official public datasets.Report a data error.