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NCT04678999 · ClinicalTrials.gov registry record · NA
Mind-body Therapy (Remotely Delivered) for Knee Osteoarthritis
A NA study, sponsored by Tufts Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 50
- Enrollment target
NCT04678999: Completed NA study, sponsored by Tufts Medical Center.
NCT04678999 is a NA study that has completed, run by Tufts Medical Center. The registered enrollment target is 50 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04678999, a NA study, has completed, sponsored by Tufts Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
Study Summary
This proposal aims to provide crucial knowledge about the neurobiological mechanisms underlying Tai Chi mind-body therapy for knee osteoarthritis (OA). The central mechanism of knee OA pain will be investigated using brain imaging technology to evaluate how brain function and structure change in response to mind-body exercise over time. Sixty eligible individuals who meet the American College of Rheumatology criteria for knee OA will be randomized into Tai Chi or wellness education interventions for 12 weeks. The investigators will compare changes in resting state functional connectivity of the cognitive control network, and functional magnetic resonance imaging responses to pressure pain and brain morphometry, as well as their association with clinical outcomes. The findings will lead to the establishment of a new treatment paradigm in OA and have broad application to the management of chronic musculoskeletal pain.
Primary Outcome
Change in resting state functional connectivity between baseline to 12 weeks as measured by fMRI.
Interventions
- BEHAVIORAL Mind-body exercise and education
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2020-09-01 |
| Est. Completion | 2022-11-30 |
| Phase | NA |
What the finished NCT04678999 record still lists
NCT04678999 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 1 intervention - of which Mind-body exercise and education is the first listed.
NCT04678999 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04678999 about?
NCT04678999 is a clinical study titled "Mind-body Therapy (Remotely Delivered) for Knee Osteoarthritis". This proposal aims to provide crucial knowledge about the neurobiological mechanisms underlying Tai Chi mind-body therapy for knee osteoarthritis (OA). The central mechanism of knee OA pain will be investigated using brain imaging technology to evaluate how brain function and structure change in res...
What is the current status of trial NCT04678999?
This trial is currently completed. It is a NA study. The enrollment target is 50 participants. The study started on 2020-09-01. Estimated completion is 2022-11-30.
What interventions are being tested in trial NCT04678999?
The interventions under investigation include: Mind-body exercise and education (BEHAVIORAL).
Who is sponsoring clinical trial NCT04678999?
This trial is sponsored by Tufts Medical Center, which has 169 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04678999's enrollment target sits among peer trials
50 1279th of 2000 higher than 622 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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