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2026 data Public-data reference. official source

Cardiogenic Shock

Open-data reference.

17 US clinical trials · 14 currently recruiting

Active & Recent Trials

RECRUITING 5,000 participants

Cardiogenic Shock Working Group Registry

Tufts Medical Center

NCT04682483

RECRUITING 3,000 participants

Inova Cardiogenic Shock Registry (INOVA SHOCK)

Inova Health Care Services

NCT03378739

RECRUITING 500 participants

Multi-center Collaborative to Enhance Quality and Outcomes in the Management of Cardiogenic Shock

STAVROS G DRAKOS

NCT05185492

RECRUITING NA 400 participants

Pulmonary Artery Catheter in Cardiogenic Shock Trial

Tufts Medical Center

NCT05485376

RECRUITING 200 participants

Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock

University of Minnesota

NCT05426083

RECRUITING NA 144 participants

Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock

Ottawa Heart Institute Research Corporation

NCT05298124

RECRUITING Phase 2 104 participants

Physiology of Unloading VA ECMO Trial

University of Utah

NCT06336655

RECRUITING 60 participants

Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure

Tufts Medical Center

NCT06253104

RECRUITING Phase 2 50 participants

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

Stanford University

NCT06080074

RECRUITING NA 40 participants

Hemodynamic Monitoring to Prevent Adverse Events foLlowing cardiOgenic Shock Trial

Inova Health Care Services

NCT04419480

RECRUITING 30 participants

Pre-Emptive LAVA-ECMO for Complex High-Risk TAVR

Atlantic Health System

NCT07309029

RECRUITING NA 25 participants

Augmented Pacing for Shock in the Cardiac Intensive Care Unit

Vanderbilt University Medical Center

NCT06713668

RECRUITING 20 participants

Intra-aortic Balloon Counterpulsation (IABC) Compliance

Thomas Jefferson University

NCT07402018

RECRUITING Early Phase 1 5 participants

Cardiac Power Output in Cardiogenic Shock Patients

University of Chicago

NCT05700617

ACTIVE NOT RECRUITING Phase 1 20 participants

A Safety and Efficacy Trial of Istaroxime for Cardiogenic Shock Stage C

Windtree Therapeutics

NCT05975021

COMPLETED 406 participants

National Cardiogenic Shock Initiative

Henry Ford Health System

NCT03677180

COMPLETED 150 participants

PPCM Observational Study (Peripartum Cardiomyopathy)

Medical College of Wisconsin

NCT04234659

Phase Distribution

PhaseTrial count
Early Phase 1 2
Phase 2 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Cardiogenic Shock Trial Landscape

ClinicalTrials.gov lists 17 US studies indexed under Cardiogenic Shock, and 14 of those are currently open to recruitment — roughly 82% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Cardiogenic Shock shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Cardiogenic Shock is led by Tufts Medical Center with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 17 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Cardiogenic Shock?

PlainTrial tracks 17 US clinical trials for Cardiogenic Shock, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cardiogenic Shock?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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