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Cardiogenic Shock clinical trials
14 of 17 indexed Cardiogenic Shock trials are currently recruiting.
17 US clinical trials · 14 currently recruiting
Cardiogenic Shock is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Tufts Medical Center, running 3 of these trials.
The research picture
Cardiogenic Shock has 17 registered US clinical trials, 14 of them open to new participants right now, about 82% of the total.
- 14
- recruiting participants now
- 82%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Tufts Medical Center
Active & Recent Trials
17 total, page 1 of 1
Cardiogenic Shock Working Group Registry
Tufts Medical Center
NCT04682483
Inova Cardiogenic Shock Registry (INOVA SHOCK)
Inova Health Care Services
NCT03378739
Multi-center Collaborative to Enhance Quality and Outcomes in the Management of Cardiogenic Shock
Stavros G Drakos
NCT05185492
Pulmonary Artery Catheter in Cardiogenic Shock Trial
Tufts Medical Center
NCT05485376
Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock
University of Minnesota
NCT05426083
Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock
Ottawa Heart Institute Research Corporation
NCT05298124
Physiology of Unloading VA ECMO Trial
University of Utah
NCT06336655
Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure
Tufts Medical Center
NCT06253104
Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System
Stanford University
NCT06080074
Hemodynamic Monitoring to Prevent Adverse Events foLlowing cardiOgenic Shock Trial
Inova Health Care Services
NCT04419480
Pre-Emptive LAVA-ECMO for Complex High-Risk TAVR
Atlantic Health System
NCT07309029
Augmented Pacing for Shock in the Cardiac Intensive Care Unit
Vanderbilt University Medical Center
NCT06713668
Intra-aortic Balloon Counterpulsation (IABC) Compliance
Thomas Jefferson University
NCT07402018
Cardiac Power Output in Cardiogenic Shock Patients
University of Chicago
NCT05700617
A Safety and Efficacy Trial of Istaroxime for Cardiogenic Shock Stage C
Windtree Therapeutics
NCT05975021
National Cardiogenic Shock Initiative
Henry Ford Health System
NCT03677180
PPCM Observational Study (Peripartum Cardiomyopathy)
Medical College of Wisconsin
NCT04234659
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cardiogenic Shock Trial Landscape
17 indexed Cardiogenic Shock studies · 14 recruiting (82%).
Phase mix: 0 late (III/IV) vs 4 early (I/II).
Top sponsor: Tufts Medical Center (3 trials), 9 others listed. 17 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cardiogenic Shock?
PlainTrial tracks 17 US clinical trials for Cardiogenic Shock, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cardiogenic Shock?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.