Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 14 recruiting now early-phase tilt small index

Cardiogenic Shock: early-phase trial registry

14 of 17 indexed Cardiogenic Shock trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,004 of 28,707 conditions by registered trial count.

17 US clinical trials · 14 currently recruiting · #1,004 of 28,707 conditions by registered trial count

Cardiogenic Shock: 17 US clinical trials tracked, 14 recruiting.

Cardiogenic Shock is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Tufts Medical Center, running 3 of these trials.

Enrollment posture brief

Registry condition cardiogenic-shock

OPEN 14 | RECR 82% | LATE 0 | EARLY 4 | RANK #1004 | SPON 3

Nearest open-share peer: Stargardt Disease (82% recruiting · 17 trials)

Cardiogenic Shock (this)82%Acute Myeloid Leukemia, in R70.6%Abdominal Aortic Aneurysm52.9%Acute Lymphoblastic Leukemia23.5%Actinic Keratosis11.8%
Open-enrollment share among volume-matched conditions near Cardiogenic Shock

Cardiogenic Shock lists 14 open slots (82% of 17 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Cardiogenic Shock on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Cardiogenic Shock is recruiting above its size-band peers.

    14 of 17 indexed trials (82.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Cardiogenic Shock research.

    Tufts Medical Center accounts for 3 of 17 trials (17.6%). 14 distinct sponsors appear on at least one study for this condition label.

  3. Typical Cardiogenic Shock enrolment sits around 104 participants.

    Median target enrolment is 104 among the 17 trials that report a genuine target (sentinel values excluded). 8 of those (47.1%) plan for fewer than 100 participants.

  4. Cardiogenic Shock splits between interventional and observational designs.

    8 interventional and 9 observational studies make up this index (47.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 22

Open and recent trials

17 total, page 1 of 1

RECRUITING 5,000 participants

Cardiogenic Shock Working Group Registry

Tufts Medical Center

NCT04682483

RECRUITING 3,000 participants

Inova Cardiogenic Shock Registry (INOVA SHOCK)

Inova Health Care Services

NCT03378739

RECRUITING 500 participants

Multi-center Collaborative to Enhance Quality and Outcomes in the Management of Cardiogenic Shock

Stavros G Drakos

NCT05185492

RECRUITING NA 400 participants

Pulmonary Artery Catheter in Cardiogenic Shock Trial

Tufts Medical Center

NCT05485376

RECRUITING 200 participants

Left Ventricular Physiological Effects of Veno-Arterial Extracorporeal Membrane Oxygenation Support During Cardiogenic Shock

University of Minnesota

NCT05426083

RECRUITING NA 144 participants

Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock

Ottawa Heart Institute Research Corporation

NCT05298124

RECRUITING Phase 2 104 participants

Physiology of Unloading VA ECMO Trial

University of Utah

NCT06336655

RECRUITING 60 participants

Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure

Tufts Medical Center

NCT06253104

RECRUITING Phase 2 50 participants

Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System

Stanford University

NCT06080074

RECRUITING NA 40 participants

Hemodynamic Monitoring to Prevent Adverse Events foLlowing cardiOgenic Shock Trial

Inova Health Care Services

NCT04419480

RECRUITING 30 participants

Pre-Emptive LAVA-ECMO for Complex High-Risk TAVR

Atlantic Health System

NCT07309029

RECRUITING NA 25 participants

Augmented Pacing for Shock in the Cardiac Intensive Care Unit

Vanderbilt University Medical Center

NCT06713668

RECRUITING 20 participants

Intra-aortic Balloon Counterpulsation (IABC) Compliance

Thomas Jefferson University

NCT07402018

RECRUITING Early Phase 1 5 participants

Cardiac Power Output in Cardiogenic Shock Patients

University of Chicago

NCT05700617

ACTIVE NOT RECRUITING Phase 1 20 participants

A Safety and Efficacy Trial of Istaroxime for Cardiogenic Shock Stage C

Windtree Therapeutics

NCT05975021

COMPLETED 406 participants

National Cardiogenic Shock Initiative

Henry Ford Health System

NCT03677180

COMPLETED 150 participants

PPCM Observational Study (Peripartum Cardiomyopathy)

Medical College of Wisconsin

NCT04234659

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 2

Named interventions

Most-linked intervention names on Cardiogenic Shock records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Clinical placement of a temporary IMPELLA® mechanical circulatory support device. Device
1 trials
Istaroxime Drug
1 trials
Backup Pacing Rate Change Device
1 trials
Acute Mechanical Circulatory Support Devices Device
1 trials
Inotrope Drug
1 trials
Vasopressor Drug
1 trials
Pulmonary Artery Catheter Device
1 trials
Bivalirudin Drug
1 trials

US sites by state

Facility locations filed on Cardiogenic Shock trials. A trial with sites in several states counts in each.

Virginia 4 trials
Massachusetts 4 trials
Illinois 3 trials
Florida 3 trials
Washington 2 trials
Texas 2 trials
Pennsylvania 2 trials
Oregon 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Cardiogenic Shock page

17 registered trials, 14 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cardiogenic Shock condition card totals 17 registered trials; most-linked intervention Clinical placement of a temporary IMPELLA® mechanical circulatory support device.; top US site state Virginia. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.