Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02035358 · ClinicalTrials.gov registry record · Phase 1
Immunotherapy Study for Metastatic Renal Cell Cancer
A Phase 1 study, sponsored by NewLink Genetics Corporation.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
NCT02035358: Completed Phase 1 study, sponsored by NewLink Genetics Corporation.
NCT02035358 is a Phase 1 study that has completed, run by NewLink Genetics Corporation. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02035358, a Phase 1 study, has completed, sponsored by NewLink Genetics Corporation.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
Study Summary
In this Phase 1 Trial investigators plan to establish the MTD of HyperAcute®-Renal (HAR) immunotherapy in subjects with clinically metastatic renal cell carcinoma.
Primary Outcome
To determine the toxicity (side-effects, dose-limiting toxicity \[DLT\] and maximum tolerated dose \[MDT\]) of administration of HyperAcute®- Renal (HAR) immunotherapy cells administered by intradermal injection into patients with recurrent or refractory, metastatic clear-cell renal cancer.
Interventions
- BIOLOGICAL HyperAcute®-Renal (HAR) Immunotherapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2015-05 |
| Est. Completion | 2021-01-12 |
| Phase | Phase 1 |
What the finished NCT02035358 record still lists
NCT02035358 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 1 intervention - of which HyperAcute®-Renal (HAR) Immunotherapy is the first listed.
NCT02035358 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02035358 about?
NCT02035358 is a clinical study titled "Immunotherapy Study for Metastatic Renal Cell Cancer". In this Phase 1 Trial investigators plan to establish the MTD of HyperAcute®-Renal (HAR) immunotherapy in subjects with clinically metastatic renal cell carcinoma.
What is the current status of trial NCT02035358?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2015-05. Estimated completion is 2021-01-12.
What interventions are being tested in trial NCT02035358?
The interventions under investigation include: HyperAcute®-Renal (HAR) Immunotherapy (BIOLOGICAL).
Who is sponsoring clinical trial NCT02035358?
This trial is sponsored by NewLink Genetics Corporation, which has 31 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02035358's enrollment target sits among peer trials
18 1720th of 2000 higher than 216 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01245179 · 18 participants · Phase 1
Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease
- NCT01999361 · 18 participants · NA
Prevention of de Novo Allosensitization in Islet Transplant Recipients Following Complete Graft Loss
- NCT02359825 · 18 participants · Phase 1
Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function
- NCT02870244 · 18 participants · Phase 1
Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia