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NCT00739609 · ClinicalTrials.gov registry record · Phase 1

IDO Inhibitor Study for Relapsed or Refractory Solid Tumors

A Phase 1 study, sponsored by NewLink Genetics Corporation.

Terminated
Registry status
Phase 1
Development phase
17
Enrollment target

NCT00739609: Clinical Trial Phase 1 study, sponsored by NewLink Genetics Corporation.

NCT00739609 is a Phase 1 study that was terminated before completion, run by NewLink Genetics Corporation. The registered enrollment target is 17 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00739609, a Phase 1 study, was terminated before completion, sponsored by NewLink Genetics Corporation.

TERMINATED
Registry status
Phase 1
Development phase
17 participants
Enrollment target

Study Summary

This study provides an early evaluation of an entirely new class of small molecule agents directed at disruption or elimination of tumor tolerance, a phenomenon now demonstrated to be involved in the growth of many solid tumors.

Interventions

  • DRUG 1-methyl-D-tryptophan

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2008-08
Est. Completion 2012-10
Phase Phase 1
NewLink Genetics Corporation

31 total trials

Why NCT00739609 stopped before completion

NCT00739609 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (72% lower).

The record links to 0 conditions, and to 1 intervention - of which 1-methyl-D-tryptophan is the first listed.

NCT00739609 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00739609 about?

NCT00739609 is a clinical study titled "IDO Inhibitor Study for Relapsed or Refractory Solid Tumors". This study provides an early evaluation of an entirely new class of small molecule agents directed at disruption or elimination of tumor tolerance, a phenomenon now demonstrated to be involved in the growth of many solid tumors.

What is the current status of trial NCT00739609?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 17 participants. The study started on 2008-08. Estimated completion is 2012-10.

What interventions are being tested in trial NCT00739609?

The interventions under investigation include: 1-methyl-D-tryptophan (DRUG).

Who is sponsoring clinical trial NCT00739609?

This trial is sponsored by NewLink Genetics Corporation, which has 31 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00739609's enrollment target sits among peer trials

17 1785th of 2000 higher than 215 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00739609, the US trial registry maintained by the National Library of Medicine. NCT00739609 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.