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NCT02052648 · ClinicalTrials.gov registry record · Phase 1
Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors
A Phase 1 study, sponsored by NewLink Genetics Corporation.
- Completed
- Registry status
- Phase 1
- Development phase
- 160
- Enrollment target
NCT02052648: Completed Phase 1 study, sponsored by NewLink Genetics Corporation.
NCT02052648 is a Phase 1 study that has completed, run by NewLink Genetics Corporation. The registered enrollment target is 160 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (167% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02052648, a Phase 1 study, has completed, sponsored by NewLink Genetics Corporation.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 160 participants
- Enrollment target
Study Summary
In this study, investigators will conduct a phase I/II trial in recurrent (temozolomide resistant) glioma patients. The overall goal of this study is to provide a foundation for future studies with indoximod tested in newly diagnosed glioblastoma patients with radiation and temozolomide, or in combination with vaccine therapies.
Primary Outcome
Number of RLTs observed in each dose level.
Interventions
- DRUG Bevacizumab
- DRUG Temozolomide
- RADIATION Stereotactic Radiation
- DRUG Indoximod
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 160 participants |
| Start Date | 2014-03 |
| Est. Completion | 2019-06-20 |
| Phase | Phase 1 |
What the finished NCT02052648 record still lists
NCT02052648 is an interventional study that assigns participants to a tested intervention. The registered 160 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (167% higher).
The record links to 0 conditions, and to 4 interventions - of which Bevacizumab is the first listed.
NCT02052648 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02052648 about?
NCT02052648 is a clinical study titled "Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors". In this study, investigators will conduct a phase I/II trial in recurrent (temozolomide resistant) glioma patients. The overall goal of this study is to provide a foundation for future studies with indoximod tested in newly diagnosed glioblastoma patients with radiation and temozolomide, or in combi...
What is the current status of trial NCT02052648?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 160 participants. The study started on 2014-03. Estimated completion is 2019-06-20.
What interventions are being tested in trial NCT02052648?
The interventions under investigation include: Bevacizumab (DRUG), Temozolomide (DRUG), Stereotactic Radiation (RADIATION), Indoximod (DRUG).
Who is sponsoring clinical trial NCT02052648?
This trial is sponsored by NewLink Genetics Corporation, which has 31 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02052648's enrollment target sits among peer trials
160 340th of 2000 higher than 1,655 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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