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NCT00011284 · ClinicalTrials.gov registry record
Mechanisms of Inflammatory Liver Injury
A clinical trial of Liver Diseases, sponsored by National Institute of Environmental Health Sciences (NIEHS).
- Completed
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT00011284 is a study of Liver Diseases that has completed, run by National Institute of Environmental Health Sciences (NIEHS). The registered enrollment target is 50 participants, below the 61,157-participant average among 33 other Liver Diseases trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.
The verdict
NCT00011284, a study of Liver Diseases, has completed, sponsored by National Institute of Environmental Health Sciences (NIEHS).
- COMPLETED
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
White blood cells can cause liver damage if they inappropriately accumulate in the liver in large numbers. Such an event can occur if an individual's blood is exposed to endotoxin, a substance released from the cell walls of many species of bacteria. The purpose of this study is to isolate neutrophils, an important white blood cell, from the blood of normal volunteers, and put them in tissue culture with isolated liver cells. The experiments will determine how endotoxin can increase the ability of neutrophils to damage liver cells. All studies supported by this grant will be done with isolated cells in tissue culture. This experimental model will reveal possible mechanisms that can in the future be evaluated in human diseases such as bacterial sepsis.
Conditions Studied
Study Locations (1)
Texas
- Baylor College of Medicine - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Est. Completion | 2001-11 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00011284
The ClinicalTrials.gov registry entry for NCT00011284 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 61,157-participant average among 33 other Liver Diseases trials with a reported enrollment target (100% lower). The listed sponsor is National Institute of Environmental Health Sciences (NIEHS), which has 145 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Liver Diseases appearing as the primary indexed condition, and to 0 interventions.
NCT00011284 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT00011284 about?
NCT00011284 is a clinical study titled "Mechanisms of Inflammatory Liver Injury". White blood cells can cause liver damage if they inappropriately accumulate in the liver in large numbers. Such an event can occur if an individual's blood is exposed to endotoxin, a substance released from the cell walls of many species of bacteria. The purpose of this study is to isolate neutrophi...
What is the current status of trial NCT00011284?
This trial is currently completed. The enrollment target is 50 participants. Estimated completion is 2001-11.
What conditions does trial NCT00011284 study?
This clinical trial studies the following conditions: Liver Diseases.
Who is sponsoring clinical trial NCT00011284?
This trial is sponsored by National Institute of Environmental Health Sciences (NIEHS), which has 145 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00011284 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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