Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00011284 · ClinicalTrials.gov registry record
Mechanisms of Inflammatory Liver Injury
A clinical trial of Liver Diseases, sponsored by National Institute of Environmental Health Sciences (NIEHS).
- Completed
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT00011284: Completed study of Liver Diseases, sponsored by National Institute of Environmental Health Sciences (NIEHS).
NCT00011284 is a study of Liver Diseases that has completed, run by National Institute of Environmental Health Sciences (NIEHS). The registered enrollment target is 50 participants, below the 61,157-participant average among 33 other Liver Diseases trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00011284, a study of Liver Diseases, has completed, sponsored by National Institute of Environmental Health Sciences (NIEHS).
- COMPLETED
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
White blood cells can cause liver damage if they inappropriately accumulate in the liver in large numbers. Such an event can occur if an individual's blood is exposed to endotoxin, a substance released from the cell walls of many species of bacteria. The purpose of this study is to isolate neutrophils, an important white blood cell, from the blood of normal volunteers, and put them in tissue culture with isolated liver cells. The experiments will determine how endotoxin can increase the ability of neutrophils to damage liver cells. All studies supported by this grant will be done with isolated cells in tissue culture. This experimental model will reveal possible mechanisms that can in the future be evaluated in human diseases such as bacterial sepsis.
Conditions Studied
Study Locations (1)
Texas
- Baylor College of Medicine - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Est. Completion | 2001-11 |
What the finished NCT00011284 record still lists
NCT00011284 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 61,157-participant average among 33 other Liver Diseases trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Liver Diseases appearing as the primary indexed condition, and to 0 interventions.
NCT00011284 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT00011284 about?
NCT00011284 is a clinical study titled "Mechanisms of Inflammatory Liver Injury". White blood cells can cause liver damage if they inappropriately accumulate in the liver in large numbers. Such an event can occur if an individual's blood is exposed to endotoxin, a substance released from the cell walls of many species of bacteria. The purpose of this study is to isolate neutrophi...
What is the current status of trial NCT00011284?
This trial is currently completed. The enrollment target is 50 participants. Estimated completion is 2001-11.
What conditions does trial NCT00011284 study?
This clinical trial studies the following conditions: Liver Diseases.
Who is sponsoring clinical trial NCT00011284?
This trial is sponsored by National Institute of Environmental Health Sciences (NIEHS), which has 145 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00011284 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Liver Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00011284's enrollment target sits among peer trials
50 23rd of 33 higher than 11 of 33 other Liver Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Liver Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Veteran-Centered Care for Advanced Liver Disease (Vet-CALD)
RECRUITING · NA
-
Enhancing Alcohol Treatment Engagement in Associated Liver Disease (ALD) Patients
RECRUITING · NA
-
MAsS Scan as a Predictor of Morbidity and Mortality in Patients With Liver Disease
RECRUITING
-
The Microbiota Augmentation to Reestablish Commensal Organisms (MARCO) Trial
RECRUITING · Phase 1
-
Genetic Collection Protocol
RECRUITING
-
Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00200889 · 50 participants · Early Phase 1
Mapping Auricular Vagus Nerve Circuitry
- NCT00409435 · 50 participants · Phase 2
A Study of Pyridostigmine in Postural Tachycardia Syndrome
- NCT01202305 · 50 participants
The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies
- NCT01225913 · 50 participants · Phase 4
Mechanism(s) of Airflow Limitation During Exacerbation of Asthma