National Institute of Dental and Craniofacial Research (NIDCR)
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, National Institute of Dental and Craniofacial Research (NIDCR) sits in the top decile of US sponsors by registered trial count (#259 of 15,742 sponsors by registered trial count).
National Institute of Dental and Craniofacial Research (NIDCR): 91 sponsored US clinical trials, 11 recruiting.
National Institute of Dental and Craniofacial Research (NIDCR) sponsors 91 registered US clinical trials on ClinicalTrials.gov, 11 of them currently recruiting, and 70 completed. 2 of these trials are in Phase 3-4 (later-stage) and 41 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sjogren's Syndrome, with 6 trials.
Top-decile sponsor footprint
National Institute of Dental and Craniofacial Research (NIDCR) ranks in the top decile of sponsors by registered trial count (#259 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
70 of 78 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
91 total, page 1 of 2
Safety and Efficacy of PTH-IA
NCT07541209
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren Disease
NCT07281456
Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls
NCT03602599
Natural History of Craniofacial Anomalies and Developmental Growth Variants
NCT02639312
Characterization of Diseases With Salivary Gland Involvement
NCT02327884
Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal
NCT01805869
Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)
NCT01568697
The Pathogenesis and Natural History of Sjogren's Disease
NCT01425892
Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer
NCT00804154
A Natural History Study of Bone and Mineral Disorders
NCT00024804
Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome
NCT00001727
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrome
NCT04496960
Denosumab Treatment for Fibrous Dysplasia
NCT03571191
PTH-independent Effects of Encaleret
NCT05735015
Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous Dysplasia
NCT05509595
Study of Denosumab for Prevention of Skeletal Disease Progression in Children With Fibrous Dysplasia
NCT05419050
Transmissibility and Viral Load of SARS-CoV-2 in Oral Secretions
NCT04348240
BGJ398 for the Treatment of Tumor-Induced Osteomalacia
NCT03510455
Oral Health Needs Assessment of Sjogren s Syndrome and Salivary Gland Dysfunction Cohorts and Healthy Volunteers Evaluating Oral Health Disparities as Determinants of Oral Health in a High-Risk Population
NCT03327870
Bacterial Arrangement on the Teeth
NCT01712672
Cinacalcet for Fibroblast Growth Factor 23 (FGF23)-Mediated Hypophosphatemia (Hypophosphatemic Rickets)
NCT01748812
Dexamethasone Irrigation of the Parotid Glands in Primary Sjögren's Syndrome Subjects
NCT01316770
Rapamycin Therapy in Head and Neck Squamous Cell Carcinoma
NCT01195922
The Molecular Anatomy of Oral Wound Healing
NCT01078467
Collection of Tissue Specimens for Analysis and Establishment of Cell Cultures
NCT00802607
Evaluation of the Role of the Autonomic Nervous System in Sj(SqrRoot)(Delta)Gren s Syndrome
NCT00565526
Procurement of Tissue Samples for Cell Cultures and Analyses
NCT00435877
Effects of PTH Replacement on Bone in Hypoparathyroidism
NCT00395538
Effect of AdhAQP1 on Salivary Flow in Patients Treated With Radiation for Head and Neck Cancer
NCT00372320
Physiologic Regulation of FGF-23
NCT00356512
Pilot Study of Raptiva to Treat Sjogren's Syndrome
NCT00344448
Diagnosis, Evaluation and Treatment of Patients in Need of Third Molar Removal
NCT00316485
Dexamethasone to Treat Oral Lichen Planus
NCT00111072
Genes Associated With Hereditary and Drug-Induced Gingival Overgrowth
NCT00104026
Hydroxychloroquine vs. Clobetasol Rinse to Treat Oral Lichen Planus
NCT00102557
Stereo Photogrammetry Imaging in Normal Volunteers and Patients With Head and Facial Malformations
NCT00100529
Salivary Proteins in Disease and Health
NCT00100204
Catheterization to Locate Mesenchymal Tumors in Patients With Tumor-Induced Osteomalacia or Oncogenic Osteomalacia
NCT00099762
Collection of Dental Plaque and Saliva for Studies of Bacterial Colonization of Teeth
NCT00098267
Clinical Research Core Dental Screening Protocol
NCT00090818
Levels of Bisphenol A in Urine and Saliva Following Placement of Composite Restorations
NCT00339339
Capsaicin to Control Pain Following Third Molar Extraction
NCT00088686
Synvisc to Treat Osteoarthritis of the Temporomandibular Joint
NCT00078351
Pain Pathways in the Brain
NCT00078364
Prostanoid Levels After Medication to Prevent Pain Following Third Molar (Wisdom Tooth) Extraction
NCT00078104
Studying Phosphorus Metabolism
NCT00066183
Chemical and Genetic Effects of the Experimental Anti-Cancer Drugs in Cheek Cells in Cancer Patients
NCT00055380
Rofecoxib and Bupivacaine to Prevent Pain After Third Molar (Wisdom Tooth) Extraction
NCT00050362
Study of Oral Bacteria in Patients With Dry Mouth
NCT00048685
Magnets in the Treatment of Sciatica
NCT00044109
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 9 |
| Phase 2 | 32 |
| Phase 3 | 2 |
Therapeutic Areas
What is open in the National Institute of Dental and Craniofacial Research (NIDCR) pipeline
11 recruiting of 91 indexed (12% open); 70 completed (77%).
Phase mix: 2 late (III/IV) vs 41 early (I/II) (early-phase heavy).
Top condition: Sjogren's Syndrome (6 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
National Institute of Dental and Craniofacial Research (NIDCR): open-pipeline peers nationwide
Peers matched on 91 registered trials and 12% open enrollment, not the therapeutic-area sidebar.
National Institute of Dental and Craniofacial Research (NIDCR) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 91 trials (± recruiting share)
- University of Central Florida · 91 trials · 42% recruiting
- Children's National Research Institute · 92 trials · 38% recruiting
- Drexel University · 92 trials · 16% recruiting
- Loyola University · 92 trials · 13% recruiting
Sponsors near 12% open enrollment (± trial volume)
- East Carolina University · 12% recruiting · 58 trials
- Antonios Likourezos · 12% recruiting · 33 trials
- Oregon State University · 12% recruiting · 33 trials
- University of Massachusetts, Amherst · 12% recruiting · 33 trials
Related
What to do with this National Institute of Dental and Craniofacial Research (NIDCR) page
91 registered trials is a research-attention snapshot, not an endorsement of National Institute of Dental and Craniofacial Research (NIDCR) or any single study.
- 11 of National Institute of Dental and Craniofacial Research (NIDCR)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Sjogren's Syndrome is the condition National Institute of Dental and Craniofacial Research (NIDCR) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Sjogren's Syndrome trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
National Institute of Dental and Craniofacial Research (NIDCR) pipeline card: 91 registered trials from official public datasets.Report a data error.