Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Sciatica: early-phase trial registry
1 of 7 indexed Sciatica trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,497 of 28,707 conditions by registered trial count.
7 US clinical trials · 1 currently recruiting · #2,497 of 28,707 conditions by registered trial count
Sciatica: 7 US clinical trials tracked, 1 recruiting.
Sciatica is the subject of 7 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Dental and Craniofacial Research (NIDCR), running 2 of these trials.
Enrollment posture brief
Registry condition sciatica
OPEN 1 | RECR 14% | LATE 1 | EARLY 5 | RANK #2497 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Adverse Drug Events (14% recruiting · 7 trials)
Sciatica lists 1 open slots (14% of 7 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Sciatica on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Sciatica is recruiting below its size-band peers.
1 of 7 indexed trials (14.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Sciatica research.
National Institute of Dental and Craniofacial Research (NIDCR) accounts for 2 of 7 trials (28.6%). 6 distinct sponsors appear on at least one study for this condition label.
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Most Sciatica trials plan to enrol fewer than 100 people.
Median target enrolment is 75 among the 7 trials that report a genuine target (sentinel values excluded). 6 of those (85.7%) plan for fewer than 100 participants.
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Sciatica research is mostly interventional.
7 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
7 total, page 1 of 1
A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE
National University of Natural Medicine
NCT07125027
The Efficacy of Oral Steroids in the Treatment of Acute Sciatica
Kaiser Permanente
NCT00317447
Study to Evaluate the Safety and Efficacy of Placulumab (CEP-37247) Administered by the Transforaminal Epidural Route for the Treatment of Patients With Lumbosacral Radicular Pain Associated With Disk Herniation
Cephalon
NCT01240876
Pain Treatment for Sciatica
National Institute of Dental and Craniofacial Research (NIDCR)
NCT00009672
Magnets in the Treatment of Sciatica
National Institute of Dental and Craniofacial Research (NIDCR)
NCT00044109
A Study of the Pharmacokinetics, Safety, and Preliminary Efficacy of MDT-15 in Subjects With Lumbosacral Radiculopathy
Medtronic Spinal and Biologics
NCT01917825
Efficacy of Epidural Etanercept in the Treatment of Sciatica
Johns Hopkins University
NCT00364572
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 3 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Sciatica records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Sciatica trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Sciatica page
7 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 1 Sciatica trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Institute of Dental and Craniofacial Research (NIDCR) sponsors the most Sciatica trials on record, review their full trial history before evaluating a specific study. See National Institute of Dental and Craniofacial Research (NIDCR)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Sciatica condition card totals 7 registered trials; most-linked intervention MDT-15; top US site state Oregon. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.