National Institute of Allergy and Infectious Diseases (NIAID)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Allergy and Infectious Diseases (NIAID) sits in the top decile of US sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count).

2,006 total trials 155 currently recruiting 1642 completed early-phase tilt top decile by trial count

National Institute of Allergy and Infectious Diseases (NIAID): 2,006 sponsored US clinical trials, 155 recruiting.

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Top-decile sponsor footprint

National Institute of Allergy and Infectious Diseases (NIAID) ranks in the top decile of sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 68/100

1,642 of 1,802 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

2,006 total, page 27 of 41

COMPLETED Phase 2

9-valent CRM 197 Pneumococcal

NCT00133549

COMPLETED Phase 2

A Comparison of the Effectiveness, Safety, and Tolerability of Two Different Hepatitis C Treatments in Patients Infected With Both HIV and Hepatitis C Virus (HCV)

NCT00008463

COMPLETED Phase 2

Modified Stem Cell Transplantation Procedure for Treating Chronic Granulomatous Disease

NCT00006417

COMPLETED Phase 2

A Study of HIV-Disease Development in Aging

NCT00006144

COMPLETED Phase 1

Pharmacokinetics of Antiretroviral Agents in HIV-1 Infected Pregnant Women

NCT00006320

COMPLETED Phase 3

Long Term Treatment of Herpes Simplex Encephalitis (HSE) With Valacyclovir

NCT00031486

COMPLETED Phase 3

Preventing Cytomegalovirus (CMV) Organ Damage With Valganciclovir in People With HIV

NCT00006145

COMPLETED Phase 2

Half-Dose Flu Vaccine Study in Healthy Adults

NCT00006146

COMPLETED

Immune Function of Infants With HIV

NCT00073229

COMPLETED

Effects of Long-Term Treatment With Valaciclovir (Valtrex) on Epstein-Barr Virus

NCT00005924

COMPLETED

Genetic Factors in Atherosclerosis

NCT00359307

COMPLETED

The Effect of Anti-HIV Treatment on Body Characteristics of HIV-Infected Children

NCT00006064

COMPLETED

Comparison of Immune Response to Booster Vaccines in Blood Transplant Patients and Healthy Volunteers

NCT00005907

COMPLETED

Learning and Behavior Problems in Children With Chronic Granulomatous Disease and Related Disorders

NCT00005933

COMPLETED Phase 3

Azithromycin/Bicillin Syphilis

NCT00031499

COMPLETED Phase 1

Safety and Anti-HIV Activity of Capravirine Alone and in Combination With Other Anti-HIV Drugs

NCT00005673

COMPLETED

Analysis of HIV Genetic Variation in Patients Before Beginning Highly Active Antiretroviral Therapy

NCT00009256

COMPLETED NA

Antibody and Delayed Cyclosporine Versus Initial Cyclosporine Alone in Patients Receiving Kidney Transplants

NCT00007787

COMPLETED

Comparison of Immune Response in Normal Volunteers and Patients With Helminth Infections

NCT00004996

COMPLETED

Network on Antimicrobial Resistance in Staphylococcus Aureus

NCT00341913

COMPLETED Phase 3

An International Study to Evaluate Recombinant Interleukin-2 in HIV Positive Patients Taking Anti-retroviral Therapy

NCT00004978

COMPLETED

A Test of Behavioral Intervention for Women at High Risk for HIV Infection

NCT00006440

COMPLETED Phase 2

Comparison of Treatments to Maintain Disease Remission in Patients With Wegener's Granulomatosis and Related Vasculitis Syndromes

NCT00004567

COMPLETED NA

The Effects of Anti-HIV Therapy on the Immune Systems of Children and Young Adults Infected With HIV

NCT00004735

COMPLETED Phase 1

Once-Daily Drug Regimen for HIV-Infected Patients

NCT00001968

COMPLETED

Comparison of Two Test Methods-NASBA and Antigenemia-for Detecting Cytomegalovirus Infection

NCT00001976

COMPLETED Phase 4

Intermittent Versus Continuous Medication in the Treatment of HIV

NCT00001967

COMPLETED Phase 2

Effectiveness of the Early Addition of Abacavir to an Anti-HIV Drug Combination

NCT00001132

TERMINATED Phase 3

A Study To Test An Anti-Rejection Therapy After Kidney Transplantation

NCT00000936

COMPLETED NA

Effects on the Immune System of Anti-HIV Drugs in Patients Recently Infected With HIV

NCT00001119

COMPLETED Phase 1

Effect of an Anti-Inflammatory Drug on Gut Mucosa in HIV Infected Patients

NCT00069498

COMPLETED

The Biology of HIV Transmission

NCT00001092

COMPLETED

Outcomes of Anti-HIV Therapy During Early HIV Infection

NCT00001093

COMPLETED Phase 2

Study of Immune Responses and Safety of Recombinant Human CD40 Ligand in Patients With X-Linked Hyper-IgM Syndrome

NCT00001145

COMPLETED

A Study to Monitor Patients With Primary or Early HIV Infection

NCT00000911

COMPLETED

New Techniques for Using a Saline Wash as a Diagnostic Tool for Pneumocystis Pneumonia

NCT00342589

COMPLETED

Brain Tissue Swelling and Seizure Activity in Inactive Cysticercosis

NCT00001912

COMPLETED Phase 3

Acyclovir Herpes Simplex Virus (HSV) Skin, Eye, and Mouth

NCT00031447

COMPLETED

A Study to Monitor the Health of Participants in HIVNET 014 Who Become Infected With HIV-1

NCT00001121

COMPLETED NA

Effect of Anti-HIV Therapy (HAART) on HIV Levels in the Lungs and on Lung Cell Inflammation in HIV-Infected Patients

NCT00001110

COMPLETED

Mechanisms of Allergen Immunotherapy

NCT00001910

COMPLETED Phase 1

Interleukin-12 in the Treatment of Severe Nontuberculous Mycobacterial Infections

NCT00001911

COMPLETED

Treatment of Acute HIV Infection to Preserve Immune Function

NCT00055094

COMPLETED

T Cell Cytokine Changes During IL-4 Receptor Treatment for Asthma

NCT00001908

COMPLETED Phase 2

Phase II Efficacy Study of Aerosolized Recombinant Human IL-4 Receptor in Asthma

NCT00001909

COMPLETED Phase 2

A Study to Evaluate High Protein Supplementation in HIV-Positive Patients With Stable Weight Loss

NCT00000925

COMPLETED Phase 2

Five-Drug Anti-HIV Treatment Followed by Treatment Interruption in Patients Who Have Recently Been Infected With HIV

NCT00000940

COMPLETED Phase 1

Safety and Immunogenicity of a Vaccine for Cutaneous Leishmaniasis Using Recombinant Human Interleukin-12 and Aluminum Hydroxide Gel as Adjuvants

NCT00001906

COMPLETED Phase 4

Prevention of RSV Infections in Bone Marrow Transplant Recipients

NCT00001903

COMPLETED Phase 2

Interferon Gamma to Treat Leukocyte Adhesion Deficiency Type I

NCT00001905

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What is open in the National Institute of Allergy and Infectious Diseases (NIAID) pipeline

155 recruiting of 2,006 indexed (8% open); 1,642 completed (82%).

Phase mix: 177 late (III/IV) vs 1,291 early (I/II) (early-phase heavy).

Top condition: HIV Infections (195 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Allergy and Infectious Diseases (NIAID): open-pipeline peers nationwide

Peers matched on 2,006 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 5%10%15%20% Total trials Recruiting share National Institute of Allergy and Infectious Diseases (NIAID)Massachusetts General HospitalMemorial Sloan Kettering Cancer CenterPfizerStanford UniversityAlumisAndrei IagaruBioXcel TherapeuticsCorporal Michael J. Crescenz VA Medical Center
National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 2,006 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Allergy and Infectious Diseases (NIAID) page

2,006 registered trials is a research-attention snapshot, not an endorsement of National Institute of Allergy and Infectious Diseases (NIAID) or any single study.

  • 155 of National Institute of Allergy and Infectious Diseases (NIAID)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infections is the condition National Institute of Allergy and Infectious Diseases (NIAID) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infections trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Allergy and Infectious Diseases (NIAID) pipeline card: 2,006 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.