National Institute of Allergy and Infectious Diseases (NIAID)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Allergy and Infectious Diseases (NIAID) sits in the top decile of US sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count).

2,006 total trials 155 currently recruiting 1642 completed early-phase tilt top decile by trial count

National Institute of Allergy and Infectious Diseases (NIAID): 2,006 sponsored US clinical trials, 155 recruiting.

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Top-decile sponsor footprint

National Institute of Allergy and Infectious Diseases (NIAID) ranks in the top decile of sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 68/100

1,642 of 1,802 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

2,006 total, page 26 of 41

COMPLETED Phase 2

Therapeutic HIV Vaccine and Interleukin-2 to Increase the Immune System's Response to HIV

NCT00056797

COMPLETED

Screening Protocol for HIV Vaccine Studies

NCT00031304

COMPLETED Phase 2

The Impact of HAART on Response to Hepatitis C Treatment in Patients Taking Peginterferon Alpha-2b and Ribavirin

NCT00031343

COMPLETED Phase 2

Stem Cell Transplantation to Treat Leukocyte Adhesion Deficiency

NCT00031005

COMPLETED

Effects of Two Anti-HIV Drug Regimens on HIV Transmission Risk Behavior Among SMART Study Participants

NCT00386035

COMPLETED

Effects of Two Anti-HIV Drug Regimens on Quality of Life and Health Care Use Among SMART Study Participants

NCT00385632

COMPLETED Phase 1

Stem Cell Gene Therapy to Treat X-Linked Severe Combined Immunodeficiency (XSCID)

NCT00028236

COMPLETED

Immune Responses to HIV in Blood Cells in HIV-Infected and HIV-Uninfected Volunteers

NCT00027482

COMPLETED Phase 2

Rituximab to Treat Hepatitis C-Associated Cryoglobulinemic Vasculitis

NCT00029107

COMPLETED NA

Treatment of Multiple Sclerosis With Copaxone and Albuterol

NCT00039988

COMPLETED Phase 1

G-CSF to Treat Crohn's Disease

NCT00025805

COMPLETED

Influenza Vaccine in HIV Infection: Immune Response and Effect on Viral Load

NCT00025922

COMPLETED Phase 3

Intermittent vs. Continuous HAART to Treat Chronic HIV Infection

NCT00025909

COMPLETED

Impact of Gender on Patients

NCT00170560

COMPLETED

Funguria in Hospitalized Patients

NCT00138502

COMPLETED

Neonatal CMV-Ganciclovir Follow-up Study

NCT00031421

TERMINATED Phase 2

Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia

NCT00034528

COMPLETED Phase 3

Treatment of Chronic Granulomatous Disease With Allogeneic Stem Cell Transplantation Versus Standard of Care

NCT00023192

COMPLETED Phase 3

Lamivudine and Adefovir to Treat Chronic Hepatitis B Infection in People With and Without HIV Infection

NCT00023153

COMPLETED Phase 1

Safety and Effectiveness of Emtricitabine, Efavirenz, and Didanosine in HIV Infected Children Who Have Taken Few or No Anti-HIV Drugs

NCT00016718

COMPLETED Phase 2

A Randomized, Double-Blinded, Placebo-Controlled, Phase II Inhaled Interferon Gamma-1b and Antimycobacterials to Treat Pulmonary Mycobacterium Avium Complex Infections

NCT00021567

COMPLETED Phase 2

Pleconaril Enteroviral Sepsis Syndrome

NCT00031512

COMPLETED NA

Depo-Medroxyprogesterone Acetate (DMPA, Depo-Provera) Use With Certain Anti-HIV Drugs in HIV-Infected Women

NCT00016601

COMPLETED Phase 2

Anti-Interleukin-5 Antibody to Treat Hypereosinophilic Syndrome

NCT00017862

COMPLETED Phase 2

Peginterferon Alpha-2b And Ribavirin to Treat Hepatitis C in HIV-Infected Patients

NCT00018031

COMPLETED

Nerve Damage in Patients With HIV Infection Who Have Been Treated With Anti-HIV Drugs

NCT00017771

TERMINATED

Identification of Viruses Associated With Diseases of Unknown Cause

NCT00359268

COMPLETED Phase 2

Studies of Influenza Vaccine and Tetanus-Pneumococcal Vaccine in HIV-infected Patients Receiving Interleukin-2

NCT00050726

COMPLETED

Immune System and Gut Abnormalities in Patients With Common Variable Immunodeficiency With and Without Gastrointestinal Symptoms

NCT00015431

COMPLETED Phase 2

Islet Transplantation for Type 1 Diabetes

NCT00014911

COMPLETED Phase 2

Using the Drug Thalidomide to Stimulate T Cells in HIV-Infected People

NCT00053430

COMPLETED Phase 3

Emergency Use of Voriconazole in Patients With Life-Threatening Invasive Fungal Infections

NCT00015665

COMPLETED Phase 1

Pyrimethamine and Sulfadoxine for Treatment of Autoimmune Lymphoproliferative Syndrome

NCT00013689

COMPLETED NA

Drug Interactions of Amprenavir and Efavirenz, in Combination With a Second Protease Inhibitor, in HIV-Negative Volunteers

NCT00005762

COMPLETED

Racial Difference in HCV/Host Interactions

NCT00071916

COMPLETED Phase 2

Adefovir Dipivoxil to Treat Hepatitis B in HIV-Infected Patients

NCT00013702

COMPLETED Phase 2

HIV Maintenance Therapy With T-20 During HAART Interruption

NCT00013884

COMPLETED Phase 1

Vaccine (ALVAC-HIV vCP1452) Use and Intermittent Withdrawal of Anti-HIV Drugs in Patients With HIV

NCT00011011

COMPLETED NA

Pediatric Kidney Transplant Without Calcineurin Inhibitors

NCT00023231

COMPLETED Phase 1

Anti-CD20 in Systemic Lupus Erythematosus

NCT00036491

COMPLETED

Effects of Storage on Lactate in Blood Samples

NCT00011050

COMPLETED Phase 1

HIV-1 Vaccine Test in Uninfected Adult Volunteers

NCT00009685

TERMINATED Phase 2

Steroid Withdrawal in Pediatric Kidney Transplant Recipients

NCT00023244

COMPLETED Phase 1

Monoclonal Antibody Treatment of Crohn's Disease

NCT00007163

TERMINATED NA

Assessing Abuse Potential of Parenteral Buprenorphine/Naloxone in Non-Dependent Opioid Abusers

NCT00134875

COMPLETED

Study of Tests to Evaluate Effectiveness of Anti-HIV Drugs

NCT00006494

COMPLETED

The Effects of Combination Anti-HIV Medication on Human Papillomavirus (HPV) in HIV-Infected Women

NCT00006444

COMPLETED Phase 1

Therapeutic Vaccination Followed by Treatment Interruption in HIV Infected Patients

NCT00058734

COMPLETED Phase 1

Atazanavir Used in Combination With Other Anti-HIV Drugs in HIV-Infected Infants, Children, and Adolescents

NCT00006604

COMPLETED

HIV in Specific Parts of the Body of Patients Who Are Changing or Starting Potent Anti-HIV Drugs

NCT00007488

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What is open in the National Institute of Allergy and Infectious Diseases (NIAID) pipeline

155 recruiting of 2,006 indexed (8% open); 1,642 completed (82%).

Phase mix: 177 late (III/IV) vs 1,291 early (I/II) (early-phase heavy).

Top condition: HIV Infections (195 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Allergy and Infectious Diseases (NIAID): open-pipeline peers nationwide

Peers matched on 2,006 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 5%10%15%20% Total trials Recruiting share National Institute of Allergy and Infectious Diseases (NIAID)Massachusetts General HospitalMemorial Sloan Kettering Cancer CenterPfizerStanford UniversityAlumisAndrei IagaruBioXcel TherapeuticsCorporal Michael J. Crescenz VA Medical Center
National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 2,006 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Allergy and Infectious Diseases (NIAID) page

2,006 registered trials is a research-attention snapshot, not an endorsement of National Institute of Allergy and Infectious Diseases (NIAID) or any single study.

  • 155 of National Institute of Allergy and Infectious Diseases (NIAID)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infections is the condition National Institute of Allergy and Infectious Diseases (NIAID) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infections trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Allergy and Infectious Diseases (NIAID) pipeline card: 2,006 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.