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NCT02021968 · ClinicalTrials.gov registry record · Phase 1
Evaluating the Safety and Effectiveness of a Dengue Virus Vaccine in Healthy Adults
A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
NCT02021968: Completed Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
NCT02021968 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 48 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02021968, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
Study Summary
Dengue viruses can cause dengue illness ranging from a mild illness to life-threatening disease. The purpose of this study is to evaluate the protective effectiveness of a dengue virus vaccine in healthy adults.
Primary Outcome
Participants will receive rDEN2∆30-7169 at Day 180. Viremia caused by rDEN2∆30-7160 will be measured through Day 196. Blood samples will be obtained from all participants on Days 180, 182, 184, 186, 188, 190, 192, 194, and 196, and the titer of rDEN2∆20-7169 will be determined.
Interventions
- BIOLOGICAL Placebo
- BIOLOGICAL rDEN2∆30-7169
- BIOLOGICAL TetraVax-DV-TV003
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2013-11 |
| Est. Completion | 2015-12 |
| Phase | Phase 1 |
What the finished NCT02021968 record still lists
NCT02021968 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT02021968 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02021968 about?
NCT02021968 is a clinical study titled "Evaluating the Safety and Effectiveness of a Dengue Virus Vaccine in Healthy Adults". Dengue viruses can cause dengue illness ranging from a mild illness to life-threatening disease. The purpose of this study is to evaluate the protective effectiveness of a dengue virus vaccine in healthy adults.
What is the current status of trial NCT02021968?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2013-11. Estimated completion is 2015-12.
What interventions are being tested in trial NCT02021968?
The interventions under investigation include: Placebo (BIOLOGICAL), rDEN2∆30-7169 (BIOLOGICAL), TetraVax-DV-TV003 (BIOLOGICAL).
Who is sponsoring clinical trial NCT02021968?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02021968's enrollment target sits among peer trials
48 1025th of 2000 higher than 948 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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