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NCT02186626 · ClinicalTrials.gov registry record · Phase 1

Evaluating the Safety and Immunogenicity of a Live Attenuated West Nile Virus Vaccine for West Nile Encephalitis in Adults 50 to 65 Years of Age

A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
28
Enrollment target

NCT02186626: Completed Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT02186626 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 28 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02186626, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
28 participants
Enrollment target

Study Summary

West Nile virus (WNV) is considered an emerging virus in the United States, and infection can lead to severe illness in older adults. This study will evaluate the safety of and immune response to a live West Nile virus vaccine (WN/DEN4Δ30) for the prevention of West Nile encephalitis in adults 50 to 65 years old.

Primary Outcome

As classified by both intensity and severity through active and passive surveillance

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL WN/DEN4Δ30 Vaccine

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2014-02
Est. Completion 2016-07
Phase Phase 1

What the finished NCT02186626 record still lists

NCT02186626 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (53% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02186626 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02186626 about?

NCT02186626 is a clinical study titled "Evaluating the Safety and Immunogenicity of a Live Attenuated West Nile Virus Vaccine for West Nile Encephalitis in Adults 50 to 65 Years of Age". West Nile virus (WNV) is considered an emerging virus in the United States, and infection can lead to severe illness in older adults. This study will evaluate the safety of and immune response to a live West Nile virus vaccine (WN/DEN4Δ30) for the prevention of West Nile encephalitis in adults 50 to...

What is the current status of trial NCT02186626?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2014-02. Estimated completion is 2016-07.

What interventions are being tested in trial NCT02186626?

The interventions under investigation include: Placebo (BIOLOGICAL), WN/DEN4Δ30 Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT02186626?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02186626's enrollment target sits among peer trials

28 1447th of 2000 higher than 538 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02186626, the US trial registry maintained by the National Library of Medicine. NCT02186626 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.