National Institute of Allergy and Infectious Diseases (NIAID)

2,006 total trials 155 currently recruiting 1642 completed

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Trial Pipeline

2,006 total, page 11 of 41

COMPLETED Phase 1

Safety, Tolerability, and Pharmacokinetics of SAB-301 in Healthy Adults

NCT02788188

COMPLETED Phase 1

Vedolizumab (Anti-alpha4beta7) in Subjects With HIV Infection Undergoing Analytical Treatment Interruption

NCT02788175

COMPLETED Phase 1

Magnesium Supplementation in People With XMEN Syndrome

NCT02496676

COMPLETED Phase 2

Evaluating the Safety and Tolerability of Ruxolitinib in Antiretroviral-Treated HIV-Infected Adults

NCT02475655

COMPLETED Phase 1

Cefixime / Azithromycin pK Study

NCT02708992

TERMINATED Phase 2

Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis

NCT02603146

COMPLETED Phase 4

Integrase and Maraviroc Intensification in Neurocognitive Dysfunction (InMIND)

NCT02519777

COMPLETED Phase 2

Safety and Efficacy of 5% Monolaurin Vaginal Gel Administered Intravaginally for the Treatment of Bacterial Vaginosis

NCT02709005

COMPLETED Phase 2

Evaluating the Safety and Efficacy of the VRC01 Antibody in Reducing Acquisition of HIV-1 Infection Among Men and Transgender Persons Who Have Sex With Men

NCT02716675

COMPLETED Phase 1

Evaluating the Safety, Tolerability, and Immunogenicity of a Prime-Boost Regimen of HIV-1 Nef/Tat/Vif, Env pDNA Vaccine Delivered Intramuscularly With Electroporation and HIV-1 rVSV envC Vaccine in Healthy, HIV-Uninfected Adults

NCT02654080

COMPLETED Phase 1

Evaluating the Safety and Immunogenicity of a Tetravalent Dengue Vaccine (TetraVax-DV) TV005 in Flavivirus-Naive Adults 50 to 70 Years of Age

NCT02879266

COMPLETED Phase 1

Cockroach Nasal Allergen Challenge Pilot

NCT02710136

COMPLETED

Sputum Pharmacokinetics of TB Drugs and Bacterial Drug Resistance

NCT02534727

COMPLETED Phase 2

H7N9 Boost in Healthy Adults

NCT02586792

COMPLETED Phase 1

CC-11050 in Human Immunodeficiency Virus-1-Infected Adults With Suppressed Plasma Viremia on Antiretroviral Therapy (APHRODITE)

NCT02652546

TERMINATED Phase 4

Efficacy Study of Fluconazole to Treat Coccidioidomycosis Pneumonia (Valley Fever)

NCT02663674

TERMINATED Phase 4

Analysis of Bone Marrow and Blood B Cell Immune Responses to Influenza Vaccination

NCT02485639

COMPLETED

CLAD Phenotype Specific Risk Factors and Mechanisms

NCT02631720

COMPLETED Phase 2

Evaluation of Donor Specific Immune Senescence and Exhaustion as Biomarkers of Tolerance Post Liver Transplantation

NCT02533180

TERMINATED Phase 2

Cardiometabolic Effects of Eplerenone in HIV Infection

NCT02629094

COMPLETED Phase 1

Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB080-00-AB (VRC01LS), With Broad HIV-1 Neutralizing Activity, Administered Intravenously or Subcutaneously to Healthy Adults

NCT02599896

COMPLETED Phase 1

Safety and PK of MBX-400 (Cyclopropavir) in Normal Volunteers

NCT02454699

COMPLETED Phase 2

Effects of Inhibiting Early Inflammation in Kidney Transplant Patients

NCT02495077

COMPLETED Phase 3

Comparing the Efficacy and Safety of High-Titer Versus Low-Titer Anti-Influenza Immune Plasma for the Treatment of Severe Influenza A

NCT02572817

COMPLETED Phase 1

Influenza A H3N2 Human Challenge Study in Healthy Adult Volunteers

NCT02594189

COMPLETED Phase 1

Optimal Human Dose for GII.2 Norovirus (Snow Mountain) Challenge Studies

NCT02473224

COMPLETED Phase 1

Safety, Tolerability, and Immunogenicity of the Vaccine Candidates ID93 + AP10-602 and ID93 + GLA-SE Administered Intramuscularly in Healthy Adult Subjects

NCT02508376

COMPLETED Phase 1

Study of Safety, Tolerability, and Efficacy of Ustekinumab for Symptomatic Gastrointestinal Inflammation Associated With Common Variable Immunodeficiency

NCT02199496

COMPLETED

Mechanisms Underlying Asthma Exacerbations Prevented and Persistent With Immune-Based Therapy

NCT02502890

COMPLETED Phase 1

Safety and Immunogenicity of the RSV D46cpΔM2-2 Vaccine in RSV-Seropositive Children and RSV-Seronegative Infants and Children

NCT02601612

COMPLETED Phase 1

Subcutaneous Immunotherapy for Mouse in Adults

NCT02532179

TERMINATED Phase 2

Emtricitabine/Tenofovir Alafenamide as Salvage ART

NCT02556333

TERMINATED Phase 2

Evaluating the Safety and Effectiveness of Interferon-Free Treatment of Hepatitis C Virus Infection in HIV-Coinfected Adults on Antiretroviral Therapy

NCT02194998

COMPLETED Phase 1

Evaluating the Safety and Protective Efficacy of a Single Dose of a Trivalent Live Attenuated Dengue Vaccine to Protect Against Infection With DENV-2

NCT02433652

TERMINATED Phase 1

Autologous Polyclonal Tregs for Lupus

NCT02428309

COMPLETED Phase 1

Evaluating the Safety, Tolerability, and Effect of a Human Monoclonal Antibody (VRC01) on Markers of HIV Persistence in HIV-Infected Adults Receiving Antiretroviral Therapy (ART)

NCT02411539

COMPLETED Phase 1

Evaluating the Safety of and Immune Response to a Human Parainfluenza Virus Type 3 Ebola Virus Vaccine (HPIV3-EbovZ GP) in Healthy Adults

NCT02564575

COMPLETED Phase 1

Evaluating the Safety, Pharmacokinetics, and Antiviral Activity of a Human Monoclonal Antibody (VRC01) in HIV-Infected Adults Undergoing a Brief Treatment Interruption

NCT02463227

COMPLETED Phase 1

Evaluating the Safety and Immunogenicity of PENNVAX®-GP DNA Vaccine and IL-12 Plasmid, Delivered Via Intradermal or Intramuscular Electroporation in Healthy, HIV-Uninfected Adults

NCT02431767

COMPLETED NA

Xenodiagnosis After Antibiotic Treatment for Lyme Disease

NCT02446626

COMPLETED Phase 1

Respiratory Syncytial Virus Human Challenge in Healthy Adult Volunteers

NCT02484417

COMPLETED Phase 1

Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B...

NCT02511054

COMPLETED Phase 1

VRC-HIVMAB060-00-AB (VRC01) in People With Chronic HIV Infection Undergoing Analytical Treatment Interruption

NCT02471326

COMPLETED Phase 2

Rituximab and Belimumab for Lupus Nephritis

NCT02260934

COMPLETED Phase 1

Evaluating the Safety and Pharmacokinetics of VRC01, VRC01LS, and VRC07-523LS, Potent Anti-HIV Neutralizing Monoclonal Antibodies, in HIV-1-Exposed Infants

NCT02256631

TERMINATED Phase 1

Immunologic Effects of Supplemental Monosaccharide and Nucleoside Derivatives in Patients With Inherited Disorders of Glycosylation

NCT02511041

COMPLETED

NIAID Clinical Center Genomics Opportunity Protocol

NCT02417766

COMPLETED Phase 1

Pharmacokinetics of Two Intravaginal Rings (IVRs) Containing Different Dose Strengths of Vicriviroc (MK-4176) and MK-2048

NCT02419456

COMPLETED Phase 1

A Phase I Study Priming With an Inactivated A/H7N9 Influenza Virus Vaccine With or Without MF59 Adjuvant Followed by Live Attenuated A/H7N9 Influenza Virus Vaccine

NCT02251288

COMPLETED Phase 1

Genitourinary and Pharyngeal Pharmacokinetics of Solithromycin

NCT02348424

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What the Pipeline for National Institute of Allergy and Infectious Diseases (NIAID) Shows

According to the ClinicalTrials.gov registry, National Institute of Allergy and Infectious Diseases (NIAID) is linked to 2,006 US clinical trials across every stage of research activity. Of those, 155 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 1,642 are already marked complete, representing roughly 82% of the total.

The phase mix for National Institute of Allergy and Infectious Diseases (NIAID) reports 177 late-stage studies (Phase 3 and Phase 4 combined) and 1,291 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Allergy and Infectious Diseases (NIAID) is HIV Infections with 195 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.