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NCT02654080 · ClinicalTrials.gov registry record · Phase 1

Evaluating the Safety, Tolerability, and Immunogenicity of a Prime-Boost Regimen of HIV-1 Nef/Tat/Vif, Env pDNA Vaccine Delivered Intramuscularly With Electroporation and HIV-1 rVSV envC Vaccine in Healthy, HIV-Uninfected Adults

A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
14
Enrollment target

NCT02654080 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 14 participants.

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The verdict

NCT02654080, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
14 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the safety and tolerability of an HIV-1 nef/tat/vif, env pDNA vaccine delivered with electroporation (EP), followed by a recombinant vesicular stomatitis virus (rVSV) HIV envC vaccine boost, in healthy, HIV-uninfected adults.

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL HIV-1 nef/tat/vif, env pDNA vaccine
  • BIOLOGICAL rVSV HIV envC vaccine

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2016-03
Est. Completion 2019-07-01
Phase Phase 1

What the Registry Record Tells You About NCT02654080

The ClinicalTrials.gov registry entry for NCT02654080 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT02654080 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02654080 about?

NCT02654080 is a clinical study titled "Evaluating the Safety, Tolerability, and Immunogenicity of a Prime-Boost Regimen of HIV-1 Nef/Tat/Vif, Env pDNA Vaccine Delivered Intramuscularly With Electroporation and HIV-1 rVSV envC Vaccine in Healthy, HIV-Uninfected Adults". The purpose of this study is to evaluate the safety and tolerability of an HIV-1 nef/tat/vif, env pDNA vaccine delivered with electroporation (EP), followed by a recombinant vesicular stomatitis virus (rVSV) HIV envC vaccine boost, in healthy, HIV-uninfected adults.

What is the current status of trial NCT02654080?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2016-03. Estimated completion is 2019-07-01.

What interventions are being tested in trial NCT02654080?

The interventions under investigation include: Placebo (BIOLOGICAL), HIV-1 nef/tat/vif, env pDNA vaccine (BIOLOGICAL), rVSV HIV envC vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT02654080?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.