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NCT02433652 · ClinicalTrials.gov registry record · Phase 1

Evaluating the Safety and Protective Efficacy of a Single Dose of a Trivalent Live Attenuated Dengue Vaccine to Protect Against Infection With DENV-2

A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
24
Enrollment target

NCT02433652 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 24 participants.

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The verdict

NCT02433652, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
24 participants
Enrollment target

Study Summary

Infection with dengue viruses is the leading cause of hospitalization and death in children in many tropical Asian countries, and the development of a dengue vaccine is a top health priority. This study will evaluate the ability of a single dose of a trivalent dengue vaccine to protect against infection with an attenuated candidate DENV-2 vaccine, administered 6 months after the trivalent dengue vaccine.

Interventions

  • BIOLOGICAL Placebo
  • BIOLOGICAL Recombinant live attenuated trivalent dengue vaccine
  • BIOLOGICAL rDEN2Δ30-7169 vaccine

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2015-09
Phase Phase 1

What the Registry Record Tells You About NCT02433652

The ClinicalTrials.gov registry entry for NCT02433652 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT02433652 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02433652 about?

NCT02433652 is a clinical study titled "Evaluating the Safety and Protective Efficacy of a Single Dose of a Trivalent Live Attenuated Dengue Vaccine to Protect Against Infection With DENV-2". Infection with dengue viruses is the leading cause of hospitalization and death in children in many tropical Asian countries, and the development of a dengue vaccine is a top health priority. This study will evaluate the ability of a single dose of a trivalent dengue vaccine to protect against infec...

What is the current status of trial NCT02433652?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2015-09.

What interventions are being tested in trial NCT02433652?

The interventions under investigation include: Placebo (BIOLOGICAL), Recombinant live attenuated trivalent dengue vaccine (BIOLOGICAL), rDEN2Δ30-7169 vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT02433652?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.