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NCT02419456 · ClinicalTrials.gov registry record · Phase 1

Pharmacokinetics of Two Intravaginal Rings (IVRs) Containing Different Dose Strengths of Vicriviroc (MK-4176) and MK-2048

A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
19
Enrollment target

NCT02419456 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 19 participants.

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The verdict

NCT02419456, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
19 participants
Enrollment target

Study Summary

Intravaginal rings (IVRs) may offer an ideal way to deliver antiretroviral (ARV) drugs to prevent HIV infection. This study will evaluate the pharmacokinetics and safety of two IVRs containing different doses of a combination of two HIV ARV drugs, vicriviroc (VCV) (MK-4176) and MK-2048, in healthy, HIV-uninfected women.

Interventions

  • DRUG MK-2048A IVR (Low Dose)
  • DRUG MK-2048A IVR (Original Dose)

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2015-06
Est. Completion 2016-03
Phase Phase 1

What the Registry Record Tells You About NCT02419456

The ClinicalTrials.gov registry entry for NCT02419456 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which MK-2048A IVR (Low Dose) is the first listed.

NCT02419456 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02419456 about?

NCT02419456 is a clinical study titled "Pharmacokinetics of Two Intravaginal Rings (IVRs) Containing Different Dose Strengths of Vicriviroc (MK-4176) and MK-2048". Intravaginal rings (IVRs) may offer an ideal way to deliver antiretroviral (ARV) drugs to prevent HIV infection. This study will evaluate the pharmacokinetics and safety of two IVRs containing different doses of a combination of two HIV ARV drugs, vicriviroc (VCV) (MK-4176) and MK-2048, in healthy, ...

What is the current status of trial NCT02419456?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2015-06. Estimated completion is 2016-03.

What interventions are being tested in trial NCT02419456?

The interventions under investigation include: MK-2048A IVR (Low Dose) (DRUG), MK-2048A IVR (Original Dose) (DRUG).

Who is sponsoring clinical trial NCT02419456?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.