Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00341549 · ClinicalTrials.gov registry record
Family Myopia Study
A clinical trial, sponsored by National Human Genome Research Institute (NHGRI).
- Completed
- Registry status
- 7,477
- Enrollment target
NCT00341549: Completed study, sponsored by National Human Genome Research Institute (NHGRI).
NCT00341549 is a clinical trial that has completed, run by National Human Genome Research Institute (NHGRI). The registered enrollment target is 7,477 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00341549 has completed, sponsored by National Human Genome Research Institute (NHGRI).
- COMPLETED
- Registry status
- 7,477 participants
- Enrollment target
Study Summary
This study will try to identify the gene or genes responsible for myopia (nearsightedness) and to examine the relationship between myopia and near work. Myopia is the most common eye disorder in the world, affecting one in four Americans. Several studies indicate that myopia is inherited. The condition tends to cluster in families, so that studying families with this condition may facilitate finding the exact cause. Caucasian Americans and African Americans with myopia who are in general good health may be eligible for this study. People with a family history of myopia through several generations along one parent s side only, and in which more than one sibling has myopia are preferred. People who have severe diseases that involve myopia, such as Stickler s or Marfan syndromes, retinitis pigmentosa or diabetic retinopathy may not participate. Participants will undergo the following tests and procedures: * Eye examination, including refraction * Blood draw for genetic studies and possibly establishment of cell lines (collection of cells grown in the laboratory from an original tissue specimen) for future research * Myopia Family Study Questionnaire and personal medical information questionnaire to provide information about other medical conditions that may influence the development of myopia; the vision status of their spouse and children, parents and siblings, and spouse s parents and siblings * Risk Factor Questionnaire (for Jewish Orthodox community only) to assess the amount of near work activity done in childhood
Primary Outcome
The overall objective for this project is to query the entire human genome to identify the genes responsible for myopia and for variation in ocular refraction.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7,477 participants |
| Start Date | 2002-04-29 |
| Est. Completion | 2020-03-12 |
What the finished NCT00341549 record still lists
NCT00341549 is an observational study that tracks outcomes without assigning an intervention. Its 7,477 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 0 interventions.
NCT00341549 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00341549 about?
NCT00341549 is a clinical study titled "Family Myopia Study". This study will try to identify the gene or genes responsible for myopia (nearsightedness) and to examine the relationship between myopia and near work. Myopia is the most common eye disorder in the world, affecting one in four Americans. Several studies indicate that myopia is inherited. The condit...
What is the current status of trial NCT00341549?
This trial is currently completed. The enrollment target is 7,477 participants. The study started on 2002-04-29. Estimated completion is 2020-03-12.
Who is sponsoring clinical trial NCT00341549?
This trial is sponsored by National Human Genome Research Institute (NHGRI), which has 185 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00439049 · 7,500 participants
Substance Abuse Pre-Treatment Screening Study
- NCT04809740 · 7,500 participants · NA
Evaluating the Implementation and Impact of Navigator-delivered ePRO System
- NCT05199701 · 7,500 participants · NA
Prospective Case Collection Study for New Mammography Technologies
- NCT06112418 · 7,500 participants · NA
A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI