Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 52 of 57

COMPLETED NA

Improved Time in Therapeutic Range With Patient Self-Testing of Their INR Compared to Usual Care

NCT00703963
TERMINATED Phase 4

A Trial on Laparoscopic Hysterectomy Versus Robotic Hysterectomy

NCT00895284
TERMINATED NA

Endothelial Function and Autonomic Regulation After Short-term Smoking Cessation: Varenicline Versus Placebo

NCT00673595
COMPLETED NA

X-3 Polyethylene Survival Outcomes Study

NCT00493792
COMPLETED Phase 1

Allogeneic Stem Cell Transplantation for Patients With Severe Aplastic Anemia

NCT00578266
COMPLETED Phase 2

Efficacy of Betaine for Reduction of Urine Oxalate in Patients With Type 1 Primary Hyperoxaluria

NCT00283387
COMPLETED

Registration and Fusion of Real-Time Ultrasound With CT for Lesion Localization and Characterization

NCT00586235
COMPLETED Phase 2

Trial of Mesalamine for the Treatment of Active Microscopic Colitis

NCT00952952
TERMINATED

Cathartic-Free DECT Colonography for Detection of Colonic Polyps

NCT00587028
COMPLETED Phase 1

Gold Sodium Thiomalate in Treating Patients With Advanced Non-Small Cell Lung Cancer

NCT00575393
COMPLETED Phase 1

Vatalanib and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors

NCT00390000
COMPLETED NA

Oral Paricalcitol in Kidney Transplant Recipients

NCT00587158
COMPLETED Phase 2

Octreotide in Severe Polycystic Liver Disease

NCT00426153
COMPLETED Phase 3

Nicotine Lozenges for Treatment of Smokeless Tobacco Addiction

NCT00392379
COMPLETED Phase 1

Omega 3 Fatty Acid Trial

NCT00586222
COMPLETED Early Phase 1

Rituximab and Prednisone as First-Line Therapy in Treating Patients With Immune Thrombocytopenic Purpura

NCT00486421
TERMINATED Phase 2

Phase 2 Study of PEG-Intron in Hereditary Hemorrhagic Telangiectasia

NCT00588146
TERMINATED NA

Prophylactic Pulmonary Vein Isolation Study

NCT00587899
COMPLETED NA

Effects of Androgen Administration on Inflammation in Normal Women

NCT01753037
COMPLETED Phase 2

Cyclophosphamide, Bortezomib, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma

NCT00609167
COMPLETED Phase 1

Vaccine Therapy With or Without Cyclophosphamide in Treating Patients With Recurrent or Refractory Multiple Myeloma

NCT00450814
COMPLETED

Tumor Response to Pemetrexed Disodium in Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Enrolled in Clinical Trial MCCRC-RC0524

NCT00898820
COMPLETED Phase 1

Tobacco Cessation Treatment for Pregnant Alaska Natives

NCT00379444
COMPLETED Phase 2

Pemetrexed Disodium and Gemcitabine in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer

NCT00407550
TERMINATED Phase 1

Secretin (ChiRhoStim) Pancreas Perfusion for Pancreatic Adenocarcinoma

NCT00587132
COMPLETED Phase 1

Viral Therapy in Treating Patients With Recurrent Glioblastoma Multiforme

NCT00390299
COMPLETED Phase 1

Study of Radioimmunoguided Intensity Modulated Radiotherapy (IMRT) for Prostate Cancer

NCT00956228
COMPLETED NA

Range of Motion and Patients With Distal Radius Fractures

NCT00816998
COMPLETED Phase 2

Functional Dyspepsia Treatment Trial

NCT00248651
COMPLETED NA

Molecular Breast Imaging in Patients With a History of Bloody Nipple Discharge

NCT00566280
COMPLETED Phase 1

Open-Label Adalimumab for Ulcerative Colitis Patients

NCT00421642
COMPLETED Early Phase 1

Rituximab in the Treatment of Idiopathic Membranous Nephropathy

NCT00405340
COMPLETED

Scalar Localization Cochlear Electrode Array Using 64 Slice CT

NCT00587262
COMPLETED Phase 4

Cardiac Limitations in Chronic Obstructive Pulmonary Disease: Benefits of Bronchodilation

NCT00578968
TERMINATED NA

Epidural Clonidine for Lumbosacral Radiculopathy

NCT00588354
TERMINATED Phase 1

Cardiopulmonary Bypass-Induced Lymphocytopenia and the Potential Effects of Protease Inhibitor

NCT00385450
COMPLETED Phase 2

Nesiritide Therapy to Preserve Function of the Left Ventricle After Myocardial Infarction

NCT00573144
COMPLETED Phase 2

FolateScan in Autoimmune Disease

NCT00588393
COMPLETED NA

Ablation vs Drug Therapy for Atrial Fibrillation - Pilot Trial

NCT00578617
COMPLETED Phase 4

Incretins in Impaired Fasting Glucose

NCT00364377
COMPLETED NA

Lung Rehabilitation in Treating Patients With Chronic Obstructive Pulmonary Disease Who Are Undergoing Surgery for Lung Cancer

NCT00363428
COMPLETED Phase 4

Pilot Study: Preoperative Nicotine Lozenges

NCT00586482
COMPLETED NA

Low Dose Ketamine as an Adjunct to Fentanyl in Outpatient Tonsillectomy

NCT00587665
TERMINATED Phase 2

Azacitidine in Treating Patients With Myelofibrosis

NCT00381693
COMPLETED

Confocal Microscopy in Barrett's Esophagus

NCT00587184
COMPLETED Phase 2

Detection and Classification of Colon Polyps

NCT00825292
COMPLETED Phase 2

Lenalidomide, Cyclophosphamide, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma

NCT00478218
COMPLETED Phase 4

Weight Loss in Response to Sibutramine (MERIDIA) is Influenced by the Inherited Genes

NCT00433641
COMPLETED Phase 3

Is Plasma Transfusion Beneficial Prior to Low-Risk Procedures in Hospitalized Patients With Blood Clotting Abnormalities?

NCT00953901
COMPLETED NA

Diabetes Medication Choice

NCT00388050
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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

Therapeutic Areas

Healthy 36
Malignant Solid Neoplasm 35
Obesity 31
Breast Cancer 25
Breast Carcinoma 21
Hematopoietic and Lymphatic System Neoplasm 20
Hematopoietic and Lymphoid System Neoplasm 12
Heart Failure 11
Cancer 11
Prostate Carcinoma 9

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Related

Compare saved trials side-by-side

Read our methodology - how this data is sourced, computed, and verified.
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.