Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 51 of 57

COMPLETED Phase 4

The Use of Statins Following a Left Atrial Catheter Ablation Procedure to Prevent Atrial Fibrillation

NCT00579098

COMPLETED NA

Stroke DOC Arizona TIME - Stroke Team Remote Evaluation Using a Digital Observation Camera

NCT00623350

TERMINATED Phase 3

AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study

NCT00589303

TERMINATED Phase 2

Sorafenib and Letrozole, Anastrozole, or Exemestane in Treating Postmenopausal Women With Estrogen Receptor-Positive and/or Progesterone Receptor-Positive Metastatic Breast Cancer

NCT00573755

COMPLETED NA

GLP1R Polymorphisms and Response to GLP1

NCT00588380

COMPLETED NA

Amiodarone for the Prevention of Reperfusion Ventricular Fibrillation

NCT00587483

COMPLETED Phase 2

CC-4047 and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma or Amyloidosis

NCT00558896

COMPLETED

Mechanisms in Heart Failure With Normal EF

NCT00587808

TERMINATED NA

Transit Time and Bacterial Overgrowth Using SmartPill Capsule

NCT00577772

TERMINATED

Study of Circulating Cancer Cells in Patients With Metastatic Breast, Ovarian, Colon, or Pancreatic Cancer

NCT00898781

COMPLETED NA

Metabolic Syndrome Diagnosis and Education Trial

NCT00943254

COMPLETED

Endoscopic Mucosal Resection (EMR) in Barrett's Esophagus

NCT00586872

COMPLETED NA

Remote Myocardial Ischemic Preconditioning in Humans

NCT00588042

COMPLETED

Novel Method of Surveillance in Barrett's Esophagus

NCT00955019

COMPLETED

Dynamic MRI Evaluation Post Operative Stapled Trans Anal Rectal Resection (STARR) Procedure

NCT00655382

COMPLETED

Aqueous Outflow Facility Changes With Posture

NCT00571012

COMPLETED Phase 2

Gabapentin for Smoking Cessation

NCT00578552

COMPLETED Phase 4

Lubiprostone, Colonic Motility and Sensation

NCT00953043

COMPLETED NA

Enhancing Smoker Utilization of the Minnesota Quitline Through Support Persons

NCT01311830

COMPLETED Phase 1

Sorafenib and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

NCT00474929

COMPLETED Phase 1

Acid Reflux and Stromal Fibroblasts in Barrett's Esophagus

NCT00573911

COMPLETED NA

Osteoporosis Choice Decision Aid for Use of Bisphosphonates in Postmenopausal Women

NCT00578981

COMPLETED Phase 1

Trial of Montelukast in Eosinophilic Esophagitis

NCT00511316

COMPLETED NA

Acupuncture and Post-Operative Ileus

NCT00655317

COMPLETED Phase 2

Behavioral Trial Studying Programmed Training to Improve Advocacy Skills for Individuals With Traumatic Brain Injury

NCT01002677

TERMINATED Phase 2

Methadone Versus Morphine for Cancer-Related Pain

NCT00573937

COMPLETED Phase 1

Analysis of the Mechanisms of Protective Humoral Immunity in Response to the Pneumococcal Vaccine

NCT00589394

COMPLETED NA

Strategies for Aggressive Central Afterload Reduction in Patients With Heart Failure

NCT00588692

COMPLETED NA

Deep Brain Stimulation in Patients With Parkinson's Disease

NCT00586079

COMPLETED NA

Space and Interaction Trial: Room Design and Patient-physician Interaction

NCT00806559

COMPLETED Phase 3

Chantix & Bupropion for Smoking Cessation

NCT00587769

COMPLETED NA

Quitline Use in Surgical Patients

NCT00656500

COMPLETED NA

Paravertebral Blocks: Pilot Study to Compare Nerve Stimulation vs. Anatomic Landmarks in Inguinal Hernia Repair

NCT00587704

TERMINATED Phase 4

Aprepitant for Prevention of Postoperative Nausea and Vomiting in Elective Hysterectomy

NCT00888329

TERMINATED Phase 3

Aspirin for Treatment of Multiple Sclerosis-Related Fatigue

NCT00467584

COMPLETED NA

An Evaluation of Safety and Feasibility Using Repetitive Transcranial Magnetic Stimulation (rTMS) in Adolescents With Depression

NCT00587639

COMPLETED

Sensitivity to Change of the Lower Extremity Functional Scale in Patients With Stroke

NCT01536990

COMPLETED Phase 2

Epoetin Alfa or Darbepoetin Alfa in Treating Patients With Anemia Caused by Chemotherapy

NCT00416624

COMPLETED NA

Autosomal Dominant Polycystic Kidney Disease (ADPKD) Pain Study

NCT00571909

COMPLETED

Role of CXCR2 Ligands/CXCR2 Biological Axis in Pancreatic Cancer

NCT00851955

COMPLETED Phase 1

Stereotactic Radiation Therapy in Treating Patients With Liver Metastases

NCT00567970

COMPLETED Phase 1

Concentration of Itraconazole Solution in Nasal Secretions

NCT00588016

COMPLETED

Heart Failure and a Preserved Ejection Fraction

NCT00586833

COMPLETED Phase 2

Doxorubicin and Cyclophosphamide Followed By Trastuzumab, Paclitaxel, and Lapatinib in Treating Patients With Early-Stage HER2-Positive Breast Cancer That Has Been Removed By Surgery

NCT00436566

COMPLETED NA

Differences in Epicardial Plaque and Microvascular Function in Women With an Acute Myocardial Infarction

NCT00587002

COMPLETED NA

Safety and Efficacy of Oral Midazolam for Perioperative Anxiety Relief of Patients Undergoing Mohs Micrographic Surgery

NCT00578214

COMPLETED NA

Minimally Invasive Surgical Approaches In Total Knee Arthroplasty

NCT01461356

COMPLETED NA

Three Different Programs of Paced Breathing in Treating Hot Flashes in Women

NCT00569166

COMPLETED Phase 1

Vaccine Therapy and GM-CSF With or Without Low-Dose Aldesleukin in Treating Patients With Stage II, Stage III, or Stage IV Melanoma

NCT00470015

COMPLETED Phase 2

Lapatinib and Topotecan in Treating Patients With Ovarian Epithelial Cancer or Primary Peritoneal Cancer That Did Not Respond to Cisplatin or Carboplatin

NCT00436644

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.