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NCT00385450 · ClinicalTrials.gov registry record · Phase 1
Cardiopulmonary Bypass-Induced Lymphocytopenia and the Potential Effects of Protease Inhibitor
A Phase 1 study, sponsored by Mayo Clinic.
- Terminated
- Registry status
- Phase 1
- Development phase
- 41
- Enrollment target
NCT00385450: Clinical Trial Phase 1 study, sponsored by Mayo Clinic.
NCT00385450 is a Phase 1 study that was terminated before completion, run by Mayo Clinic. The registered enrollment target is 41 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00385450, a Phase 1 study, was terminated before completion, sponsored by Mayo Clinic.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 41 participants
- Enrollment target
Study Summary
In previous studies, 90% of patients who underwent elective cardiopulmonary bypass procedure manifested CD4 counts of less than 500 cells/microliter in the immediate (day 1) post-operative period. This study will investigate whether or not Nelfinavir increases those CD4 counts in the post-operative period.
Interventions
- DRUG Nelfinavir/placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2006-10 |
| Est. Completion | 2008-10 |
| Phase | Phase 1 |
Why NCT00385450 stopped before completion
NCT00385450 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (32% lower).
The record links to 0 conditions, and to 1 intervention - of which Nelfinavir/placebo is the first listed.
NCT00385450 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00385450 about?
NCT00385450 is a clinical study titled "Cardiopulmonary Bypass-Induced Lymphocytopenia and the Potential Effects of Protease Inhibitor". In previous studies, 90% of patients who underwent elective cardiopulmonary bypass procedure manifested CD4 counts of less than 500 cells/microliter in the immediate (day 1) post-operative period. This study will investigate whether or not Nelfinavir increases those CD4 counts in the post-operative ...
What is the current status of trial NCT00385450?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 41 participants. The study started on 2006-10. Estimated completion is 2008-10.
What interventions are being tested in trial NCT00385450?
The interventions under investigation include: Nelfinavir/placebo (DRUG).
Who is sponsoring clinical trial NCT00385450?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00385450's enrollment target sits among peer trials
41 1125th of 2000 higher than 871 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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