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NCT00578266 · ClinicalTrials.gov registry record · Phase 1
Allogeneic Stem Cell Transplantation for Patients With Severe Aplastic Anemia
A Phase 1 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 8
- Enrollment target
NCT00578266: Completed Phase 1 study, sponsored by Mayo Clinic.
NCT00578266 is a Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 8 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00578266, a Phase 1 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 8 participants
- Enrollment target
Study Summary
For patients with severe aplastic anemia (SAA) who have failed to respond to immunosuppressive therapy and lack an HLA identical family member, our objectives are to make an initial assessment of the safety and efficacy of allogenic stem cell transplantation from either a matched unrelated donor or a mismatched reacted donor using the conditioning regimen of Cytoxan, reduced total body irradiation (TBI) and Campath IH. The principle measures of safety and efficacy will be : 1. Patient survival probability at 100 days, 1 year and 2 years. 2. Incidence of graft versus host disease (GVHD), as well as incidence of acute GVHD and chronic GVHD within 6 months and 2 years. 3. Engraftment at 6 months, 1 year and 2 years
Interventions
- DRUG Cyclophosphamide,Campath IH and TBI
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2007-02 |
| Est. Completion | 2016-08-16 |
| Phase | Phase 1 |
What the finished NCT00578266 record still lists
NCT00578266 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 1 intervention - of which Cyclophosphamide,Campath IH and TBI is the first listed.
NCT00578266 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00578266 about?
NCT00578266 is a clinical study titled "Allogeneic Stem Cell Transplantation for Patients With Severe Aplastic Anemia". For patients with severe aplastic anemia (SAA) who have failed to respond to immunosuppressive therapy and lack an HLA identical family member, our objectives are to make an initial assessment of the safety and efficacy of allogenic stem cell transplantation from either a matched unrelated donor or ...
What is the current status of trial NCT00578266?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2007-02. Estimated completion is 2016-08-16.
What interventions are being tested in trial NCT00578266?
The interventions under investigation include: Cyclophosphamide,Campath IH and TBI (DRUG).
Who is sponsoring clinical trial NCT00578266?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00578266's enrollment target sits among peer trials
8 1959th of 2000 higher than 29 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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