Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 53 of 57

TERMINATED Phase 1

Islet Transplantation for Type 1 Diabetes Mellitus

NCT00437398

COMPLETED Phase 4

Local Anesthesia for Prostate Biopsy

NCT00422708

COMPLETED NA

Skin Conduction Device and Patient Diary for Measuring Hot Flashes in Postmenopausal Women With Hot Flashes

NCT00427531

COMPLETED Phase 1

Human B-type Natriuretic Peptide (BNP) (Nesiritide) to Help Heart, Kidney, and Hormonal Functions in Persons With Lower Heart Pumping Function

NCT00405639

TERMINATED Phase 2

Paclitaxel and Carboplatin or Temozolomide in Treating Patients With Stage IV Melanoma

NCT00568451

COMPLETED NA

Skin Conduction Device for Measuring Hot Flashes in Postmenopausal Women With Hot Flashes

NCT00427622

COMPLETED

Markers of Bone Turnover in Saliva and How This Compares to Urine and Blood

NCT00323336

COMPLETED NA

Effect of Revival Soy on Fibromyalgia Pain

NCT00279942

COMPLETED Phase 1

Use of Pyridostigmine for Constipation in Diabetics

NCT00276406

COMPLETED

CT Pancreas Perfusion

NCT00588367

COMPLETED Phase 4

Preemptive Local Anesthesia in Vaginal Surgery

NCT00318292

COMPLETED NA

Zoledronate in Treating Osteopenia or Osteoporosis in Postmenopausal Women Receiving Letrozole for Stage I, Stage II, or Stage IIIA Primary Breast Cancer

NCT00436917

COMPLETED Phase 1

Evaluation of Atuna Racemosa Toxicity

NCT00318344

COMPLETED Phase 2

Bevacizumab in Treating Patients With Relapsed or Refractory Multiple Myeloma

NCT00482495

COMPLETED

High Resolution Phenotyping in Healthy Humans

NCT00943774

COMPLETED Early Phase 1

Vaccine Therapy and Resiquimod in Treating Patients With Stage II, Stage III, or Stage IV Melanoma That Has Been Completely Removed by Surgery

NCT00470379

COMPLETED

High Risk Screening Breast MR Using a Rapid Imaging Exam

NCT00588614

COMPLETED NA

Sulindac Capsules Compared With Sulindac Tablets in Healthy Volunteers

NCT00343629

COMPLETED Phase 1

Use of an Herbal Preparation to Prevent and Dissolve Kidney Stones

NCT00381849

COMPLETED NA

Exercise for Fibromyalgia

NCT01253395

TERMINATED NA

Orthopedic Study of the Aircast StabilAir Wrist Fracture Brace

NCT00587795

TERMINATED Phase 2

Thalidomide for the Treatment of Primary Sclerosing Cholangitis (PSC)

NCT00953615

COMPLETED NA

Vibro-Acoustography Imaging in Diagnosing Breast Masses in Women With a Breast Mass or Breast Cancer

NCT00627614

COMPLETED Phase 1

Botulin-A Toxin Instillations and Overactive Bladder

NCT00583219

COMPLETED Phase 1

Alefacept in Treating Patients With Relapsed or Refractory Cutaneous T-Cell Lymphoma or Peripheral T-Cell Non-Hodgkin's Lymphoma

NCT00438802

COMPLETED NA

Cardiac Sympathetic Activity in Patients With the Apical Ballooning Syndrome

NCT00586183

COMPLETED NA

Faculty Development to Improve Mini-CEX Ratings

NCT00667940

COMPLETED

A Pilot Study on Pacemaker Interference From Peripheral Nerve Stimulator for Regional Anesthesia

NCT00586248

COMPLETED

Compare Conventional Colonosocpy to Endoscopic AFI, NBI for Dysplasia Detection for Ulcerative Colitis & Cholangitis

NCT00587236

COMPLETED

Common Genetic Variation and Type 2 Diabetes

NCT00707616

COMPLETED

Capsaicin Cough Threshold in Chronic Cough Due to Postnasal Drip

NCT00588627

TERMINATED NA

Does Thiazolidinedione Therapy Improve Endothelial Function and Preserve Renal Function

NCT00586261

COMPLETED Phase 1

Use of Oral Probiotics to Reduce Urinary Oxalate Excretion

NCT00587041

COMPLETED Phase 2

A Placebo-Controlled Trial of St. John's Wort for Irritable Bowel Syndrome

NCT00587860

TERMINATED NA

Electroacupuncture in Treating Chronic Dry Mouth Caused By Radiation Therapy in Patients With Head and Neck Cancer

NCT00623129

COMPLETED NA

Evaluate and Compare the Rate of Para-Stomal Herniation After Permanent Stoma Formation

NCT00577603

COMPLETED Phase 3

Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer

NCT00661999

COMPLETED NA

Gastric Motor Function Measurement in Dyspepsia and Normal Subjects

NCT00296582

COMPLETED

A Simple Clinical Tool to Help Assess Patient Volume (Fluid) Status

NCT00599794

TERMINATED NA

Intraoperative Gamma Probe Localization of the Ureter

NCT00587548

COMPLETED Phase 1

Testosterone-Driven Growth-Hormone (GH) Secretion in Aging Men

NCT00309855

COMPLETED

The Influence of SISCOM on Intracranial Electrode Implantation in Epilepsy Surgical Candidates

NCT00587951

COMPLETED Phase 4

The Comparison of Three Different Immunosuppressant Regimens in Kidney Transplant Recipients.

NCT00275522

COMPLETED NA

Treatment Study of Soft Palatal Implants in Obstructive Sleep Apnea

NCT00263770

COMPLETED NA

The Impact of Lorazepam on Cognition in APOE e4 Carriers

NCT00586430

COMPLETED Phase 3

Fat Gain and Cardiovascular Disease Mechanisms

NCT00589498

COMPLETED Phase 1

Radiofrequency Therapy-Induced Endogenous Heat-Shock Proteins With or Without Radiofrequency Ablation or Cryotherapy in Treating Patients With Stage IV Melanoma

NCT00568763

COMPLETED Phase 1

Is Botox Effective in Relieving Pain From Knee Osteoarthritis?

NCT00279903

COMPLETED Phase 2

A Study to Evaluate the Effect of a Medicine on Gastric Functions in Healthy Volunteers.

NCT00308399

COMPLETED Phase 4

Diagnosis and Treatment of Acute Coronary Syndrome in the ED & the Impact of Rapid Bedside cTnl on Outcome.

NCT00276432

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.