Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 50 of 57

COMPLETED Phase 2

Pentostatin, Alemtuzumab, and Rituximab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

NCT00669318

TERMINATED NA

Study Evaluating Benefit of Using Fibrin Glue in Septorhinoplasty

NCT00713596

COMPLETED Phase 1

CD-NP in Subjects With Stable Chronic Heart Failure

NCT00620308

COMPLETED

Mycobacterium Avium Intracellulare Complex (MAC) Study

NCT00826423

COMPLETED

Acceleration and Relapse Prevention With Triiodothyronine (T3) as an Adjunct to Electroconvulsive Therapy (ECT)

NCT01299337

COMPLETED

Production of Free Fatty Acids From Blood Triglycerides

NCT00911482

COMPLETED Phase 1

A Pharmacokinetic Evaluation of Bioidentical Compounded Estrogen Cream and Natural Progesterone

NCT00864214

COMPLETED Phase 1

Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer

NCT00654160

COMPLETED NA

Evaluation of a Biofeedback-assisted Meditation Program as a Stress Management Tool for Hospital Nurses

NCT01011790

COMPLETED Phase 2

The Impact of Velcade(TM)on Antibody Secreting Cells in Sensitized Renal Allograft Candidates

NCT00722722

TERMINATED Phase 4

A Trial Comparing Yield of Confocal Endomicroscopy Guided Biopsies

NCT01030263

COMPLETED

Acamprosate: Genes Associated With Response

NCT00662571

COMPLETED Phase 2

The Role Of Gastroesophageal Reflux Disease (GERD) in Eosinophilic Esophagitis

NCT00728481

COMPLETED NA

Effects of Resistance and Endurance Training on Synthesis of Individual Muscle Proteins in Young and Older Adults

NCT01489930

COMPLETED NA

Workplace Intervention: Activity Monitoring as a Tool for Corporate Wellness and Weight Loss

NCT01461382

COMPLETED Phase 1

CC-4047 in Treating Patients With Myelofibrosis

NCT00669578

COMPLETED

Modulating Effects of Lisinopril on Sildenafil Activity in Pulmonary Arterial Hypertension(PAH)( MELISSA)

NCT01181284

TERMINATED Phase 2

Anti-thymocyte Globulin and Melphalan in Treating Patients With Relapsed Multiple Myeloma

NCT00635024

TERMINATED NA

Comparison of Cyanoacrylate Tissue Adhesive and Suture for Closure of Cardiac Device Pockets

NCT00674128

TERMINATED NA

Prolotherapy Versus Steroids for Thumb Carpo-metacarpal Joint Arthritis

NCT00685880

COMPLETED Phase 1

Monoclonal Antibody Therapy in Treating Patients With Stage IV Melanoma

NCT00658892

COMPLETED

Micro-RNA (miR) Expression in Upper Gastrointestinal Mucosal Tissue

NCT00909350

COMPLETED Phase 2

Varenicline For Smokers In Recovery From Alcohol Dependence

NCT01092702

COMPLETED

Alveoscopy, Endoscopic Confocal Microscopy and Lung Rejection, Parenchymal Lung Diseases in Vivo

NCT01033201

COMPLETED Phase 2

A Pilot Study Evaluating Nicotine Lozenges and Self Help

NCT00888459

COMPLETED NA

Measuring the Effect of Therapeutic Massage on Pain and Discomfort in Cardiac Cath Lab Staff

NCT01048164

COMPLETED Phase 4

Assessing the Role of "Statin" Therapy and Perioperative Inflammatory Response in Patients Undergoing Major Orthopedic Surgery

NCT00656292

TERMINATED Phase 3

Over Active Bladder Instillation Study - Botox

NCT00667095

COMPLETED

Confocal Probe-based Endoscopic Imaging, Colorectal Cancer, Gastrointestinal (GI) Pathologies

NCT00874263

COMPLETED NA

Meditation to Reduce Stress and Improve Quality of Life

NCT01047917

COMPLETED

International Registry for Intraductal Papillary Mucinous Neoplasma

NCT00828048

COMPLETED Phase 1

Human Brain Natriuretic Peptide (BNP) (or Nesiritide) to Help Heart, Kidney and Humoral Function.

NCT00405548

COMPLETED

Predictive Genetic Risk Assessment Trial

NCT00782366

TERMINATED Phase 2

Low-Dose Decitabine in Treating Patients With Symptomatic Myelofibrosis

NCT00630994

COMPLETED

Effects of Cranberry Juice on Risk Factors for Cardiovascular Disease

NCT00631306

COMPLETED Phase 2

Rituximab, Pentostatin, Cyclophosphamide, and Lenalidomide in Treating Patients With Previously Untreated B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

NCT00602836

COMPLETED NA

The Effect of Grape Seed Extract on Estrogen Levels of Postmenopausal Women

NCT00566553

COMPLETED

Effects of EGCG-Enhanced Extra Virgin Olive Oil on Endothelial Function

NCT00865787

COMPLETED Phase 2

Rituximab, Alemtuzumab, and GM-CSF As First-Line Therapy in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia

NCT00562328

COMPLETED

Hormonal Effects on Tc-99m Sestamibi Uptake in the Breast

NCT00943527

COMPLETED

Proton Pump Inhibitor (PPI) Therapy for Newly Diagnosed Esophagitis

NCT00586963

COMPLETED

Minimally Invasive Detection of Lymphatic Micrometastases in Pancreatic Cancer

NCT00826982

COMPLETED NA

New Technique as an Additional Diagnostic Tool for Women Undergoing Neoadjuvant Therapy for Breast Cancer

NCT00566085

COMPLETED Phase 2

Testing Methylphenidate for Smoking Abstinence

NCT00549640

COMPLETED Phase 2

Tobacco Use Intervention Among Radiation Oncology Patients

NCT00587353

COMPLETED Phase 3

Two Different Methods of Collecting Stem Cells For an Autologous Stem Cell Transplant in Treating Patients With Diffuse Large Cell Lymphoma

NCT00566228

COMPLETED Phase 2

Lenalidomide, Cyclophosphamide, and Dexamethasone in Treating Patients With Primary Systemic Amyloidosis

NCT00564889

COMPLETED Phase 2

Cyrotherapy vs. APC in GAVE

NCT00587405

COMPLETED Phase 1

Audio Recording for Improved Surgical Outcome (ARISO)

NCT00569933

COMPLETED

Endoscopic Tri-Modal Imaging in Patients With Barrett's Esophagus

NCT00586989

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.