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NCT00669318 · ClinicalTrials.gov registry record · Phase 2
Pentostatin, Alemtuzumab, and Rituximab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
A Phase 2 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 2
- Development phase
- 41
- Enrollment target
NCT00669318: Completed Phase 2 study, sponsored by Mayo Clinic.
NCT00669318 is a Phase 2 study that has completed, run by Mayo Clinic. The registered enrollment target is 41 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00669318, a Phase 2 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 41 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy, such as pentostatin, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as alemtuzumab and rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Giving pentostatin together with alemtuzumab and rituximab may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving pentostatin together with alemtuzumab and rituximab works in treating patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.
Interventions
- BIOLOGICAL rituximab
- BIOLOGICAL alemtuzumab
- DRUG pentostatin
- DRUG sargramostim
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2008-07 |
| Est. Completion | 2014-05 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00669318
The ClinicalTrials.gov registry entry for NCT00669318 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which rituximab is the first listed.
NCT00669318 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00669318 about?
NCT00669318 is a clinical study titled "Pentostatin, Alemtuzumab, and Rituximab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma". RATIONALE: Drugs used in chemotherapy, such as pentostatin, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as alemtuzumab and rituximab, can block cancer growth in different ways. Some block the ab...
What is the current status of trial NCT00669318?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 41 participants. The study started on 2008-07. Estimated completion is 2014-05.
What interventions are being tested in trial NCT00669318?
The interventions under investigation include: rituximab (BIOLOGICAL), alemtuzumab (BIOLOGICAL), pentostatin (DRUG), sargramostim (DRUG).
Who is sponsoring clinical trial NCT00669318?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
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