Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 49 of 57

TERMINATED NA

Chronic Post Breast Surgery Pain

NCT00847067

TERMINATED Phase 1

Study of Low Dose Nesiritide With or Without Sildenafil in Congestive Heart Failure Patients With Renal Dysfunction

NCT00818701

TERMINATED NA

Polycystic Liver Disease in Kidney Transplant

NCT00934791

COMPLETED

Molecular Breast Imaging (MBI) in Patients With Suspected Ductal Carcinoma in Situ (DCIS)

NCT00890994

COMPLETED Phase 1

Dose-Finding Pilot Study of ACTH in Patients With Idiopathic Membranous Nephropathy

NCT00805753

COMPLETED

Exploratory Study of Potential Pulmonary Aspiration Markers From Bronchoalveolar Lavage Fluid

NCT00915941

COMPLETED NA

Evaluation of an Antidepressant Pharmacogenomic Algorithm in an Outpatient Clinical Setting

NCT01610063

COMPLETED Phase 2

Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction

NCT01018394

COMPLETED Phase 4

Improving Venous Thromboembolism Prophylaxis

NCT01304108

COMPLETED

Quality of Life in Patients Undergoing Radiation Therapy for Primary Lung Cancer, Head and Neck Cancer, or Gastrointestinal Cancer

NCT00836992

COMPLETED Phase 2

Portion Control Treatment for Obesity

NCT01451554

COMPLETED Phase 2

Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit in Diarrhea-predominant Irritable Bowel Syndrome (D-IBS)?

NCT00911612

COMPLETED

Barrett's Esophagus in Olmsted County

NCT00943280

TERMINATED Phase 2

Vaccine Therapy in Treating Patients With Non-Metastatic Prostate Cancer

NCT00814892

COMPLETED Phase 2

Lenalidomide With or Without Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma

NCT00772915

COMPLETED

Timing and Intensity of the Exposures and Attributable Burden of Acute Lung Injury

NCT00980915

COMPLETED NA

Sleep Deprivation and Energy Balance

NCT01334788

COMPLETED NA

Chronotherapy Versus Conventional BP Control to Correct Abnormal Circadian BP Pattern in Kidney Transplant Recipients

NCT01093703

TERMINATED Phase 1

Benefits of the Use of Botox in the Treatment of Empty Nose Syndrome Syndrome

NCT00732680

TERMINATED Phase 1

Gene Therapy and Radioactive Iodine in Treating Patients With Locally Recurrent Prostate Cancer That Did Not Respond to External-Beam Radiation Therapy

NCT00788307

COMPLETED

Cholangioscopy Using Narrow Band Imaging (NBI) in Patients With Primary Sclerosing Cholangitis (PSC) Undergoing Endoscopic Retrograde Cholangiopancreatogram (ERCP)

NCT00951327

COMPLETED Phase 2

Mayo Acute Stroke Trial for Enhancing Recovery

NCT00805792

COMPLETED Phase 4

The Use of Dual Chamber ICD With Special Programmed Features to Lower the Risk of Inappropriate Shock

NCT00787800

COMPLETED

Confocal Laser Microscopy in Non Erosive Reflux Disease

NCT00588939

COMPLETED NA

L-arginine for Prevention of Kidney Damage in Liver Transplant Recipients

NCT00587418

COMPLETED

Tongue Pull Versus Jaw Thrust

NCT00833118

COMPLETED Phase 2

Lenalidomide, Rituximab, Cyclophosphamide, and Dexamethasone in Treating Patients With Previously Untreated Low-Grade Non-Hodgkin Lymphoma

NCT00784927

COMPLETED Early Phase 1

Nurse Practitioner Hospice Program for Patients With Terminal Metastatic Cancer and Their Families or Caregivers

NCT00896792

COMPLETED Phase 2

A Placebo-Controlled Study of Clonidine for Fecal Incontinence.

NCT00884832

COMPLETED

Influence of Acid Reflux on Stromal Epithelial Interaction in Barrett's Esophagus

NCT01281618

COMPLETED Phase 4

Intravenous Ketorolac for Postoperative Pain in Percutaneous Nephrolithotomy

NCT00765128

COMPLETED

Use of Molecular Breast Imaging (MBI) to Detect Additional Disease in Women With Breast Cancer Who Are About to go to Surgery

NCT00776308

COMPLETED Phase 4

Intravenous Ketorolac for Postoperative Pain in Laparoscopic Donor Nephrectomy

NCT00765232

COMPLETED NA

Stroke Telemedicine for Arizona Rural Residents Trial

NCT00829361

COMPLETED

Effect of Aromatase Inhibitor Therapy on Blood Vessel Function in Postmenopausal Women With Breast Cancer

NCT00719966

COMPLETED NA

Measuring the Feasibility and the Effects of Chair Massage on Pain and Discomfort in the Cardiac Sonographer

NCT00975026

COMPLETED Phase 2

S-Adenosyl-L-Methionine (SAMe) for Smoking Abstinence

NCT00722124

COMPLETED Early Phase 1

3'-Deoxy-3'-[18F] Fluorothymidine and Fludeoxyglucose F 18 PET Scans in Evaluating Response to Cetuximab, Cisplatin, and Radiation Therapy in Patients With Advanced Cancer of the Oropharynx, Larynx, or Hypopharynx

NCT00757549

COMPLETED NA

Comparison of MRI and Molecular Breast Imaging in Breast Diagnostic Evaluation

NCT00591864

COMPLETED Early Phase 1

Single-Photon Emission Computed Tomography, Computed Tomography Lymphoscintigraphy, and Intensity-Modulated Radiation Therapy in Treating Patients Who Have Undergone Surgery for Stage I or Stage II Breast Cancer

NCT00743314

COMPLETED Early Phase 1

Vaccine Therapy in Treating Patients With Previously Treated Stage II or Stage III Breast Cancer

NCT00640861

COMPLETED Phase 1

Lenalidomide, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Diffuse Large Cell or Follicular B-Cell Lymphoma

NCT00670358

COMPLETED

Studying the Effect of Freeze-Dried Table Grape Powder on Blood Estrogen Levels in Postmenopausal Women

NCT00611104

COMPLETED Phase 2

Rituximab, Cyclophosphamide, Bortezomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Low-Grade Follicular Lymphoma, Waldenstrom Macroglobulinemia, or Mantle Cell Lymphoma

NCT00711828

COMPLETED Phase 2

Internal Radiation Therapy With or Without External-Beam Radiation Therapy in Treating Patients With Localized Prostate Cancer

NCT00714753

COMPLETED NA

Transfusion-Induced Alterations of Pulmonary and Immune Function in Mechanically Ventilated Patients

NCT00751322

COMPLETED Phase 1

Dasatinib and Lapatinib Ditolsylate in Treating Patients With Advanced Solid Tumors That Cannot Be Removed By Surgery

NCT00662636

TERMINATED Phase 1

Sorafenib, Lenalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

NCT00687674

COMPLETED

Screening in Myocardial Perfusion Patients

NCT00943241

COMPLETED Phase 3

Comparison of Intraoperative Warming Devices

NCT00711867

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.