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NCT01489930 · ClinicalTrials.gov registry record · NA

Effects of Resistance and Endurance Training on Synthesis of Individual Muscle Proteins in Young and Older Adults

A NA study, sponsored by Mayo Clinic.

Completed
Registry status
NA
Development phase
67
Enrollment target

NCT01489930: Completed NA study, sponsored by Mayo Clinic.

NCT01489930 is a NA study that has completed, run by Mayo Clinic. The registered enrollment target is 67 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01489930, a NA study, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
NA
Development phase
67 participants
Enrollment target

Study Summary

Loss of skeletal muscle strength and skeletal muscle mass occurs with of aging. This are-related decline in skeletal muscle mass and skeletal muscle strength is a major underlying factor contributing to many of the metabolic disorders and frailty of the investigators rapidly expanding aging population. Endurance (aerobic) and resistance exercise training programs have been shown to effectively reverse the age-related decline in metabolic and contractile muscle functions. The investigators will measure synthesis rates of individual muscle proteins in 36 each of young (18-30 yrs) and 36 older (\> 65 yrs) people to determine their response to 8 weeks each of endurance, resistance, combined endurance and resistance training, or placebo exercise training. Hypotheses. 1. to measure fractional synthesis rates of multiple muscle proteins and identify those that are enhanced by an endurance exercise program 2. to determine whether changes in protein synthesis in response to endurance exercise programs are dependent on age 3. to measure fractional muscle synthesis rates of multiple muscle proteins and to identify those that are enhanced by a resistance exercise program 4. to determine whether changes in protein synthesis in response to resistance exercise programs are dependent on age

Interventions

  • BEHAVIORAL Resistance exercise
  • BEHAVIORAL Endurance exercise
  • BEHAVIORAL Control/Combined training

Trial Details

FieldValue
Enrollment Target 67 participants
Start Date 2008-05
Est. Completion 2011-02
Phase NA

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT01489930

The ClinicalTrials.gov registry entry for NCT01489930 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 67 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Resistance exercise is the first listed.

NCT01489930 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01489930 about?

NCT01489930 is a clinical study titled "Effects of Resistance and Endurance Training on Synthesis of Individual Muscle Proteins in Young and Older Adults". Loss of skeletal muscle strength and skeletal muscle mass occurs with of aging. This are-related decline in skeletal muscle mass and skeletal muscle strength is a major underlying factor contributing to many of the metabolic disorders and frailty of the investigators rapidly expanding aging populati...

What is the current status of trial NCT01489930?

This trial is currently completed. It is a NA study. The enrollment target is 67 participants. The study started on 2008-05. Estimated completion is 2011-02.

What interventions are being tested in trial NCT01489930?

The interventions under investigation include: Resistance exercise (BEHAVIORAL), Endurance exercise (BEHAVIORAL), Control/Combined training (BEHAVIORAL).

Who is sponsoring clinical trial NCT01489930?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.