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NCT00654160 · ClinicalTrials.gov registry record · Phase 1
Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer
A Phase 1 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 7
- Enrollment target
NCT00654160: Completed Phase 1 study, sponsored by Mayo Clinic.
NCT00654160 is a Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 7 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00654160, a Phase 1 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 7 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy, such as irinotecan, fluorouracil, and leucovorin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of irinotecan when given together with fluorouracil and leucovorin in treating patients with advanced gastrointestinal cancer.
Interventions
- DRUG fluorouracil
- OTHER pharmacological study
- DRUG leucovorin calcium
- OTHER pharmacogenomic studies
- DRUG irinotecan hydrochloride
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2008-06 |
| Est. Completion | 2012-12-03 |
| Phase | Phase 1 |
What the finished NCT00654160 record still lists
NCT00654160 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower).
The record links to 0 conditions, and to 5 interventions - of which fluorouracil is the first listed.
NCT00654160 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00654160 about?
NCT00654160 is a clinical study titled "Irinotecan, Fluorouracil, and Leucovorin in Treating Patients With Advanced Gastrointestinal Cancer". RATIONALE: Drugs used in chemotherapy, such as irinotecan, fluorouracil, and leucovorin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: ...
What is the current status of trial NCT00654160?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 7 participants. The study started on 2008-06. Estimated completion is 2012-12-03.
What interventions are being tested in trial NCT00654160?
The interventions under investigation include: fluorouracil (DRUG), pharmacological study (OTHER), leucovorin calcium (DRUG), pharmacogenomic studies (OTHER), irinotecan hydrochloride (DRUG).
Who is sponsoring clinical trial NCT00654160?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00654160's enrollment target sits among peer trials
7 1972nd of 2000 higher than 27 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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