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NCT00751322 · ClinicalTrials.gov registry record · NA
Transfusion-Induced Alterations of Pulmonary and Immune Function in Mechanically Ventilated Patients
A NA study, sponsored by Mayo Clinic.
- Completed
- Registry status
- NA
- Development phase
- 100
- Enrollment target
NCT00751322: Completed NA study, sponsored by Mayo Clinic.
NCT00751322 is a NA study that has completed, run by Mayo Clinic. The registered enrollment target is 100 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00751322, a NA study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
Study Summary
Specific aim: To test whether transfusion of leukoreduced red cells of lesser storage time (versus conventional storage time) reduces mild alterations in pulmonary function and immune activation in critically ill patients with mechanically ventilated lungs. We propose to perform a prospective, randomized, double-blind clinical trial in critically ill patients whose lungs are mechanically ventilated, and who have orders to receive transfusion of at least one unit of packed red cells, comparing pulmonary function between patients randomly allocated to receive a unit of red cells stored for 5 days or less, with similar patients randomly allocated to receive a unit of red cells stored conventionally (median 21 days). We will test the hypothesis that transfusion of red cells of lesser storage age, (5 days or less) will produce the less changes of pulmonary function and immune activation than will transfusion of red cells of conventional storage age (median 21 days).
Interventions
- OTHER RBC transfusion of 5 days or less storage age
- OTHER RBC transfusion of conventional storage age
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2008-08 |
| Est. Completion | 2011-12 |
| Phase | NA |
What the finished NCT00751322 record still lists
NCT00751322 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 2 interventions - of which RBC transfusion of 5 days or less storage age is the first listed.
NCT00751322 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00751322 about?
NCT00751322 is a clinical study titled "Transfusion-Induced Alterations of Pulmonary and Immune Function in Mechanically Ventilated Patients". Specific aim: To test whether transfusion of leukoreduced red cells of lesser storage time (versus conventional storage time) reduces mild alterations in pulmonary function and immune activation in critically ill patients with mechanically ventilated lungs. We propose to perform a prospective, rand...
What is the current status of trial NCT00751322?
This trial is currently completed. It is a NA study. The enrollment target is 100 participants. The study started on 2008-08. Estimated completion is 2011-12.
What interventions are being tested in trial NCT00751322?
The interventions under investigation include: RBC transfusion of 5 days or less storage age (OTHER), RBC transfusion of conventional storage age (OTHER).
Who is sponsoring clinical trial NCT00751322?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00751322's enrollment target sits among peer trials
100 840th of 2000 higher than 1,081 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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