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NCT00814892 · ClinicalTrials.gov registry record · Phase 2

Vaccine Therapy in Treating Patients With Non-Metastatic Prostate Cancer

A Phase 2 study, sponsored by Mayo Clinic.

Terminated
Registry status
Phase 2
Development phase
2
Enrollment target

NCT00814892: Clinical Trial Phase 2 study, sponsored by Mayo Clinic.

NCT00814892 is a Phase 2 study that was terminated before completion, run by Mayo Clinic. The registered enrollment target is 2 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00814892, a Phase 2 study, was terminated before completion, sponsored by Mayo Clinic.

TERMINATED
Registry status
Phase 2
Development phase
2 participants
Enrollment target

Study Summary

RATIONALE: Vaccines made from tumor cells or dendritic cells may help the body build an effective immune response to kill tumor cells. It is not yet known which vaccine is more effective in treating patients with prostate cancer. PURPOSE: This phase II trial is studying how well the combination of a proven effective allogenic whole prostate carcinoma cell (APCC) vaccine co-administered with ex vivo generated dendritic cells (DCs)(DC-APCC) extend the time to prostate cancer progression.

Primary Outcome

Progression free was defined as being free of radiographically detectable disease/metastases at one year after registration and having a prostate-specific antigen (PSA) level \<200.0 ng/mL.

Interventions

  • BIOLOGICAL allogeneic tumor cell vaccine
  • BIOLOGICAL therapeutic autologous dendritic cells

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2009-01
Est. Completion 2010-03
Phase Phase 2
Mayo Clinic

2,844 total trials

Why NCT00814892 stopped before completion

NCT00814892 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 2 interventions - of which allogeneic tumor cell vaccine is the first listed.

NCT00814892 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00814892 about?

NCT00814892 is a clinical study titled "Vaccine Therapy in Treating Patients With Non-Metastatic Prostate Cancer". RATIONALE: Vaccines made from tumor cells or dendritic cells may help the body build an effective immune response to kill tumor cells. It is not yet known which vaccine is more effective in treating patients with prostate cancer. PURPOSE: This phase II trial is studying how well the combination of ...

What is the current status of trial NCT00814892?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 2 participants. The study started on 2009-01. Estimated completion is 2010-03.

What interventions are being tested in trial NCT00814892?

The interventions under investigation include: allogeneic tumor cell vaccine (BIOLOGICAL), therapeutic autologous dendritic cells (BIOLOGICAL).

Who is sponsoring clinical trial NCT00814892?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00814892's enrollment target sits among peer trials

2 2001st of 2000 the lowest of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00814892, the US trial registry maintained by the National Library of Medicine. NCT00814892 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.