Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 48 of 57

COMPLETED NA

A Phase I Study of iPS Cell Generation From Patients With COPD

NCT01860898
COMPLETED Phase 1

Everolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable Solid Tumors Refractory to Standard Therapy

NCT00949949
COMPLETED NA

EUS Guided Celiac Neurolysis

NCT01615653
COMPLETED Phase 2

Effect of Cannabinoid Agonist on Gastrointestinal and Colonic Motor Functions in Patients With Irritable Bowel Syndrome (IBS)

NCT01253408
COMPLETED Phase 2

Varenicline and Bupropion for Smoking Cessation

NCT00935818
COMPLETED

Statin Interchange by Pharmacist Collaborative Practice Agreement (CPA)

NCT01222182
COMPLETED Phase 1

Effects of Gastric Antral Botulinum Toxin Injections in Obese Subjects

NCT00976443
COMPLETED

Biomarkers for Human Heart Failure

NCT03905252
COMPLETED

Identifying Factors Underlying the Discontinuation of Triptans

NCT00890357
COMPLETED

Registry for Study of Coils in Intracranial Aneurysms

NCT01000675
COMPLETED Phase 4

The Effect of Welchol on Glucose Metabolism in Type 2 Diabetics

NCT00951899
COMPLETED Phase 1

Erlotinib for Chemoprevention in Trisomy 7 Positive Primary Sclerosing Cholangitis (PSC)

NCT00955149
COMPLETED

Serum Procalcitonin

NCT00954551
COMPLETED Phase 1

Everolimus and Alemtuzumab in Treating Patients With Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

NCT00935792
COMPLETED Phase 1

The Effects of Decreasing the Lasix Dose on the Cardiorenal System

NCT00982423
TERMINATED Phase 1

Stereotactic Radiation Therapy in Treating Patients With Liver Metastases

NCT00938457
TERMINATED Phase 2

Leuprolide Acetate or Goserelin Acetate Compared With Observation in Treating Patients With High-Risk Prostate Cancer Who Have Undergone Radical Prostatectomy

NCT00937768
TERMINATED Phase 1

Evaluate Use of Mangosteen Juice Added to Usual Care in Reducing Risk of Recurrent Atrial Fibrillation

NCT00951301
COMPLETED Phase 1

Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma

NCT00918333
COMPLETED Phase 4

Greater Occipital Nerve Block for Migraine Prophylaxis

NCT00915473
COMPLETED Phase 1

Modafinil in the Treatment of Fatigue in Patients With Primary Biliary Cirrhosis (PBC)

NCT00943176
COMPLETED Phase 4

Comparison of Burch Urethropexy and Mid-urethral Sling Performed Concomitantly With a Sacral Colpopexy

NCT00934999
COMPLETED Phase 1

Role of Endogenous Estrogen in Growth-Hormone Regulation in Postmenopausal Women

NCT01186796
COMPLETED Phase 1

A Pilot Study of Renal Hypothermia During Partial Nephrectomy

NCT00888641
COMPLETED

Indigo Carmine Staining and Narrow Band Imaging (NBI) of Colonic Mucosa for Detection of Dysplasia in Ulcerative Colitis

NCT00961948
COMPLETED

Effect of Surgery and Radiation Therapy on Tc-99M Sestamibi Uptake Patterns in Molecular Breast Imaging

NCT01027767
COMPLETED NA

Wiser Choices in Osteoporosis Choice II: A Decision Aid for Patients and Clinicians

NCT00949611
TERMINATED

Breath Test for Women Receiving Tamoxifen in the Prevention or Treatment of Breast Cancer

NCT00873366
COMPLETED Early Phase 1

Pentoxifylline Treatment of Acute Pancreatitis

NCT01292005
COMPLETED

Fiber Formula Study Among Radiation Oncology Patients

NCT00888147
COMPLETED Phase 1

An Open Label Study of the Effects of Eculizumab in Neuromyelitis Optica

NCT00904826
COMPLETED Phase 2

Effect of Vitamin D3 Supplementation on Insulin Resistance and Cardiovascular Risk Factors in Obese Adolescents

NCT00858247
COMPLETED Phase 2

Cheno Effect on Transit in Health and IBS-C

NCT00912301
COMPLETED Early Phase 1

Stellate Ganglion Nerve Block in Treating Women With Hot Flashes

NCT00879164
COMPLETED

HISTOACRYL: A Study of Its Efficacy in Final Scar Formation

NCT00890578
COMPLETED NA

Low Dose Molecular Breast Imaging as a Screening Tool for Women With Dense Breasts

NCT01925170
TERMINATED NA

Confocal Endomicroscopy for Biliary Strictures -Phase I

NCT00892632
COMPLETED Phase 1

Adrenal Responsiveness During the Perioperative Period in Children Undergoing Congenital Cardiac Surgery

NCT01839812
COMPLETED

Evaluation of Radiculitis Following Use of Bone Morphogenetic Protein-2 for Interbody Arthrodesis in Spinal Surgery

NCT00984672
COMPLETED NA

Wiser Choices in Acute Myocardial Infarction

NCT00888537
COMPLETED

Lung Injury Prediction Study

NCT00889772
COMPLETED Phase 2

Pentostatin, Cyclophosphamide, and Rituximab With or Without Bevacizumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

NCT00816595
COMPLETED NA

Varenicline for the Treatment of Smokeless Tobacco

NCT00813917
COMPLETED Phase 1

Hemin in Healthy Subjects

NCT00882804
COMPLETED

Intestinal Wall Remodeling (Infliximab Therapy) in Crohn's Disease Patients Undergoing Serial Computed Tomography (CT) Enterography

NCT00819663
COMPLETED

The Use of Molecular Breast Imaging in the Evaluation of Tumor Response to Neoadjuvant Therapy in Women With Breast Cancer

NCT01023802
COMPLETED NA

Lp-PLA2 and Coronary Atherosclerosis in Humans

NCT01557088
COMPLETED Phase 4

Rituximab in Progressive Immunoglobulin A (IgA) Nephropathy

NCT00498368
COMPLETED Phase 1

A Pilot Study to Examine the Role of Nitazoxanide to Prevent Recurrence of Hepatitis C After Transplantation

NCT01074203
TERMINATED Phase 1

B-type Natriuretic Peptide (BNP) in Human Hypertension

NCT00953472
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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

Therapeutic Areas

Healthy 36
Malignant Solid Neoplasm 35
Obesity 31
Breast Cancer 25
Breast Carcinoma 21
Hematopoietic and Lymphatic System Neoplasm 20
Hematopoietic and Lymphoid System Neoplasm 12
Heart Failure 11
Cancer 11
Prostate Carcinoma 9

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Related

Compare saved trials side-by-side

Read our methodology - how this data is sourced, computed, and verified.
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.