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NCT00732680 · ClinicalTrials.gov registry record · Phase 1
Benefits of the Use of Botox in the Treatment of Empty Nose Syndrome Syndrome
A Phase 1 study, sponsored by Mayo Clinic.
- Terminated
- Registry status
- Phase 1
- Development phase
- 9
- Enrollment target
NCT00732680: Clinical Trial Phase 1 study, sponsored by Mayo Clinic.
NCT00732680 is a Phase 1 study that was terminated before completion, run by Mayo Clinic. The registered enrollment target is 9 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00732680, a Phase 1 study, was terminated before completion, sponsored by Mayo Clinic.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 9 participants
- Enrollment target
Study Summary
Empty Nose Syndrome patients suffer from disabling physical symptoms and considerable distress. To date there is no definitive cure for these symptoms. Established treatment modalities include saline irrigation, surgical implantation of materials or simply use of cotton wads/ silicon cones to simulate the resistive action to airflow of the resected turbinates. This study will research the effectiveness of a new treatment modality in the treatment of Empty Nose Syndrome. This novel treatment method involves the use of botulinum toxin type A (Botox).
Primary Outcome
The SNOT 22 is a validated measure of health related quality of life in sinonasal disease. It is a 22 item questionnaire with each item assigned a score ranging from 0-5. The total score may range from 0-110 and lower scores represent better health related quality of life.
Interventions
- DRUG Botulinum Toxin Type A
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2008-12 |
| Est. Completion | 2009-11 |
| Phase | Phase 1 |
Why NCT00732680 stopped before completion
NCT00732680 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 1 intervention - of which Botulinum Toxin Type A is the first listed.
NCT00732680 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00732680 about?
NCT00732680 is a clinical study titled "Benefits of the Use of Botox in the Treatment of Empty Nose Syndrome Syndrome". Empty Nose Syndrome patients suffer from disabling physical symptoms and considerable distress. To date there is no definitive cure for these symptoms. Established treatment modalities include saline irrigation, surgical implantation of materials or simply use of cotton wads/ silicon cones to simula...
What is the current status of trial NCT00732680?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2008-12. Estimated completion is 2009-11.
What interventions are being tested in trial NCT00732680?
The interventions under investigation include: Botulinum Toxin Type A (DRUG).
Who is sponsoring clinical trial NCT00732680?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00732680's enrollment target sits among peer trials
9 1955th of 2000 higher than 42 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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