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NCT03266068 · ClinicalTrials.gov registry record
Epidemiology and Pathophysiology of Post-Infectious Functional GI Disorders
A clinical trial, sponsored by Mayo Clinic.
- Completed
- Registry status
- 120
- Enrollment target
NCT03266068: Completed study, sponsored by Mayo Clinic.
NCT03266068 is a clinical trial that has completed, run by Mayo Clinic. The registered enrollment target is 120 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03266068 has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- 120 participants
- Enrollment target
Study Summary
Some people develop chronic abdominal pain with diarrhea or constipation after an episode of acute bacterial gastroenteritis. These symptoms can be consistent with post-infectious irritable bowel syndrome (IBS) and can last long after the acute infection is over. The exact reason why certain individuals develop these symptoms whereas others don't is not exactly clear. The researchers are studying changes in gastrointestinal permeability (movement of contents across the lining of the intestine) and transit (movement of food through the gastrointestinal tract). The researchers are also studying if there are any genetic risk factors that are associated with development of this disorder.
Primary Outcome
The scintigraphic method is used to measure colonic transit. An isotope is adsorbed on activated charcoal particles and delivered to the colon in a delayed release capsule. Anterior and posterior gamma images are taken hourly. The geometric center (GC) is the weighted average of counts in the different colonic regions. The scale ranges from 1 to 5; a high GC implies faster colonic transit, a GC of 1 implies all isotope is in the ascending colon, and a GC of 5 implies all isotope is in the stool.
Interventions
- GENETIC DNA Analysis of Blood Sample
- PROCEDURE Flexible sigmoidoscopy with colonic biopsies
- PROCEDURE Small bowel and colonic gastrointestinal permeability
- DIAGNOSTIC_TEST Stool sample analysis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2016-09 |
| Est. Completion | 2020-03-11 |
What the finished NCT03266068 record still lists
NCT03266068 is an observational study that tracks outcomes without assigning an intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 4 interventions - of which DNA Analysis of Blood Sample is the first listed.
NCT03266068 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03266068 about?
NCT03266068 is a clinical study titled "Epidemiology and Pathophysiology of Post-Infectious Functional GI Disorders". Some people develop chronic abdominal pain with diarrhea or constipation after an episode of acute bacterial gastroenteritis. These symptoms can be consistent with post-infectious irritable bowel syndrome (IBS) and can last long after the acute infection is over. The exact reason why certain individ...
What is the current status of trial NCT03266068?
This trial is currently completed. The enrollment target is 120 participants. The study started on 2016-09. Estimated completion is 2020-03-11.
What interventions are being tested in trial NCT03266068?
The interventions under investigation include: DNA Analysis of Blood Sample (GENETIC), Flexible sigmoidoscopy with colonic biopsies (PROCEDURE), Small bowel and colonic gastrointestinal permeability (PROCEDURE), Stool sample analysis (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03266068?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
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