Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 32 of 57

COMPLETED

Proton-Based Stereotactic Ablative Body Radiotherapy for Prostate Cancer

NCT03159676

COMPLETED

Genomic Assessment of Patients With Severe Radiation Reactions

NCT03287349

COMPLETED Phase 2

WEE1 Inhibitor AZD1775 With or Without Cytarabine in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

NCT02666950

TERMINATED NA

Staging of Superficial EAC Using VLE

NCT03385343

COMPLETED

Genetic Biomarker Discovery for Metastatic Prostate Cancer

NCT03228810

COMPLETED NA

Support Person Intervention to Promote a Smoking Helpline Among Under Resourced Smokers

NCT03096145

COMPLETED

Pharmacokinetic Profiling of Pembrolizumab and Nivolumab in Patients With Melanoma and/or Non-Small Cell Lung Cancer

NCT05740501

COMPLETED Phase 2

Ixazomib Citrate, Lenalidomide, Dexamethasone, and Daratumumab in Treating Patients With Newly Diagnosed Multiple Myeloma

NCT03012880

COMPLETED NA

Pilates Pelvic Floor Strengthening Program to Improve Urinary Incontinence

NCT03118557

COMPLETED NA

AKI Prevention and Early Intervention in Patients Undergoing VAD Placement

NCT03236831

COMPLETED NA

Understanding the Pathophysiology and Effects of Diaphragmatic Breathing in Upright Gastroesophageal Reflux

NCT02972047

COMPLETED NA

Shared Decision Making in Parents of Children With Acute Otitis Media

NCT02872558

COMPLETED Phase 1

Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery

NCT02700230

TERMINATED NA

Endoscopic Mucosal Resection and Cellular Matrix

NCT03240679

COMPLETED NA

Pericardial Resection to Treat Heart Failure

NCT03073668

COMPLETED Phase 1

The Effect of Ixazomib on the Latent HIV Reservoir

NCT02946047

COMPLETED

The TOGETHER Project - Liver

NCT03874286

COMPLETED Phase 1

Stem Cell Fistula Plug in Post Surgical Leak Fistulas

NCT02807389

COMPLETED NA

Implementing a Paced Deep Breathing Module to Decrease Preoperative Anxiety in Gynecological Surgery Patients

NCT03078790

COMPLETED Phase 1

Diagnostic Utility of F-18 Florbetapir PET/MR in Peripheral Nerve Amyloidosis

NCT03019029

TERMINATED Phase 1

Ibrutinib, Lenalidomide, and Dexamethasone in Treating Patients With Multiple Myeloma Ineligible for Transplant

NCT03015792

COMPLETED NA

Sponge and Eosinophil Peroxidase (EPO) Staining

NCT03078023

COMPLETED NA

Impact of Low-dose Tamoxifen on BPU

NCT02979301

TERMINATED NA

MRI to Assess Fibrosis in Eosinophilic Esophagitis Patients

NCT03446118

TERMINATED NA

Exercise Intervention - and Impact on Hospitalization

NCT03106220

COMPLETED

Evaluation of Cognitive-Communication Deficits Following Treatment of Primary Brain Tumor Patients

NCT03090386

TERMINATED NA

Dermatome Electrical Stimulation on Individuals With Overweight and Class I Obesity

NCT03261531

COMPLETED NA

Feasibility of a Standardized Video for Patient Education and as a Decision Aid on Code Status for Patients in the Emergency Department Pending Admission to the Hospital

NCT03213197

COMPLETED NA

Mobile and Remote Monitoring of Seating Pressure for Wheelchair Users With SCI

NCT03987243

COMPLETED

Intraoperative Non-invasive Eye Movement Monitoring

NCT03046615

COMPLETED NA

Vacuum-Assisted Dressings (V-AD) in the Management of Open Chest Wounds

NCT02803164

COMPLETED NA

Ergonomics in Robotic Surgery

NCT03096769

COMPLETED NA

Addressing Diabetes Together

NCT03046498

COMPLETED Phase 4

Gabapentin for Alcohol Withdrawal Syndrome

NCT03012815

COMPLETED NA

Step Rate in Recreational Runners

NCT03057522

COMPLETED NA

Team-Based Delivery of Care in Outpatient Settings

NCT03062670

COMPLETED Phase 1

Effects of Aprepitant on Satiation, Gastric Volume, Gastric Accommodation and Gastric Emptying

NCT02989467

COMPLETED NA

Liver Fibrosis Evaluation Using Ultrasound Shear Wave Imaging

NCT03637959

COMPLETED Phase 1

Platelet Rich Plasma Versus Minoxidil Foam for Treatment of Androgenic Alopecia in Women

NCT03488108

COMPLETED NA

Determining Lipid Content in Stool After Alpha-cyclodextrin

NCT03002168

TERMINATED NA

Vascular Boot Warming Program After Acute Deep Vein Thrombosis (DVT) ± Pulmonary Embolism (PE)

NCT03465735

COMPLETED NA

Small Bowel Microbiota Characterization in Healthy Individuals Before and After Consumption of a Western Diet

NCT03266536

COMPLETED NA

The MOTS (Medication Overuse Treatment Strategy) Trial

NCT02764320

COMPLETED NA

Integrative Cognitive-Affective Therapy for Adolescent Eating Disorders

NCT03324724

TERMINATED NA

Automatic Periodic Stimulation and Continuous Electromyography (EMG) for Facial Nerve Monitoring During Parotidectomy

NCT03172520

COMPLETED Phase 1

Safety and Efficacy of ANX-042 in Human Cardiorenal Syndrome

NCT03019653

COMPLETED Phase 2

L-carnitine for Fatigue in COPD

NCT03008356

COMPLETED

Cancer-Associated Muscle Atrophy and Weakness: An Investigation of Etiology

NCT03012139

COMPLETED NA

My Life, My Healthcare

NCT03017196

TERMINATED NA

Defining the Role of the Gut Microbiome in Mediating the Effects of Obesity on Intestinal Stem Cells

NCT02863029

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.