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NCT02880137 · ClinicalTrials.gov registry record · Phase 4

Real Time Myocardial Perfusion Echocardiography for Coronary Allograft Vasculopathy

A Phase 4 study of Cardiac Allograft Vasculopathy, sponsored by Mayo Clinic.

Completed
Registry status
Phase 4
Development phase
36
Enrollment target
1
Study location

NCT02880137: Completed Phase 4 study of Cardiac Allograft Vasculopathy, sponsored by Mayo Clinic.

NCT02880137 is a Phase 4 study of Cardiac Allograft Vasculopathy that has completed, run by Mayo Clinic. The registered enrollment target is 36 participants, below the 119-participant average among 3 other Cardiac Allograft Vasculopathy trials with a reported enrollment target (70% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02880137, a Phase 4 study of Cardiac Allograft Vasculopathy, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 4
Development phase
36 participants
Enrollment target
1
Study location

Study Summary

Is real-time myocardial perfusion echocardiography (RTMPE) a feasible and effective non-invasive method to detect significant Coronary Allograft Vasculopathy in pediatric and adult cardiac transplant recipients? Will perfusion deficits correlate with significant coronary artery stenosis identified by standard stress echocardiography and Invasive Coronary Angiography (ICA), and identify diffuse small vessel disease more effectively than current non-invasive techniques?

Primary Outcome

A perfusion defect will first be identified using clinically indicated invasive coronary angiography (ICA). The presence of a perfusion defect will then be identified using non-invasive real time myocardial perfusion echocardiography (RTMPE).

Conditions Studied

Cardiac Allograft Vasculopathy

Interventions

  • DRUG Perflutren Lipid Microsphere
  • PROCEDURE RTMPE

Study Locations (1)

Minnesota

  • Mayo Clinic in Rochester - Rochester

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2016-09
Est. Completion 2018-06-30
Phase Phase 4
Mayo Clinic

2,844 total trials

What the finished NCT02880137 record still lists

NCT02880137 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 119-participant average among 3 other Cardiac Allograft Vasculopathy trials with a reported enrollment target (70% lower).

The record links to 1 condition, with Cardiac Allograft Vasculopathy appearing as the primary indexed condition, and to 2 interventions - of which Perflutren Lipid Microsphere is the first listed.

NCT02880137 reports a single indexed study location in Minnesota.

Frequently Asked Questions

What is clinical trial NCT02880137 about?

NCT02880137 is a clinical study titled "Real Time Myocardial Perfusion Echocardiography for Coronary Allograft Vasculopathy". Is real-time myocardial perfusion echocardiography (RTMPE) a feasible and effective non-invasive method to detect significant Coronary Allograft Vasculopathy in pediatric and adult cardiac transplant recipients? Will perfusion deficits correlate with significant coronary artery stenosis identified b...

What is the current status of trial NCT02880137?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 36 participants. The study started on 2016-09. Estimated completion is 2018-06-30.

What conditions does trial NCT02880137 study?

This clinical trial studies the following conditions: Cardiac Allograft Vasculopathy.

What interventions are being tested in trial NCT02880137?

The interventions under investigation include: Perflutren Lipid Microsphere (DRUG), RTMPE (PROCEDURE).

Who is sponsoring clinical trial NCT02880137?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02880137 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Related registry views

Source: ClinicalTrials.gov NCT02880137, the US trial registry maintained by the National Library of Medicine. NCT02880137 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.