Mayo Clinic

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Mayo Clinic sits in the top decile of US sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count).

2,844 total trials 544 currently recruiting 1816 completed early-phase tilt top decile by trial count

Mayo Clinic: 2,844 sponsored US clinical trials, 544 recruiting.

Mayo Clinic sponsors 2,844 registered US clinical trials on ClinicalTrials.gov, 544 of them currently recruiting, and 1,816 completed. 252 of these trials are in Phase 3-4 (later-stage) and 821 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 36 trials.

Top-decile sponsor footprint

Mayo Clinic ranks in the top decile of sponsors by registered trial count (#2 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,844 total, page 29 of 57

COMPLETED

Cardiac Output Monitoring in Critically Ill Patient Undergoing Intubation

NCT03525743

COMPLETED Phase 4

Circulating NEP and NEP Inhibition Study in Heart Failure With Preserved Ejection Fraction

NCT03506412

COMPLETED

Myocardial Inflammation in Rheumatoid Arthritis: A Descriptive Study

NCT03776682

COMPLETED Phase 2

Pembrolizumab, Ixazomib Citrate, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma

NCT03506360

COMPLETED

Ultrasound Image Quality of the Brachial Plexus at the Interscalene Space Before and After Shoulder Arthroscopy

NCT03657173

COMPLETED

Postoperative Pain Reported to Nurses and Physicians

NCT03840356

COMPLETED Phase 1

Study of Intracoronary CD34+ Cell Administration in Patients With Early Coronary Atherosclerosis

NCT03471611

COMPLETED NA

Early Integration of Palliative Care Using the BEACON PROQOL in Patients With High Grade Glioma and Their Caregivers

NCT04630379

TERMINATED NA

Exercise to Treat Frailty and Decreased Physical Function in Transplant Candidates

NCT03535584

COMPLETED Phase 1

A Pilot Study of Intralesional Injection of Triamcinolone Acetonide for Desmoid Tumors

NCT03627741

COMPLETED Phase 4

Cardiovascular Effects of Adderall in Healthy Adults.

NCT02979327

COMPLETED NA

This Study Assesses the Impact of Different Sheets on Body Temperature and Sleep

NCT03446820

COMPLETED Phase 4

Maintain Respiratory Muscle Function and Reduce Pneumonia Risk in Cancer Patients

NCT03469271

COMPLETED

Eating With Eosinophilic Esophagitis (EoE)

NCT03581838

TERMINATED Phase 2

Effect of Metformin on Frailty in 12 Subjects

NCT03451006

COMPLETED Phase 2

Hypofractionated Radiation Therapy for Treating Prostate Cancer High-Risk Features Following Radical Prostatectomy

NCT03570827

COMPLETED NA

The Utility of Focused Frailty Interventions on Patients With Advanced Heart Failure

NCT03574662

COMPLETED Phase 4

Pharmacogenomics and Post-Operative Nausea and Vomiting

NCT03503292

COMPLETED Phase 1

Venetoclax, Ixazomib Citrate, and Dexamethasone in Treating Patients with Relapsed Multiple Myeloma

NCT03399539

COMPLETED Phase 2

PDD in Type 2 Diabetes w/wo Diastolic Dysfunction

NCT03744975

COMPLETED Phase 2

Perioperative Ketamine for Pain With Gastric Bypass

NCT03448068

COMPLETED

Evaluating Mepitel in Post-mastectomy Patients and the Role of the Skin Microbiome in Radiation Dermatitis

NCT03519438

COMPLETED NA

Decreasing Agitation in Patients With Dementia Through the Use of Weighted Blankets

NCT03643991

TERMINATED NA

Preventing Lymphedema in Axillary Lymph Node Dissection

NCT03428581

COMPLETED Phase 2

Daratumumab in Treating Transplant-Eligible Patients With Multiple Myeloma

NCT03477539

COMPLETED NA

Treating Sleep Apnea Induced Hypoxemia With Oxygen in Acute Stroke Patients

NCT03300063

COMPLETED Phase 2

Does Early Administration of Tranexamic Acid Reduce Blood Loss and Perioperative Transfusion Requirement

NCT03182751

COMPLETED Phase 2

Valchlor in the Treatment of Lichen Planopilaris

NCT03417141

COMPLETED NA

Multilevel Interventions to Enhance Provider Recommendations for HPV Vaccination

NCT03501992

COMPLETED Phase 1

Cosentyx (Secukinumab) for the Treatment of Adult Onset Pityriasis Rubra Pilaris

NCT03342573

TERMINATED Phase 2

Auranofin and Sirolimus in Treating Participants With Ovarian Cancer

NCT03456700

TERMINATED Phase 1

Direct Tumor Microinjection and FDG-PET in Testing Drug Sensitivity in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma, Hodgkin Lymphoma, or Stage IV Breast Cancer

NCT03432741

COMPLETED NA

Penile Length Maintenance Post-Prostatectomy

NCT03500419

TERMINATED NA

Penile Lengthening Pre-Penile Prosthesis Implantation

NCT03500406

COMPLETED NA

Technology-enhanced Transitional Palliative Care for Family Caregivers

NCT03339271

COMPLETED NA

RCT Comparing Robotically-Assisted vs. Manually-Executed Total Knee Arthroplasties

NCT03482349

COMPLETED Phase 1

F-18 TFB-PET Studies in Cancer Patients Undergoing NIS-containing Viral Therapies

NCT03456908

COMPLETED NA

Integrated Treatment for Youth With Mood Disorders

NCT03800303

COMPLETED NA

Esophageal Balloon Measurements to Better Characterize Thoraco-abdominal Interrelationship Mechanics.

NCT03624491

COMPLETED

Improved Training Program for Fall Prevention of War Fighters

NCT03446131

COMPLETED NA

Hydrodissection as a Treatment for Carpal Tunnel Syndrome

NCT03427983

COMPLETED NA

Remote Monitoring to Improve Physician Monitoring, Patient Satisfaction, and Predict Readmissions Following Surgery

NCT03800329

COMPLETED

Autoimmunity in the Pathogenesis of AF

NCT03498729

TERMINATED Phase 1

Hypertrophic Scar Prevention by Novel Topical Gel Application

NCT03403621

COMPLETED

Utility of Real-Time Contrast Enhanced Ultrasound (CEUS) in the Evaluation of Soft Tissue Hematomas

NCT03357081

COMPLETED NA

Cathodal tDCS in MCI: A Randomized, Double-Blind, Sham-Controlled Pilot Study

NCT03521089

COMPLETED

3M Cavilon Advanced Skin Protectant for the Prophylaxis of Radiation Dermatitis

NCT03546803

COMPLETED NA

Utility of Pharmacogenomic Testing in Patients With Gastrointestinal Disorders

NCT05572593

COMPLETED Phase 3

Hypofractionated Radiation Therapy in Preventing Recurrence in Patients With Breast Cancer After Surgery

NCT03324802

COMPLETED NA

Continuous Versus Intermittent Bolus Infusion of Paravertebral Blocks for Thoracic Surgery

NCT03480984

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Phase Distribution

PhaseTrial count
Phase 1 435
Phase 2 386
Phase 3 86
Phase 4 166

What is open in the Mayo Clinic pipeline

544 recruiting of 2,844 indexed (19% open); 1,816 completed (64%).

Phase mix: 252 late (III/IV) vs 821 early (I/II) (early-phase heavy).

Top condition: Healthy (36 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.