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NCT03535584 · ClinicalTrials.gov registry record · NA
Exercise to Treat Frailty and Decreased Physical Function in Transplant Candidates
A NA study, sponsored by Mayo Clinic.
- Terminated
- Registry status
- NA
- Development phase
- 36
- Enrollment target
NCT03535584: Clinical Trial NA study, sponsored by Mayo Clinic.
NCT03535584 is a NA study that was terminated before completion, run by Mayo Clinic. The registered enrollment target is 36 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03535584, a NA study, was terminated before completion, sponsored by Mayo Clinic.
- TERMINATED
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
Study Summary
Frailty is a condition characterized by slowness, weakness, low physical activity, wasting, and exhaustion. Frailty increases the risk for adverse outcomes following transplant such as increased length of stay in the hospital, mortality, or graft function. No interventions for frailty are known for patients with renal disease, but exercise programs like pulmonary rehabilitation have been effective in improving frailty in patients with other diseases, such as lung disease. The goal of this study is to test whether exercise will also improve frailty among patients who are waiting for a kidney transplant and who are considered frail or pre-frail.
Primary Outcome
Frailty will be determined by Frailty Phenotype (FP) or Short Physical Performance Battery (SPPB) scores. FP is determined by the presence of 3 or more of the following: slowness (measured by gait speed), exhaustion (measured with the CES-D), weakness (measured by hand grip strength), low physical activity level (measured with the MLTPAQ and activity monitoring), and wasting (measured through self-report or by tracking changes in weight). The SPPB consists of a gait speed test, balance testing,
Interventions
- BEHAVIORAL Exercise Program
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2018-06-12 |
| Est. Completion | 2025-03-26 |
| Phase | NA |
Why NCT03535584 stopped before completion
NCT03535584 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Exercise Program is the first listed.
NCT03535584 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03535584 about?
NCT03535584 is a clinical study titled "Exercise to Treat Frailty and Decreased Physical Function in Transplant Candidates". Frailty is a condition characterized by slowness, weakness, low physical activity, wasting, and exhaustion. Frailty increases the risk for adverse outcomes following transplant such as increased length of stay in the hospital, mortality, or graft function. No interventions for frailty are known for ...
What is the current status of trial NCT03535584?
This trial is currently terminated. It is a NA study. The enrollment target is 36 participants. The study started on 2018-06-12. Estimated completion is 2025-03-26.
What interventions are being tested in trial NCT03535584?
The interventions under investigation include: Exercise Program (BEHAVIORAL).
Who is sponsoring clinical trial NCT03535584?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03535584's enrollment target sits among peer trials
36 1541st of 2000 higher than 437 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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