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NCT03627741 · ClinicalTrials.gov registry record · Phase 1
A Pilot Study of Intralesional Injection of Triamcinolone Acetonide for Desmoid Tumors
A Phase 1 study, sponsored by Mayo Clinic.
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
NCT03627741: Completed Phase 1 study, sponsored by Mayo Clinic.
NCT03627741 is a Phase 1 study that has completed, run by Mayo Clinic. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03627741, a Phase 1 study, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
There is research supporting treatment of superficial fibromatoses (palmar fibromatosis and keloids) with triamcinolone acetonide injections. These lesions are histologically similar to deep fibromatoses (desmoid tumors). Currently there is little literature evaluating the response of desmoid tumors to injections of triamcinolone acetonide. The investigators aim to perform a pilot study evaluating the response of desmoid tumors to intralesional triamcinolone. If positive results are observed (based on RECIST criteria), then a phase II study will be initiated.
Primary Outcome
Based on MRI imaging
Interventions
- DRUG Triamcinolone Acetonide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2018-06-07 |
| Est. Completion | 2022-07-05 |
| Phase | Phase 1 |
What the finished NCT03627741 record still lists
NCT03627741 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 1 intervention - of which Triamcinolone Acetonide is the first listed.
NCT03627741 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03627741 about?
NCT03627741 is a clinical study titled "A Pilot Study of Intralesional Injection of Triamcinolone Acetonide for Desmoid Tumors". There is research supporting treatment of superficial fibromatoses (palmar fibromatosis and keloids) with triamcinolone acetonide injections. These lesions are histologically similar to deep fibromatoses (desmoid tumors). Currently there is little literature evaluating the response of desmoid tumors...
What is the current status of trial NCT03627741?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2018-06-07. Estimated completion is 2022-07-05.
What interventions are being tested in trial NCT03627741?
The interventions under investigation include: Triamcinolone Acetonide (DRUG).
Who is sponsoring clinical trial NCT03627741?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03627741's enrollment target sits among peer trials
10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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